Clinical trials
Gastrointestinal clinical trials
Below are recruiting gastrointestinal clinical trials, each written for real people, not researchers. We’re tracking 469 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07730229Recruiting
Plant-based drink study for healthy adults
This trial looks at how plant-based drinks affect the bacteria in your gut. You would drink a plant-based beverage daily and provide stool samples to see how your gut microbiome changes.
Lund, Skåne CountyAges 18–65 - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT07714538Recruiting
Breath test for detecting gastrointestinal cancers
This study tests whether a simple breath test can help detect different types of gastrointestinal cancers earlier. If you have been recently diagnosed with one of these cancers or have concerning abdominal symptoms but clear test results, your breath may help teach us how to spot these cancers sooner.
Maidstone, KentAges 18 years+ - NCT07708012Recruiting
Laparoscopic and endoscopic surgery for early stomach cancer
This study tests a less invasive surgery for early stomach cancer that combines a camera in the belly with a scope down the throat. It aims to remove the cancer while saving as much of the stomach as possible, which may mean a quicker recovery and better quality of life.
Qingdao, ShandongAges 18–80 - NCT07714499Recruiting
Energy use in healthy people vs. those with intestinal failure
This study looks at how the body uses energy (calories) in people with intestinal failure compared to healthy controls. The results may help improve nutritional care.
LjubljanaAges 18–65 - NCT05878977Recruiting
Testing biomarkers in immunotherapy for advanced melanoma
This trial looks at tissue and scan-related markers (“biomarkers”) to better understand how immunotherapy works in people with advanced melanoma. You may receive standard first-line immunotherapy, and your recent scans and health details will help researchers study why some people respond better than others.
LjubljanaAges 18 years+ - NCT07689201RecruitingPhase 2
Studying a new targeted drug for advanced GIST after other treatments fail
This study tests a new pill called velzatinib for people with GIST that has spread or can't be removed by surgery, after other treatments have stopped working. It may help shrink the tumor or slow its growth.
FukuokaAges 18 years+ - NCT07673861Recruiting
Using ctDNA to find resistance and guide cancer treatment
This trial uses a simple blood test to look for changes in your cancer's DNA that might show why your current treatment stopped working. The results could help your doctor choose your next treatment more precisely.
LondonAges 18 years+ - NCT07676383Recruiting
Better cancer screening with community precision navigation
This trial tests a program to help people at high risk for certain cancers get the free screening tests they need. It aims to make screening easier by providing personalized guidance in the community.
Huaihua, HunanAges 45–74 - NCT07653776Recruiting
Study of wellness products for gut health
This study tests whether certain daily wellness products can improve gut-related quality of life. If you have room to feel better and are willing to take a product without knowing if it's active or a placebo, you may be able to join.
Del Mar, CaliforniaAges 21–105 - NCT07651462Recruiting
Fasting Before Hip Surgery and Gut Health
This study tests whether fasting for 20 days before hip replacement surgery changes your gut bacteria in ways that might help your recovery. Researchers want to understand if this dietary approach affects how well you heal after the operation.
Berlin, State of BerlinAges 18–75 - NCT07651722Recruiting
Pain control and gut recovery after abdominal surgery
This trial tests a combination of two pain-management approaches—a long-acting numbing medicine injected near nerves and a self-administered opioid—to see if they help your gut function better and control pain after bowel or colon surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT05272579RecruitingEarly Phase 1
Phage treatment to help gut development in very preterm babies
This early-phase trial tests whether giving a specific bacteria-fighting treatment (called bacteriophage) through the gut can help preterm babies’ intestinal development mature faster. It may help reduce early gut-related problems, but the study is mainly to check safety and early effects.
CopenhagenAges Any age - NCT07643558Recruiting
Fish oil and weight training for cancer patients' muscle health
This study tests whether taking fish oil supplements combined with progressive weight training exercises can help preserve or build muscle strength in cancer patients undergoing treatment. The goal is to help you maintain physical function and quality of life during cancer care.
Erlangen, BavariaAges 18 years+ - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Louisville, KentuckyAges birth–60 years - NCT07618273Recruiting
Smart phone app for tracking stomach and digestive health
This study tests a smartphone app called ALEX that helps you track digestive symptoms like bloating, stomach pain, or changes in bowel habits over four weeks. Researchers want to see if the app makes it easier to notice patterns in your symptoms and understand your gut health better.
Jacksonville, FloridaAges 18–44 - NCT07618377RecruitingPhase 1
New Drug for Gastrointestinal Tumors After Multiple Treatments
This study tests a new drug called DCC-2618 for patients with GIST (a rare stomach/intestinal cancer) who have already tried at least three other treatments. The goal is to see if this drug can slow or shrink tumors in patients whose cancer has stopped responding to standard medications.
Kashiwa, ChibaAges 18 years+ - NCT07607587RecruitingPhase 1
Testing a new weight-loss drug for people who couldn't tolerate GLP-1 shots
This study tests a new injectable medication called cagrilintide for people with obesity who had to stop GLP-1 drugs (like Ozempic or Wegovy) because of stomach problems. The goal is to see if cagrilintide causes fewer stomach side effects while still helping with weight.
Walnut Creek, CaliforniaAges 18 years+ - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT07590895Recruiting
Low-FODMAP Diet for Endometriosis Pain and Bowel Symptoms
This study tests whether a low-FODMAP diet (a way of eating that limits certain hard-to-digest foods) can reduce pelvic pain, improve quality of life, and help bowel symptoms in women with endometriosis. Endometriosis is a condition where tissue similar to the uterine lining grows outside the uterus, often causing pain and digestive problems.
MilanAges 18–45 - NCT06720558Recruiting
Placebo probiotic effects on gut health in mild GI symptoms
This study tests whether a placebo probiotic can improve gut health and overall well-being in people with mild digestive issues like gas, bloating, or irregularity. If you have mild symptoms that don't stop your daily activities, this trial may help understand if believing you're taking a probiotic can make you feel better.
MilanAges 20–65 - NCT02185443RecruitingPhase 2
SBRT radiation for liver metastases that can’t be surgically removed
This trial studies stereotactic body radiation therapy (high-precision radiation given in a few sessions) for liver metastases when surgery isn’t possible. It may help shrink or control tumors in the liver and delay progression in people whose cancer has not spread outside the liver (or only to areas treated with a curative plan).
São Paulo, São PauloAges 18 years+ - NCT06538610Recruiting
Portable heart monitor for people on FOLFOX chemo
This study will use a small portable heart monitor (Holter) to track your heart rhythm while you receive FOLFOX chemotherapy. The goal is to learn more about how the chemotherapy drug 5-FU affects the heart.
AucklandAges 18 years+ - NCT07586111Recruiting
Plant Foods for Better Gut and Heart Health
This study tests whether eating more plant-based foods improves your gut bacteria, digestion, and heart health markers. You'll follow a structured diet plan for several weeks while providing blood, stool, and urine samples to measure changes.
LondonAges 30–70
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Common questions
- Are there clinical trials for gastrointestinal?
- Yes. Clin2 currently lists 469 recruiting gastrointestinal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gastrointestinal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gastrointestinal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.