Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05671757RecruitingPhase 1/Phase 2
Daratumumab for primary antiphospholipid syndrome
This early-phase study tests daratumumab, an immune-targeting drug, for people with primary antiphospholipid syndrome (APS). It aims to see whether it can reduce APS activity and improve outcomes while you continue your usual blood-thinning treatment.
Baltimore, MarylandAges 18–65 - NCT05663502Recruiting
Donate blood and tissue samples for HIV-related cancer research
This study collects blood and tissue samples to help researchers learn more about cancers related to HIV/AIDS. You may be able to join if you’re 18+ and have HIV and a cancer diagnosis, or (if HIV-negative) a certain cancer that is closely linked to AIDS-related cancers.
La Jolla, CaliforniaAges 18 years+ - NCT05641688RecruitingPhase 3
PET brain scan study for people with terminal illness
This Phase 3 study tests an amyloid/tau PET brain imaging agent (called [18F]PI-2620). It aims to see how well the scan helps with brain pathology findings in people who are expected to have a life expectancy of 1 year or less.
Phoenix, ArizonaAges 50 years+ - NCT05641662Recruiting
Video games that get you moving for heart failure inactivity
This study tests whether playing “exergames” (motion-based video games) can help people with heart failure who are mostly inactive spend less time sitting. It checks whether the games are safe and practical and whether they can improve activity over time.
PortoAges 18 years+ - NCT05664035Recruiting
Measuring infection patterns in adults with frequent respiratory infections
This study looks at how often “SPAD” happens in adults who get repeated bacterial infections in the chest or sinuses. It aims to better understand your infection frequency and related immune test results, which may help guide future care.
LilleAges 18–65 - NCT05658913Recruiting
Tau PET/CT scan study for people in an ongoing cohort
This study uses a special brain scan (tau PET/CT) to look for a protein called tau, and it ties the scan results to information collected in an existing research program. It may help researchers better understand brain changes over time.
Boston, MassachusettsAges 18–120 - NCT05658965Recruiting
EEG monitoring after early heart surgery in infants
This study looks at whether early brain-wave testing (EEG) around the time of heart surgery in very young babies can predict later learning and development issues. It may help doctors identify children who need extra support sooner.
Lille, Hauts-de-FranceAges 1 day–1 year - NCT05664854Recruiting
Vagus nerve stimulation guided by body imaging
This study uses a painless body scan method (electrical impedance imaging) and a targeted vagus nerve stimulation to see if it helps people with conditions that might respond to this kind of nerve treatment. If you may benefit from vagus nerve stimulation, this trial may help doctors learn whether the approach is effective and safe for you.
London, Greater LondonAges 18 years+ - NCT05653258RecruitingPhase 2/Phase 3
Study cells in fat tissue and aging cells in older adults
This study uses a special lab test on tiny samples from body fat to map different cell types and “senescent” (aging) cells. It may help researchers understand how aging and obesity are linked, which could guide future treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT05640271RecruitingPhase 2
Tocilizumab for acute chest syndrome in sickle cell
This trial studies tocilizumab (a medicine that calms inflammation) to treat acute chest syndrome in people with sickle cell disease. It may help improve symptoms and recovery by targeting key immune signals involved in this complication.
Chicago, IllinoisAges 12 years+ - NCT05642156Recruiting
Ultrafiltration versus usual dialysis in people on hemodialysis
This study compares a specific way of removing fluid during dialysis (isolated ultrafiltration) with conventional hemodialysis. It aims to see how each approach affects blood flow and fluid shifts in people with end-stage kidney disease.
GrazAges 18 years+ - NCT05660746RecruitingPhase 2/Phase 3
Infliximab dose tailored to control Crohn’s inflammation
This trial tests a more precise way to start infliximab (a Crohn’s medicine) and adjust dosing based on how your body responds. It aims to better control Crohn’s inflammation early and keep it under control.
Los Angeles, CaliforniaAges 6–22 - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT05650307Recruiting
Heart and metabolic scan study of weight and rehabilitation
This study uses detailed heart scans and information about metabolism (how your body uses energy) to understand how metabolic treatments and heart rehabilitation may affect your health. You may qualify either as someone undergoing bariatric (weight-loss) care or as part of a heart rehabilitation group—or as a healthy comparison group.
Cleveland, OhioAges 18 years+ - NCT05659147Enrolling by invitationPhase 4
MRI study of pancreas function in children with pancreatic issues
This study uses a special pancreas MRI to see how well the pancreas works and how pancreas disease changes over time. It also compares MRI findings in children with different pancreas conditions, including suspected pancreatic insufficiency and episodes of pancreatitis.
Cincinnati, OhioAges 5–21 - NCT05637814Recruiting
Screening for critical heart defects with extra blood flow checks
This trial tests if adding blood flow measurements to standard pulse oximeter screening better detects critical congenital heart disease in fetuses and newborns. It may help identify babies who need early heart care.
Davis, CaliforniaAges birth–3 weeks - NCT05672368RecruitingPhase 2
Robotic surgery tool for abdominal and pelvic operations
This trial studies a specific robotic surgical system during abdominal and pelvic surgeries. It may help doctors improve how these operations are done using minimally invasive techniques (smaller cuts).
Duarte, CaliforniaAges 18 years+ - NCT05649098RecruitingEarly Phase 1
Testing dupilumab for itchy inherited genetic skin disorders
This early trial tests whether dupilumab can reduce itching in people with certain inherited (genetic) inflammatory skin conditions. It may help by calming skin inflammation that causes ongoing itch and sleep problems.
Chicago, IllinoisAges 6 months+ - NCT05664516RecruitingPhase 2
Oxytocin treatment study for binge eating disorder adults
This Phase 2 trial tests whether oxytocin (a hormone-like medication) can reduce binge-eating symptoms in adults with binge-eating disorder (including related conditions like bulimia or certain feeding/eating disorders). You may be eligible if your symptoms match the trial’s specific diagnosis rules and you can safely take the study medication.
Boston, MassachusettsAges 18–70 - NCT05650411Recruiting
Test new drug-eluting stent with less blood thinner
This study compares a new type of “drug-eluting” stent (a tiny scaffold that slowly releases medicine) and a single blood-thinner plan versus the usual two-drug blood thinner plan after stent placement in the left main coronary artery. It aims to see if the simpler plan can work while keeping the stent safe.
Zurich, Canton of ZurichAges 18 years+ - NCT05656586Recruiting
At-home testing for Parkinson’s patients with a DBS device
This study checks how well people can do specific at-home movement tasks using their Medtronic Percept deep brain stimulation (DBS) system. It may help improve how DBS settings are tested and monitored outside the clinic, which could make care safer and more personalized.
Minneapolis, MinnesotaAges Any age - NCT05647564Recruiting
PET/CT scan to study why prostate cancer resists treatment
This study uses a PET/CT scan to learn how and why prostate cancer becomes resistant to treatment. It may help researchers better match future therapy choices for people whose prostate cancer is progressing.
Madison, WisconsinAges 18 years+ - NCT05673915Recruiting
Brain stimulation study for hard-to-control epilepsy
This trial tests whether noninvasive brain stimulation (using gentle electrical current through the scalp) can reduce seizures in people with epilepsy that has not responded to at least two anti-seizure medicines. If you qualify, you’d also be asked to keep track of seizures in a diary during the study.
Rochester, MinnesotaAges 6 years+ - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
Washington D.C., District of ColumbiaAges 55 years+
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.