Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 482 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00227253Recruiting
Study center for people with Chromosome 18
This trial is for people with Chromosome 18 (or the parent/guardian of a child with it) to take part in medical checkups and study evaluations. It may help researchers learn more about the condition and how to best evaluate patients safely.
San Antonio, TexasAges Any age - NCT01696734RecruitingPhase 3
Domperidone for difficult stomach and reflux problems
This trial studies whether domperidone can help people whose stomach or reflux symptoms did not improve with usual treatments. It focuses on symptoms like slow stomach emptying, hard-to-control acid reflux, or severe indigestion.
Houston, TexasAges 16 years+ - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT02174549RecruitingPhase 1/Phase 2
Testing a drug with liver artery treatment for liver-spread neuroendocrine cancer
This early-stage study tests a cancer drug called tirapazamine, given along with a liver artery procedure (embolization) to treat liver-dominant metastatic neuroendocrine tumors. It aims to find a safe dose and see whether the combination can better control tumor growth in the liver.
Palo Alto, CaliforniaAges 20–99 - NCT02906943Recruiting
Testing cancer tissue to guide targeted treatment choices
This trial studies advanced solid tumors by using stored tumor samples to look for molecular clues. The goal is to help doctors better choose cancer treatments that may work for your specific tumor.
Hamilton, OntarioAges 18 years+ - NCT02185443RecruitingPhase 2
SBRT radiation for liver metastases that can’t be surgically removed
This trial studies stereotactic body radiation therapy (high-precision radiation given in a few sessions) for liver metastases when surgery isn’t possible. It may help shrink or control tumors in the liver and delay progression in people whose cancer has not spread outside the liver (or only to areas treated with a curative plan).
São Paulo, São PauloAges 18 years+ - NCT02584244RecruitingPhase 1/Phase 2
Testing an imaging scan to find gastrointestinal cancer
This study checks how well the LUM Imaging System can detect cancers of the esophagus, colon, or pancreas during the time you are preparing for surgery. It’s mainly meant to see if the scan works safely and clearly for doctors to find cancer areas.
Boston, MassachusettsAges 18 years+ - NCT02863250Recruiting
Blood transfusion registry for people needing frequent transfusions
This registry collects information from adults who receive frequent red blood cell transfusions. It may help clinicians understand transfusion needs and improve future care.
Melbourne, VictoriaAges 18 years+ - NCT03044223Recruiting
Profiles of immune cells in severe Pseudomonas sepsis
This study looks at patterns of immune cells in people who are critically ill with sepsis caused by Pseudomonas aeruginosa bacteria. It may help doctors better understand how the immune system responds and improve care for this serious infection.
UlmAges 18–90 - NCT05323409Recruiting
Better overall care for certain cancer patients
This study looks at how to improve day-to-day support and coordination between cancer doctors and primary care doctors for people with certain early cancers. It may help if you have other ongoing health problems (like diabetes or high blood pressure) or lifestyle factors that need ongoing management during cancer treatment.
Houston, TexasAges 18 years+ - NCT00068003Enrolling by invitation
Harvesting Cancer Cells for Experimental Treatment
This trial collects immune cells from cancer patients or healthy volunteers to develop new experimental cancer treatments. Researchers will take a sample of your tumor or blood cells, grow them in the lab, and study how to use them to fight your cancer.
Bethesda, MarylandAges 18 years+ - NCT01492231Enrolling by invitation
Study outcomes from endoscopy procedures at a digestive center
This trial collects information about how interventional endoscopy procedures affect patients and outcomes after the procedure. You may be able to join if you’re an adult and scheduled for an endoscopy procedure at the specified digestive disease center.
Orange, CaliforniaAges 18 years+ - NCT07400328RecruitingPhase 2
Stem cell injection to prevent severe mouth sores in transplant
This trial is testing a single injection called Amimestrocel to prevent severe mouth sores in people getting a stem cell transplant. The study is for adults who are receiving high-dose conditioning with total body irradiation or melphalan, which often cause painful mouth inflammation.
Suzhu, JiangsuAges 18–65 - NCT07402226Recruiting
Diet study for bloating with scleroderma
This study tests whether a special diet can help reduce bloating and stomach discomfort in people with scleroderma (systemic sclerosis). You'll follow a specific meal plan to see if it improves your digestive symptoms.
Ann Arbor, MichiganAges 18 years+ - NCT07424469Recruiting
Leaks in the esophagus or stomach: microbiome role
This study looks at the role of tiny organisms (the microbiome) in leaks from the esophagus or stomach. Researchers will take small tissue samples to learn more about these leaks and how to treat them better.
Dallas, TexasAges 18 years+ - NCT07434843RecruitingPhase 2
Pemigatinib for a rare type of GIST
This trial tests a drug called pemigatinib for people with a specific type of GIST (SDH-deficient GIST) that has spread or cannot be removed with surgery. The goal is to see if the drug can help stop the cancer from growing.
Boston, MassachusettsAges 18 years+ - NCT07440667Recruiting
Fluid amounts during planned C-section and recovery
This trial compares giving less fluid versus more fluid during planned C-section surgery to see which approach leads to better recovery afterward.
Niğde, MerkezAges 18–45 - NCT07456852RecruitingPhase 1/Phase 2
Can vasodilators help with chemo side effects in GI cancer?
This trial tests two drugs (isosorbide mononitrate and diltiazem) to see if they can prevent blood vessel damage caused by chemotherapy drugs like 5-FU or capecitabine in people with gastrointestinal cancers.
Rochester, MinnesotaAges 18 years+ - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT07673861Recruiting
Using ctDNA to find resistance and guide cancer treatment
This trial uses a simple blood test to look for changes in your cancer's DNA that might show why your current treatment stopped working. The results could help your doctor choose your next treatment more precisely.
LondonAges 18 years+ - NCT07501663Recruiting
Managing nerve damage from chemo in GI cancer survivors
This study tests different integrative approaches (like acupuncture or supplements) to help GI cancer survivors manage nerve damage from chemotherapy. You may be able to join if you have ongoing numbness and tingling from chemo.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07519915Recruiting
Understanding Nerve Stimulation for Bowel Problems in Children
This research study looks at using sacral neuromodulation—a treatment that uses mild electrical stimulation of nerves in the lower spine—to help children with bowel movement problems. Researchers want to understand how well this treatment works and what improvements matter most to patients and families.
ErlangenAges 3–18 - NCT07539532Recruiting
AI model to predict heart problems after stomach surgery
This study compares a new artificial intelligence tool with traditional methods to predict which patients might have heart-related complications after gastrointestinal surgery. The goal is to find better ways to identify high-risk patients and potentially improve their care.
Hà NộiAges 16 years+
Hear when a new Gastrointestinal trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 482 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.