Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 470 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04907643Recruiting
Virtual reality program to reduce stomach-cancer pain
This trial tests whether virtual reality (VR) can improve pain and other day-to-day symptoms in people with certain gastrointestinal cancers. You’d use VR for pain relief while researchers measure how you’re feeling.
Los Angeles, CaliforniaAges 18–99 - NCT06655246RecruitingPhase 1
Ziftomenib and imatinib for advanced GIST
This trial tests a new drug, ziftomenib, combined with imatinib for people with advanced or spreading gastrointestinal stromal tumors (GIST) that have a KIT mutation. It may help if your GIST has gotten worse while on imatinib.
Birmingham, AlabamaAges 18 years+ - NCT07462247Recruiting
Creating an Image Database for Early Upper GI Cancer
This study aims to build a library of images from patients with early cancers or precancerous spots in the upper digestive tract (esophagus and stomach). If you are scheduled for a standard endoscopy procedure (ESD or biopsy), researchers will use the pictures to help improve early detection.
ShanghaiAges 18 years+ - NCT06190730Recruiting
Remote symptom collection for better recovery after surgery
This trial uses a phone or computer app to track your symptoms after gastrointestinal tumor surgery. It aims to improve your recovery by keeping your care team informed remotely.
Baltimore, MarylandAges 18 years+ - NCT06696209Recruiting
Best way to measure time during an upper GI endoscopy
This trial compares two ways of measuring time during an upper GI endoscopy (a camera test that looks at your esophagus, stomach, and the start of your small intestine) to see which one helps doctors find possible cancers better. The goal is to improve how these exams are done for people who need them for diagnosis or monitoring.
CoimbraAges 18 years+ - NCT05152472RecruitingPhase 2
Imatinib plus atezolizumab versus imatinib alone for advanced GIST
This Phase 2 trial tests whether adding atezolizumab (an immune medicine) to imatinib works better than imatinib by itself in people with advanced gastrointestinal stromal tumors (GIST) that can’t be fully removed and have progressed after standard treatments. It may help by improving how well tumors respond and how long disease stays under control.
Lyon, RhôneAges 18 years+ - NCT04557969Recruiting
Surgery and tumor testing in gastrointestinal stromal tumors (GIST)
This study looks at how surgery for gastrointestinal stromal tumors (GIST) works, and collects tumor samples to study them under the microscope and by DNA testing. Your results may help researchers better predict tumor behavior and guide future treatment.
Bethesda, MarylandAges 6 years+ - NCT05009927RecruitingPhase 2
Check whether continuing imatinib works after long GIST control
This trial studies people with advanced or metastatic gastrointestinal stromal tumor (GIST) who have been on the drug imatinib for 10 years with stable, non-growing disease. The goal is to see how effective it is to keep imatinib going after this long period.
BesançonAges 18 years+ - NCT06340620Recruiting
Comparing a new ultrasound tool to the standard scope
This study compares a new, possibly easier-to-use ultrasound tool (EndoSound Vision System) to the standard echoendoscope for looking at organs like the pancreas, bile duct, or lymph nodes. If you are already scheduled for an endoscopic ultrasound, you may be able to join.
Orlando, FloridaAges 18–100 - NCT07687706RecruitingPhase 3
Tegoprazan to prevent stomach problems after stroke
This study tests a stomach-protecting medicine called tegoprazan for people who have had a stroke and are starting antiplatelet therapy. It aims to prevent stomach complications like ulcers or bleeding.
Busan, BusanAges 19 years+ - NCT07529808RecruitingPhase 1/Phase 2
New Drug BHB810 for Advanced Stomach Cancer
This trial tests a new drug called BHB810 for gastric (stomach) and gastroesophageal junction cancer that has stopped responding to standard treatments or has no standard options available. The drug targets a protein called CDH17 found on cancer cells and may help slow or shrink the tumor.
Duarte, CaliforniaAges 18 years+ - NCT06631001Recruiting
Abdominal massage for digestion in ICU patients on tube feeding
This study tests if gentle abdominal massage can improve digestion in intensive care patients who are on a breathing machine and receiving liquid food through a tube. It might help prevent gastrointestinal issues like bloating or slow digestion.
MersinAges 18 years+ - NCT06430372RecruitingPhase 1
Dye-guided endoscopy to see gut blood vessels
This trial tests a new dye that lights up blood vessels in the gut during an endoscopy, using a special camera. It may help doctors see abnormal areas more clearly.
Beijing, Beijing MunicipalityAges 18–75 - NCT05837767Recruiting
Radiation study for tumors that spread to soft tissue areas
This study looks at how a planned form of palliative radiation therapy treats certain solid cancers that have spread outside the brain to larger soft-tissue areas. It may help shrink tumors and relieve symptoms, but it also asks you to meet specific safety and treatment-timing rules.
Basking Ridge, New JerseyAges 18 years+ - NCT04565704Enrolling by invitation
Imaging checks on biopsy samples during routine scopes
This study uses special optical imaging during routine upper or lower endoscopy to look at biopsy tissue and compare what the images show with standard lab microscope results. It may help improve how doctors spot abnormal tissue during procedures.
Boston, MassachusettsAges 18 years+ - NCT01313442Recruiting
Give blood and tumor samples for gastrointestinal cancer research
This trial collects blood and tumor tissue from adults with cancer to help researchers study gastrointestinal cancers. If you’re eligible, your participation mainly involves donating samples for research purposes.
Bethesda, MarylandAges 18 years+ - NCT05002166Recruiting
Study of children with inflammatory bowel disease risks
This study looks at the typical features and risk factors in children diagnosed with inflammatory bowel disease (IBD). It may help families understand what affects IBD in kids, even if it is not testing a new treatment.
AsyutAges Up to 18 years - NCT04933669RecruitingPhase 2
Pre-surgery imatinib for high-risk stomach or gut GIST
This trial studies whether taking imatinib before surgery can shrink or control high-risk gastrointestinal stromal tumors (GIST). If you qualify, you would receive imatinib as “neoadjuvant” (before the operation) and then move on to planned surgery.
Hangzhou, ZhejiangAges 18–80 - NCT04363983Recruiting
Study of immune and tumor interactions in digestive cancers
This study looks at how tumors in the digestive system interact with the body’s immune system and the surrounding environment. Results may help improve understanding of these cancers and guide future treatments.
Boulogne-BillancourtAges 18 years+ - NCT05252078RecruitingPhase 2
Anlotinib plus an injection after esophageal cancer surgery
This Phase 2 study tests whether anlotinib tablets combined with an injection (TQB2450) can lower the risk of esophageal squamous cell cancer coming back after surgery. It may help by targeting cancer growth signals and blood-vessel formation to reduce recurrence.
Nanchang, JiangxiAges 18 years+ - NCT05651672RecruitingPhase 2
Pemigatinib for advanced gut cancers with FGFR gene changes
This Phase 2 trial tests pemigatinib, a targeted medicine, for advanced or metastatic gastrointestinal (GI) cancers that have specific FGFR1–3 gene changes. It’s for people whose cancer has grown despite prior standard treatment, and who may benefit if their tumor has the right genetic change.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT04949282Recruiting
Lutetium-177 treatment for advanced somatostatin-positive tumors
This study looks at outcomes for adults with tumors that are advanced (can’t be fully removed or has spread) and are getting worse, where tests show somatostatin receptors. It aims to understand how treatment with lutetium-177 helps people in this situation.
Santiago de Compostela, A CoruñaAges 18–100 - NCT05938309Recruiting
Safety study of laparoscopic surgery for large stomach GISTs
This study looks at how safe laparoscopic surgery is for stomach GISTs that are 5 cm or larger. If you’re eligible and choose to participate, your team will plan and perform surgery and track safety outcomes.
Fuzhou, FujianAges 18–75 - NCT05951517Recruiting
Mycophenolate for stubborn stomach Purpura (HSP) in children
This trial looks at whether mycophenolate mofetil can help children ages 3–18 who have Henoch-Schönlein purpura affecting the gut that does not improve with steroid treatment. It may help reduce serious stomach symptoms like severe belly pain, bleeding, or bowel problems.
Guangzhou, GuangdongAges 3–18
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Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 470 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.