Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 482 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07544589RecruitingPhase 1
Testing DISP-10 for Advanced Gastrointestinal Cancers
This early-stage trial tests a new experimental therapy called DISP-10 in patients with advanced cancers of the stomach, esophagus, or colon that have spread. The goal is to see if this treatment can help shrink tumors and how safe it is.
Duarte, CaliforniaAges 18 years+ - NCT07552467Recruiting
PET Imaging Scan for Detecting Cancer Using New Radioactive Tracer
This study tests a new type of imaging scan (PET/CT or PET/MR) that uses a radioactive tracer to help doctors better detect and diagnose various cancers. The scan targets a specific protein found in tumors, which may help identify cancer more accurately than standard imaging.
Wuhan, HubeiAges 18 years+ - NCT07558447Recruiting
Studying Tiny Particles to Predict Chemotherapy Nerve Damage
This study looks at tiny particles in your blood to understand and potentially predict nerve damage caused by certain chemotherapy drugs. Researchers will monitor you before, during, and after your cancer treatment to see if these particles can help warn doctors about this common side effect.
MilanAges 18 years+ - NCT07581977Recruiting
A Clip Tool for Removing Small Stomach Growths
This trial tests a new two-tooth clip device designed to help doctors safely remove small gastrointestinal tumors (GISTs) from the stomach using endoscopy—a thin camera inserted through the mouth. The clip may make the removal procedure easier and safer.
BeijingAges 18–85 - NCT07590895Recruiting
Low-FODMAP Diet for Endometriosis Pain and Bowel Symptoms
This study tests whether a low-FODMAP diet (a way of eating that limits certain hard-to-digest foods) can reduce pelvic pain, improve quality of life, and help bowel symptoms in women with endometriosis. Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing pain and digestive problems.
MilanAges 18–45 - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Walnut Creek, CaliforniaAges 18 years+ - NCT07618273Recruiting
Smart phone app for tracking stomach and digestive health
This study tests a smartphone app called ALEX that helps you track digestive symptoms like bloating, stomach pain, or changes in bowel habits over four weeks. Researchers want to see if the app makes it easier to notice patterns in your symptoms and understand your gut health better.
Jacksonville, FloridaAges 18–44 - NCT07643558Recruiting
Fish oil and weight training for cancer patients' muscle health
This study tests whether taking fish oil supplements combined with progressive weight training exercises can help preserve or build muscle strength in cancer patients undergoing treatment. The goal is to help you maintain physical function and quality of life during cancer care.
Erlangen, BavariaAges 18 years+ - NCT07651462Recruiting
Fasting Before Hip Surgery and Gut Health
This study tests whether fasting for 20 days before hip replacement surgery changes your gut bacteria in ways that might help your recovery. Researchers want to understand if this dietary approach affects how well you heal after the operation.
Berlin, State of BerlinAges 18–75 - NCT07651722Recruiting
Pain control and gut recovery after abdominal surgery
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07471490Enrolling by invitation
Stool test study for inflammatory bowel disease vs. irritable bowel syndrome
This study collects stool samples and health information to help develop a new test that may tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have not been diagnosed with a chronic gut disorder, you may be able to join.
Minneapolis, MinnesotaAges 2 years+ - NCT07253155Enrolling by invitation
Probiotics for preventing gut symptoms in overweight adults
This study tests whether taking probiotics can help prevent stomach and gut discomfort in people who are overweight or have obesity. You may be eligible if you are at a certain weight and age, eat a balanced diet, and do not have chronic gut issues.
ColeraineAges 18 years+ - NCT06985277Enrolling by invitation
Urgent endoscopy for maroon or bloody stools
This trial tests if a quick endoscopic exam of the upper digestive tract helps people who come to the hospital with maroon-colored or bloody stools. It may find the source of bleeding and guide treatment.
Bangkok, BangkokAges 18 years+ - NCT06810232Enrolling by invitation
Health factors and longer hospital stay after endoscopy
This study looks at how general health factors (like age and other medical conditions) might affect how long you need to stay in the hospital after a routine stomach or bowel exam called an endoscopy. The goal is to understand which patients may need extra care so hospitals can plan better.
IstanbulAges 18 years+ - NCT06699745Enrolling by invitation
Music vs. white noise for kids during endoscopy
This study compares playing music or white noise during a child's first endoscopy to see which helps them feel more comfortable. It might help your child relax during the procedure.
Istanbul, AvcilarAges 6–12 - NCT06698211Enrolling by invitation
Posaconazole to prevent fungal infection in stem cell transplant patients with gut GVHD
This trial tests if giving the antifungal drug posaconazole as a tablet can prevent serious fungal infections in people who have had a stem cell transplant and develop gut graft-versus-host disease (GVHD), which is a complication where donor cells attack the digestive tract. It may help protect patients who need strong immune-suppressing treatment for GVHD.
TianjinAges 18–75 - NCT06509022Enrolling by invitation
Reflux study after esophageal cancer surgery
This study is for people who have had surgery for esophageal cancer. It uses a special test called PEPTEST to track acid reflux after surgery and find out what affects it.
BeijingAges Any age - NCT05812339Enrolling by invitation
Mapping tests for stomach symptoms using body-surface sensors
This study checks whether a noninvasive “mapping” test placed on the belly and chest can help tell apart people with certain upper stomach symptoms from healthy controls. It may help researchers better understand stomach function and symptoms without relying only on invasive tests.
Calgary, AlbertaAges 18 years+ - NCT05600933Enrolling by invitation
Providing tumor samples to find new treatment targets
This study collects tumor tissue and related blood tests from people who already need a biopsy or surgery as part of their usual care. Researchers use the samples to learn what drives the tumor and how the tumor environment may affect treatment, which could help develop future therapies.
Bethesda, MarylandAges 18 years+ - NCT05501028Enrolling by invitation
Audio-recorded gut symptom interview to help diagnose FGIDs
This trial uses natural-language conversations (spoken interactions) to improve how clinicians evaluate and diagnose functional gastrointestinal disorders, a group of conditions that affect the gut. If you are scheduled for a GI clinic visit or a diagnostic endoscopy, your recorded responses may help build better evaluation tools.
Boston, MassachusettsAges 18 years+ - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT05233631Enrolling by invitation
Registry for people who had endoscopic ultrasound
This trial is a registry that collects information from people who undergo a procedure called endoscopic ultrasound (also known as EUS) at the study center. It helps doctors understand what care is used and what outcomes happen over time.
Dallas, TexasAges 18 years+ - NCT04566341Enrolling by invitation
Study gut problems in Parkinson’s and changes in gut nerves
This study looks at how digestive (gut) problems happen in people with Parkinson’s and whether there are related changes in the nerve tissue in the digestive tract. It may help researchers better understand the cause of these symptoms and find new ways to monitor or treat them.
Boston, MassachusettsAges 40–85
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Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 482 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.