Clinical trials
Gastrointestinal Cancer clinical trials
Below are recruiting gastrointestinal cancer clinical trials, each written for real people, not researchers. We’re tracking 161 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04838327Recruiting
Study for rare gut cancer types with targeted treatment
This study looks at rare types of gastrointestinal (GI) cancer and may match you to a targeted treatment. It also collects blood and other samples to better understand your cancer and help researchers learn what works.
Aarhus NAges 18 years+ - NCT06375187RecruitingPhase 1
GC203 TIL for advanced solid tumors
This trial tests an experimental TIL therapy (GC203) for people with advanced solid tumors who have no more standard options. Doctors will take a piece of your tumor, make it into a personalized cell treatment, and give it back to try to fight the cancer.
ShanghaiAges 18–75 - NCT07039526RecruitingPhase 2
Cytalux for finding cancer during surgery
This trial tests a dye called Cytalux that helps surgeons see cancer during surgery. You get the dye before surgery, and it makes cancer cells glow under a special light. This could help doctors remove more cancer.
Dallas, TexasAges 18 years+ - NCT07558447Recruiting
Studying Tiny Particles to Predict Chemotherapy Nerve Damage
This study looks at tiny particles in your blood to understand and potentially predict nerve damage caused by certain chemotherapy drugs. Researchers will monitor you before, during, and after your cancer treatment to see if these particles can help warn doctors about this common side effect.
MilanAges 18 years+ - NCT06681233Recruiting
Cone-beam CT for guiding radiation therapy in cancer patients
This study tests whether a special X-ray called cone-beam CT (CBCT) can help guide radiation therapy more precisely for different types of cancer. If you are already scheduled for radiation and use CBCT as part of your care, you may be able to join.
Columbus, OhioAges 18 years+ - NCT07124351RecruitingPhase 4
Using a special dye to see cancer during surgery
This trial tests a drug called pafolacianine (CYTALUX) that makes cancer cells glow during surgery. It may help doctors see and remove more cancer from the stomach, esophagus, or appendix. You take the drug before surgery, and a special camera shows the glowing cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT05323409Recruiting
Better overall care for certain cancer patients
This study looks at how to improve day-to-day support and coordination between cancer doctors and primary care doctors for people with certain early cancers. It may help if you have other ongoing health problems (like diabetes or high blood pressure) or lifestyle factors that need ongoing management during cancer treatment.
Houston, TexasAges 18 years+ - NCT06340620Recruiting
Comparing a new ultrasound tool to the standard scope
This study compares a new, possibly easier-to-use ultrasound tool (EndoSound Vision System) to the standard echoendoscope for looking at organs like the pancreas, bile duct, or lymph nodes. If you are already scheduled for an endoscopic ultrasound, you may be able to join.
Orlando, FloridaAges 18–100 - NCT07383935Recruiting
Stress ball use during chemotherapy for GI cancer patients
This study tests whether using a stress ball during chemotherapy helps patients with gastrointestinal cancer feel better. It may reduce stress or discomfort during treatment.
ArtvinAges 18 years+ - NCT06655246RecruitingPhase 1
Ziftomenib and imatinib for advanced GIST
This trial tests a new drug, ziftomenib, combined with imatinib for people with advanced or spreading gastrointestinal stromal tumors (GIST) that have a KIT mutation. It may help if your GIST has gotten worse while on imatinib.
Birmingham, AlabamaAges 18 years+ - NCT01048281Recruiting
Study of stomach and esophagus cancer samples
This study looks at stomach (gastric) and esophagus cancer, using clinical information and tissue samples. It may help researchers better understand these cancers and improve future care.
Stanford, CaliforniaAges 18 years+ - NCT03740503Recruiting
Study genes in people who respond unusually to treatment
This study looks at stored tumor samples to understand why some people respond much better or much worse than expected. The goal is to learn what the tumor’s genes might be telling doctors about response to treatment.
Toronto, OntarioAges 18 years+ - NCT06008054RecruitingPhase 2
New drug combo for advanced gastrointestinal cancers
This trial tests two new drugs (BL-B01D1 and SI-B003) alone or with a standard immunotherapy for advanced gastrointestinal cancers. The goal is to see if these combinations shrink tumors and are safe.
Beijing, Beijing MunicipalityAges 18–75 - NCT06190730Recruiting
Remote symptom collection for better recovery after surgery
This trial uses a phone or computer app to track your symptoms after gastrointestinal tumor surgery. It aims to improve your recovery by keeping your care team informed remotely.
Baltimore, MarylandAges 18 years+ - NCT06908629Recruiting
Helping Detroit cancer survivors with social needs
This study looks at how social needs (like finding enough food) affect cancer survivors in the Detroit area. If you join, researchers will work to connect you with resources that might help.
Detroit, MichiganAges 18 years+ - NCT00068003Enrolling by invitation
Harvesting Cancer Cells for Experimental Treatment
This trial collects immune cells from cancer patients or healthy volunteers to develop new experimental cancer treatments. Researchers will take a sample of your tumor or blood cells, grow them in the lab, and study how to use them to fight your cancer.
Bethesda, MarylandAges 18 years+ - NCT04899908RecruitingPhase 2
Brain radiation with or without gadolinium nanoparticles for brain metastases
This trial tests whether adding tiny gadolinium-containing nanoparticles to standard brain radiation can better control brain metastases from certain cancers. It is for people with tumors that have grown after immunotherapy, are from certain cancers (like melanoma, GI, or HER2+ breast), are cystic, are large, or have come back after prior radiation.
Boston, MassachusettsAges 18 years+ - NCT05651672RecruitingPhase 2
Pemigatinib for advanced gut cancers with FGFR gene changes
This Phase 2 trial tests pemigatinib, a targeted medicine, for advanced or metastatic gastrointestinal (GI) cancers that have specific FGFR1–3 gene changes. It’s for people whose cancer has grown despite prior standard treatment, and who may benefit if their tumor has the right genetic change.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06621277Recruiting
Improving care for young adults with GI cancer
This study aims to improve care for younger adults (ages 18-50) with gastrointestinal (GI) tumors. Researchers will test ways to better support patients during and after treatment. If you are 18-50 and being treated for a GI tumor at Heidelberg University Hospital, you may be able to join.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06633224Recruiting
Fatigue and biology in cancer patients getting chemoradiation
This study looks at why some people feel very tired during cancer treatment. Researchers will collect blood and stool samples to study how the body responds to chemotherapy and radiation.
San Francisco, CaliforniaAges 18 years+ - NCT04847063RecruitingPhase 1
Test drug heating inside the abdomen for peritoneal cancer
This Phase 1 trial tests a treatment that delivers heated chemotherapy directly into the abdomen (HIPEC) for certain cancers that have spread only within the abdominal lining. It aims to see how safely and effectively this approach works, especially when doctors can remove as much tumor as possible.
Bethesda, MarylandAges 18–120 - NCT05375643Recruiting
Get help enrolling in a genomics-based cancer trial
This study helps support people who are from groups less represented in cancer genetics research to get enrolled in genomics-based cancer trials. If you’re starting a new patient visit for an advanced stomach, blood, or lung cancer, this may guide you through options that use your genetic information.
Boston, MassachusettsAges 18 years+ - NCT05995821Recruiting
Blood and tissue collection for head and neck cancers
This study collects blood and tissue samples from people with cancers of the head, neck, or upper airway to learn how the immune system responds to these cancers. The goal is to find better ways to treat these diseases in the future.
Baltimore, MarylandAges 18 years+ - NCT06582017RecruitingPhase 1
Study of QXL138AM for advanced solid tumors and multiple myeloma
This trial tests an investigational drug called QXL138AM for people with advanced solid tumors or multiple myeloma that has not responded to standard treatments. The goal is to see if the drug is safe and effective.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for gastrointestinal cancer?
- Yes. Clin2 currently lists 161 recruiting gastrointestinal cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Gastrointestinal Cancer Metastatic
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Cancer of Gastrointestinal Tract
- Upper Gastrointestinal Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.