Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05692024RecruitingPhase 1/Phase 2
Coffee and gut bacteria study after colon or rectal cancer
This early-phase study tests whether a coffee-related approach can change gut bacteria and blood “metabolites” after treatment for stage I–III colon or rectal cancer. The goal is to learn if these changes could help improve health after standard cancer treatment.
Boston, MassachusettsAges 18 years+ - NCT05708885Recruiting
Testing a tool to change esophagus muscle movement
This study looks at how a device affects how the esophagus muscles squeeze and relax. It may help people better understand swallowing problems, even if their usual esophagus test looks normal.
Milwaukee, WisconsinAges 18–90 - NCT05700526Enrolling by invitation
3D-printed customized bone grafts for children’s limb problems
This trial is testing 3D-printed, customized bone grafts made from donor bone to help children and teens stabilize corrective surgery for limb bone alignment. It may help patients who need a planned bone cut (osteotomy) plus a large bone graft to hold the correction in place.
BolognaAges 2–18 - NCT05676450Recruiting
Test blood DNA to find lymphoma changes and leftover disease
This study checks a blood test that looks for small DNA fragments (“cell-free DNA”) to find cancer changes that could guide treatment in diffuse large B-cell lymphoma. It also looks for “minimal residual disease,” meaning tiny amounts of lymphoma that may remain after treatment, and whether this test works across community cancer centers in Texas.
Houston, TexasAges 18 years+ - NCT05697562Recruiting
Embolization treatment for hemorrhoid bleeding
This trial studies a procedure that blocks blood flow to bleeding hemorrhoids (called superior rectal arterial embolization). It may help people with hemorrhoid bleeding who are being considered for treatment, especially when bleeding is significant.
JetteAges 18 years+ - NCT05674539Enrolling by invitationPhase 3
Less intense transplant regimen for AML or MDS patients
This trial tests whether a less intense chemotherapy and transplant plan can work for adults with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who are getting a stem cell transplant. It may help reduce transplant-related harm, especially in people considered higher risk due to age or other health factors.
Wuhan, HubeiAges 18 years+ - NCT05682118Recruiting
Using a new heart scan guide to plan blood-flow procedures
This trial tests whether a computer guidance system can help doctors choose the right pressure/blood-flow measurements during certain heart artery procedures. It may help ensure treatment decisions are based on the clearest information about narrowed arteries.
Yongin, Gyeonggi-doAges 19 years+ - NCT05703919RecruitingPhase 4
Compare standard vs targeted oxygen for COPD flare-ups
This trial tests whether giving oxygen in a standard way or a more targeted way helps people who are having a COPD flare-up before they reach the hospital. It may help reduce oxygen-related harms while still treating low oxygen during emergency care.
Aarhus NAges 40 years+ - NCT05700149Recruiting
Study tests tumor testing to predict nodal marginal zone lymphoma
This study collects and analyzes tumor samples from people with nodal marginal zone lymphoma to better understand the disease and predict outcomes. It may help doctors characterize the lymphoma more accurately using clinical and lab information.
Miami, FloridaAges 18 years+ - NCT05691036Recruiting
Studying bile acid levels and genes in pregnancy itching
This study looks at bile acid levels and possible genetic changes in people with persistent pregnancy itching. The goal is to better understand the cause of intrahepatic cholestasis of pregnancy and related pregnancy outcomes.
Chandigarh, ChandigarhAges 21–45 - NCT05701059Recruiting
Tests different artificial discs for neck nerve and spinal cord problems
This trial compares two types of artificial disc implants used for certain neck problems. It may help people who have tried non-surgical treatments but still have ongoing nerve symptoms or spinal cord issues from a damaged disc in the neck.
Los Angeles, CaliforniaAges 18–60 - NCT05698745Recruiting
Study of the immune features soon after bowel disease starts
This study looks at immune system changes in people around the time inflammatory bowel disease (IBD) is first diagnosed, and compares different groups (new, very recent, or not found on scope). It may help researchers understand what the immune system looks like early in IBD and later in people who don’t show it on colonoscopy.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05703386Recruiting
Study MRI changes in small-vessel stroke disease
This study looks at how “small-vessel” changes in the brain develop after an ischemic stroke, using repeated MRI scans. It may help researchers better understand what causes these changes and how to track them over time.
Baltimore, MarylandAges 18 years+ - NCT05681702RecruitingPhase 4
Personalizing medicines to reduce bleeding after stent procedure
This trial studies ways to reduce bleeding in people after a stent procedure (PCI) who have been taking two anti-platelet medicines (aspirin plus prasugrel or ticagrelor) for a set amount of time. It may help find a safer plan for preventing blood clots while lowering bleeding risk.
Jacksonville, FloridaAges 18 years+ - NCT05704309Enrolling by invitation
Study of diabetes prevention participants using brain scans
This study looks at how people who previously took part in a diabetes prevention program are doing over time, including brain health using MRI scans for some participants. It may help researchers understand who is at higher risk for memory and thinking problems and why.
Phoenix, ArizonaAges Any age - NCT05704881Recruiting
Using breath CO2 levels to judge COPD flare severity in ER
This study measures an easy breathing signal called end-tidal carbon dioxide (a CO2 reading from your exhaled breath) to help judge how severe a COPD flare is. It may help doctors decide how closely you need monitoring and treatment during emergency care.
Grenoble, IsèreAges 18 years+ - NCT05688579Enrolling by invitationPhase 4
Testing an aldosterone-blocking medicine in hard-to-control hypertension
This trial studies whether a medicine that blocks aldosterone (called an MRA) can improve cardiovascular outcomes in people with high aldosterone levels and high blood pressure. You may be asked to take the study medicine and have blood pressure, heart, and lab tests monitored over time.
Ürümqi, XinjiangAges 30–75 - NCT02872532Recruiting
Freezing testicle tissue in children before cancer treatment
This trial studies how doctors collect and freeze a small piece of testicle tissue from boys to protect future fertility before treatments like chemotherapy or radiation. It may help families preserve options for having children later if testicular function is permanently affected.
Rochester, MinnesotaAges birth–17 years - NCT02390973Recruiting
Bariatric-style surgery vs best diabetes care for long remission
This trial compares surgery plus follow-up care versus the best non-surgical (medical) treatment to help people keep type 2 diabetes in remission for a long time. It may be an option if you have higher body weight and diabetes that’s not well controlled, but safety checks are strict.
Québec, QuebecAges 18–60 - NCT03358979Recruiting
3D eye-surface testing for severe dry eye
This study looks at how a specific eye-surface marker (EMMPRIN) changes on the surface cells in people with severe dry eye. It may help researchers understand disease severity and how new treatments could work for severe symptoms.
ParisAges 18 years+ - NCT05652478RecruitingPhase 2
How HIV prevention drugs affect metabolism in healthy people
This study tests how certain HIV prevention drugs affect the body's metabolism (how it uses energy) in healthy people. It aims to understand side effects before these drugs are used more widely, which could help make future treatments safer.
Bethesda, MarylandAges 18–55 - NCT05656365Recruiting
Study of genes and immunity in PFAPA and other tonsil problems
This study looks at genetic markers and immune system patterns in people with PFAPA (periodic fevers with mouth sores and throat/neck gland symptoms) or similar tonsil problems. It may help researchers understand why these conditions happen and how they might be better diagnosed or treated.
Washington D.C., District of ColumbiaAges 1 month–99 years - NCT05660980RecruitingPhase 1/Phase 2
Oral and monthly shots for HIV control in children
This trial studies whether a child can safely move from HIV medicine taken by mouth to long-acting monthly injections. It looks at keeping HIV levels suppressed (very low) and monitoring side effects and safety over time.
Atlanta, GeorgiaAges 2–11
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.