Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02811653Recruiting
Brain movement and memory study in early dementia
This study looks at how “slower movement” and brain changes relate to memory and thinking problems in people with early dementia (and some related conditions). It may help researchers understand what brain differences go with these symptoms, using tests and an MRI scan.
AmiensAges 40–85 - NCT02993796Recruiting
Krabbe disease patient and family registry
This registry collects information from people who have Krabbe disease, people at risk, and close family members. It helps researchers learn more about the disease and support future studies.
Buffalo, New YorkAges Any age - NCT02925819Recruiting
Study for severe mitral valve disease when surgery isn’t an option
This trial focuses on people with severe mitral valve narrowing or leaking who still have symptoms even after the best usual medications. It may help find better care and measure health outcomes when surgery is judged too risky or not suitable.
LyonAges 18 years+ - NCT02751060Enrolling by invitation
Blood test for RNA signals to track coronary heart disease
This study checks whether tiny RNA signals found in a blood sample can help identify or monitor coronary heart disease. It may help doctors learn better ways to recognize the condition and track changes soon after symptoms begin.
Wuhan, HubeiAges 18 years+ - NCT02683512Recruiting
Study of GBE deficiency in GSD IV and APBD
This study follows people with GBE deficiency caused by GSD IV or APBD to better understand how the condition works over time. It may help researchers and clinicians plan future care and treatments.
Durham, North CarolinaAges birth–90 years - NCT02824471Recruiting
Testing a chip technology for sickle cell samples
This trial tests a “biochip” device using samples from people with sickle cell disease. If it works, it may help doctors study sickle cell biology more accurately using patient samples.
Cleveland, OhioAges 12 years+ - NCT03021031Enrolling by invitation
Deep brain stimulation for Parkinson’s patients
This trial studies a type of brain stimulation to help reduce symptoms in people with Parkinson’s disease. You may be able to join if you have Parkinson’s and are being considered for this treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT02725060Enrolling by invitation
Study of autoimmune changes in postural tachycardia syndrome
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
Oklahoma City, OklahomaAges 18–50 - NCT02699736Enrolling by invitation
HIV and hepatitis C study in European adults
This study follows people living with HIV who also have hepatitis C antibodies, to better understand how HIV and hepatitis C affect health over time. You may be able to join if you meet the age and enrollment requirements, even if your hepatitis C virus level is currently undetectable.
Buenos AiresAges 16 years+ - NCT02863757Recruiting
Follow-up study for chronic hepatitis B with fatty liver
This study follows people who have chronic hepatitis B and also have fat buildup in the liver (nonalcoholic fatty liver disease). It’s looking at how these conditions behave over time and what may help, using information collected during follow-up visits.
Hong Kong, Hong KongAges Any age - NCT02897908Recruiting
Noninvasive scan to check liver fat and scarring
This study tests a noninvasive FibroScan machine to help measure liver fat and possible liver scarring using information collected in a database. It may help researchers improve how liver problems like fat buildup and scarring are identified and tracked.
Buffalo, New YorkAges 18 years+ - NCT02435810Recruiting
Study of infections and inflammation affecting the nervous system
This study looks at how infections or inflammation involving the brain and spinal cord work, using patient data and samples. It may help researchers better understand these illnesses and improve future care.
Bethesda, MarylandAges 2–110 - NCT02450851Recruiting
Find answers for undiagnosed medical conditions using genetic testing
This study helps look for causes of health problems when no one has been able to give a diagnosis. It tests and shares medical and genetic information (with privacy protections) so researchers can better match findings to possible causes.
Birmingham, AlabamaAges 1 month–100 years - NCT02471287Recruiting
Genetics study for inherited eye conditions
This study looks at genes in people with inherited eye conditions and in close family members who may or may not have the condition. It helps researchers understand what causes these eye diseases and how they might be better studied in the future.
Bethesda, MarylandAges 1–120 - NCT02617966Recruiting
Test of how rod and cone vision work in eye disease
This study measures how your eyes use two types of light-sensing cells (rods for dim light and cones for clearer detail). It may help researchers better understand retinal (retina) diseases and how well vision is functioning.
Bethesda, MarylandAges 5–100 - NCT02327884Recruiting
Study saliva and related diseases to learn health patterns
This study looks at diseases that involve the salivary (saliva) glands, and may also include people with active hepatitis, oral cancer, or healthy adults. Researchers collect blood, urine, saliva, and sometimes tissue to better understand what’s happening and how these conditions relate to saliva and oral health.
Bethesda, MarylandAges 4–100 - NCT02397824Recruiting
Teeth photo study for people with rare diseases
This study looks at how rare diseases can show up in the mouth and teeth, using pictures of your teeth. It may help doctors recognize dental signs earlier and better describe these rare conditions.
Strasbourg, AlsaceAges Any age - NCT02411773RecruitingPhase 1
Test a nerve-blocking medicine in kidney disease
This Phase 1 study tests whether a medicine that reduces nerve signals (“sympatholysis”) is safe and how it affects people with chronic kidney disease. It may help researchers understand new ways to protect the kidneys, but the main goal here is safety.
Decatur, GeorgiaAges 18–75 - NCT02437396Recruiting
Blood tests in stable adults with Gaucher disease
This study measures inflammation and “oxidative stress” (cell stress caused by imbalance in the body) using blood biomarkers in adults with Gaucher disease. It may help researchers understand what’s happening in the body and how treatment status relates to these blood signals.
Minneapolis, MinnesotaAges 18–75 - NCT02636517Enrolling by invitationPhase 1
Fecal microbiome transplant for repeat C. difficile infection
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Philadelphia, PennsylvaniaAges 3–21 - NCT02414347Recruiting
Tau PET scan study for Alzheimer’s disease
This study uses a PET brain scan with a small injected tracer to look for “tau” protein changes linked to Alzheimer’s disease. It may help researchers better understand how tau appears in people who are cognitively normal or have mild dementia.
St Louis, MissouriAges 18 years+ - NCT02258724Recruiting
Adults with congenital heart disease in Swiss GUCH centers
This study is a national registry that collects health information from adults (age 18+) with congenital heart disease. It may help researchers better understand care and outcomes in people treated at specialized Swiss centers.
BaselAges 18 years+ - NCT02418442Recruiting
Kid rheumatic disease registry study for follow-up care
This is an observational study that follows children and teens with rheumatic (joint/inflammatory) diseases to better understand how they develop and are cared for over time. You may help by letting the study contact your family in the future and by completing study tasks as needed.
Birmingham, AlabamaAges Up to 21 years - NCT02471170Enrolling by invitation
Taking blood samples for pancreatic and related cancer research
This study asks people receiving care at the University of Pennsylvania Hospital to provide samples that can help researchers study tumor material. If you have pancreatic disease—or you’re getting care for something else (like a routine colonoscopy)—your samples may be used to compare findings and improve future research.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.