Testing an aldosterone-blocking medicine in hard-to-control hypertension

This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.

This trial looks at whether adding spironolactone to your current blood pressure medicines works better for people with primary aldosteronism (a condition where your adrenal glands make too much aldosterone, raising blood pressure). You may qualify if you have this form of high blood pressure but have declined surgery or don't have an adenoma.

This trial tests whether a simple steroid-based test can help identify a specific type of high blood pressure called primary aldosteronism. If you have high blood pressure that needs medication, this study may help find a treatable cause.

This trial looks at how a natural hormone called aldosterone (which helps control blood pressure) and a treatment that silences it affect people with high blood pressure. It aims to find better ways to manage high blood pressure by studying real patient data.

This study tests a procedure that blocks tiny arteries in the adrenal gland to treat high blood pressure and low potassium caused by aldosteronism. It may be an option if you cannot take medications or cannot have surgery.

This study tests whether adjusting a type of blood pressure medication (called a mineralocorticoid receptor antagonist) based on renin levels is safe and helpful for people with primary aldosteronism. It aims to find a better way to manage the condition.