Clinical trials
General Population (no Specific Condition or Disease) clinical trials
Below are recruiting general population (no specific condition or disease) clinical trials, each written for real people, not researchers. We’re tracking 10,548 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04824066Recruiting
Using wearables to spot complications early
This study checks whether common wearable devices can predict or detect problems after treatment or surgery. If you join, the researchers will compare what the wearable shows with what happens to you medically, to see if earlier warnings are possible.
Boston, MassachusettsAges 18 years+ - NCT04809506Recruiting
Blood and genetic tests to predict future heart problems
This study looks for new body markers (including possible genetic traits) to better predict who is likely to have future cardiovascular events. Your results could help doctors estimate risk and choose prevention strategies more accurately.
ToulouseAges 18–99 - NCT04848025Recruiting
Custom 3D stents made for blocked airways
This trial studies a computer-planned, custom-made 3D stent to open up narrow, blocked areas of the main airway near the chest. It may help reduce breathing trouble and cough, and prevent complications from the blockage.
Toulouse, ToulouseAges 18 years+ - NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40 - NCT04791748Recruiting
Virtual reality balance training for kids with inner-ear problems
This study uses virtual reality tasks to understand and compare balance and movement in children with long-term inner-ear (vestibular) problems versus those without. It may help doctors learn what supports best balance and safety during daily activities.
ParisAges 7 years+ - NCT04794972RecruitingPhase 1
Testing a targeted antibody for advanced solid tumors
This Phase 1 trial tests a new antibody drug (GNC-039) that targets a specific feature found on some cancer cells. It is for adults with solid tumors that have come back or stopped responding to standard treatment, aiming to see safety and early signs of effectiveness.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04782258RecruitingPhase 3
Testing the safety of tolvaptan in children with ARPKD
This trial is for children from 28 days old up to 18 years who have a rare kidney disease called ARPKD. It will test if the drug tolvaptan is safe for them. The study helps find new treatment options for kids with this condition.
Washington D.C., District of ColumbiaAges 4 weeks–18 years - NCT04821154Recruiting
Testing outcomes after revision knee replacement with a Persona system
This study looks at how well a specific revision knee replacement system (the Persona system) works after earlier knee problems or surgeries. You may be eligible if you need a revision knee and can follow follow-up care instructions; the trial also checks for certain infection, bone, and health-safety factors.
Fayetteville, ArkansasAges 18 years+ - NCT04823663Recruiting
SOCRATES heart rhythm device study registry
This study keeps a registry (a structured record) of people who get certain heart rhythm or heart device procedures using specific Boston Scientific products. The goal is to track outcomes and help improve how these devices are used in real-world care.
JetteAges Any age - NCT04838171Recruiting
Study of White Blood Cells in Donors and Patients
This study looks at white blood cells (the body’s immune cells) to learn more about how they behave in health and/or illness. Participation may help researchers understand immune-related changes and support future treatments.
LondonAges Any age - NCT04816773Enrolling by invitation
Long-term follow-up for specific knee replacement parts
This study follows people for up to 10 years after a knee replacement done with specific manufacturer parts. It helps the company and doctors understand how well these knee implants work and whether they cause any long-term problems.
Fremont, CaliforniaAges 21 years+ - NCT04777357RecruitingPhase 3
Cariprazine for bipolar depression in ages 10 to 17
This Phase 3 study tests whether cariprazine can improve depression symptoms in children and teens with bipolar I disorder, and also tracks side effects. It may help if your depressive episode is ongoing and you meet specific mood and screening score requirements.
Bentonville, ArkansasAges 10–17 - NCT04798430Enrolling by invitationPhase 3
Study drug follow-up for LDL reduction in high-risk cholesterol patients
This Phase 3 study looks at the long-term safety and benefit of OLE LIB003 for people with very high cholesterol or heart disease risk who still need lower LDL (“bad cholesterol”). It’s likely a continuation study for participants who already did earlier LIB003 Phase 3 trials.
Evanston, IllinoisAges 10 years+ - NCT04808505RecruitingPhase 3
Study of enzyme therapy for children with infant-onset Pompe disease
This trial tests how well a new enzyme treatment (cipaglucosidase alfa with miglustat) works and how safe it is in children and babies with infant-onset Pompe disease. It may help by improving muscle function after earlier treatment or, for some babies, starting treatment when no prior enzyme therapy has been given.
Gainesville, FloridaAges Up to 17 years - NCT03209791Recruiting
Study alcohol-related effects on muscle recycling in the liver
This study looks at how alcoholic liver disease may change a natural body clean-up process in muscle. It compares people with alcoholic liver disease to people without it to better understand the biology and identify possible targets for treatment.
Cleveland, OhioAges 18–65 - NCT04630613Recruiting
Studying NOX4 markers in young adults with ADPKD
This study measures a kidney-related marker (NOX4) and other blood/urine signals in people with early-stage ADPKD to better understand disease activity. It may help researchers identify who is likely to progress and why, though it may not be a treatment study.
Rochester, MinnesotaAges 15–40 - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT04741230Recruiting
Test implant for severe corneal thinning to avoid transplant
This study tests a procedure called Xenia corneal lenticule in people with severe keratoconus or severe post-LASIK corneal thinning who want to avoid a corneal transplant. It aims to improve vision while checking safety and how well the new procedure works over time.
Wolverhampton, West MidlandsAges 18–79 - NCT04685200Recruiting
Study causes of primary sclerosing cholangitis using body scans
This study looks at what drives primary sclerosing cholangitis (PSC) and how it affects the body, using a team approach and medical tests like scans and blood work. It may help researchers understand PSC better and could improve future treatment decisions.
Bethesda, MarylandAges 18–90 - NCT04692675Recruiting
MRI study to track prostate cancer in active surveillance patients
This study uses special prostate MRI scans to see how prostate cancer changes over time while you stay on active surveillance. It also looks at prostate tissue to understand your cancer’s genetics, which may help guide future decisions.
Bethesda, MarylandAges 18 years+ - NCT04700657Recruiting
Study dryness patterns in eye graft-vs-host disease
This study looks at how common and how severe corneal nerve-related dryness is in people with chronic graft-vs-host disease (GVHD) after a stem cell transplant. It may help doctors understand which eye problems are most typical and how best to recognize them early.
Indianapolis, IndianaAges 18 years+ - NCT04715191RecruitingPhase 1
CAR T therapy for GPC3-positive pediatric solid tumors
This Phase 1 study tests a customized immune-cell treatment (CAR T cells) made to recognize GPC3, a marker found on some tumors. It’s designed for children and young people whose solid tumors have not been cured by standard treatment and who can safely receive this therapy.
Houston, TexasAges 1–21 - NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT04700579Recruiting
Study lung changes before and after treatment for active TB
This study looks at changes in the lungs and immune system before TB treatment and again after treatment. By sampling lung fluid and comparing it over time, researchers hope to learn signatures that reflect how TB responds to care.
Cape Town, Western CapeAges 18–60
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Common questions
- Are there clinical trials for general population (no specific condition or disease)?
- Yes. Clin2 currently lists 10,548 recruiting general population (no specific condition or disease) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a general population (no specific condition or disease) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a general population (no specific condition or disease) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.