Clinical trials
Genomics clinical trials
Below are recruiting genomics clinical trials, each written for real people, not researchers. We’re tracking 277 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05657405Recruiting
Study of data analytics for people with genetic conditions
This is an observational study that collects health and family history information to see how advanced data analysis can help people with genetic conditions. It may involve website forms, optional conversations, and sometimes an NIH visit, depending on your situation.
Bethesda, MarylandAges 1 day–120 years - NCT06664814RecruitingPhase 2
Study of ManNAc for primary FSGS
This trial tests an investigational drug called ManNAc for people with a specific kidney disease called FSGS that causes protein in the urine. The goal is to see if ManNAc can help reduce protein loss and slow kidney decline.
Bethesda, MarylandAges 18–115 - NCT06595940Recruiting
Genetic study of unusual disease in non-US populations
This study looks for genetic causes of rare or unusual disease patterns in people living outside the United States. If you or a family member has a condition that seems to run in the family, started very early, or has an unusual form, you may be asked to provide a DNA sample and medical history.
MokaAges 2–100 - NCT06357533RecruitingPhase 3
New drug combo for advanced lung cancer with high PD-L1
This trial tests a new two-drug combination (Dato-DXd and an immunotherapy called rilvegostomig) as the first treatment for people with advanced non-squamous lung cancer who have high PD-L1 levels. The goal is to see if this combination works better than current standard options.
Anchorage, AlaskaAges 18 years+ - NCT03854318Recruiting
Study of families with suspected RUNX1 gene changes
This study follows people who have a known or suspected RUNX1 gene variant linked to FPDMM-like features. It may help improve understanding of the gene, and participants may contribute samples that researchers use for genetic testing and research.
Bethesda, MarylandAges 1 day–100 years - NCT00029965Recruiting
Understanding rare storage diseases over time
This study follows people with rare genetic conditions (GM1, GM2, sialidosis, or galactosialidosis) that affect how the body breaks down certain substances in cells. Researchers track how these diseases progress to better understand them and potentially help future patients.
Bethesda, MarylandAges 1 day–100 years - NCT01780168Recruiting
Study of metabolism, infection, and immunity in mitochondrial disease
This study looks at how metabolism, infections, and the immune system work together in people with mitochondrial disease. It aims to learn more about the condition and may help guide future treatments.
Bethesda, MarylandAges 4 weeks–115 years - NCT07242352RecruitingPhase 3
Comparing elacestrant to standard hormone therapy for high-risk early breast cancer
This trial tests a new hormone therapy drug called elacestrant against standard hormone treatments for people with a specific type of early breast cancer (ER+/HER2-) that has a high chance of coming back. The goal is to see if elacestrant works better at keeping the cancer from returning.
Mannheim, Baden-WurttembergAges 18 years+ - NCT00001373Recruiting
Understanding the genetics of autoinflammatory diseases
This study collects genetic samples and medical histories from people with autoinflammatory diseases (like Familial Mediterranean Fever), their relatives, and healthy volunteers to understand how these conditions run in families and what causes them. Participation mainly involves providing a mail-in DNA sample.
Washington D.C., District of ColumbiaAges 2 months–115 years - NCT06851052Enrolling by invitation
How do DNA changes happen in health and disease?
This study is looking at DNA changes (mutations) in healthy people and in people who may have DNA damage from things like the sun, smoking, past diseases, or treatments like radiation. The goal is to better understand how these changes happen and what they mean.
CambridgeAges 18 years+ - NCT06801977Recruiting
Chinese lung cancer study for a rare type
This study is collecting information from people with a rare lung cancer called pulmonary lymphoepithelioma-like carcinoma (a type of lung tumor that looks like certain head and neck cancers). It aims to learn more about the disease and how to better treat it.
Foshan, GuangdongAges 18 years+ - NCT06541080Recruiting
CollectNET 2.0: Blood Sample Collection for Neuroendocrine Tumors
This study collects blood samples from people with neuroendocrine tumors (NENs) to build a sample bank for future research. It looks at how tumors change over time and how they respond to treatment.
Rumst, AntwerpAges 18 years+ - NCT06289270Recruiting
Bladder cancer and urine bacteria study
This study looks at bacteria in urine and the bladder to understand if they play a role in causing bladder cancer. Researchers will compare samples from men with bladder cancer and healthy controls.
Cairo, Giza GovernorateAges 18 years+ - NCT06244433Recruiting
Genetic testing for sudden infant death
This study looks for gene changes that might be linked to sudden unexpected infant death. It compares the DNA of babies who died suddenly with DNA from their parents, to find possible inherited causes.
Nantes, Loire-AtlantiqueAges Any age - NCT06020625Recruiting
Genetic testing for advanced cancers
This trial investigates genetic testing (mutational profiling) in people with various advanced cancers. It aims to understand how these tests can guide more personalized treatment decisions.
RomeAges 18 years+ - NCT06073626Recruiting
Genetic testing study for Black cancer survivors
This study offers free genetic testing to Black or African American people who have had certain cancers. It aims to find inherited gene changes that increase cancer risk and improve health equity.
Washington D.C., District of ColumbiaAges 18–80 - NCT04860453Recruiting
Family genetic testing study for patterns of different cancers
This study checks whether gene tests can help understand cancer risk in families where different relatives had different (discordant) cancers. It may help families and doctors better understand whether hereditary cancer risk is possible, even though some parts use routine standard care as a comparison group.
Cleveland, OhioAges 18–100 - NCT03791086Recruiting
BRIDGE study using health records and genetics for bronchiectasis
This study looks at how bronchiectasis (ongoing lung damage with mucus and infections) may happen by using your medical records and genetic information. It may help researchers find better ways to understand different bronchiectasis types and guide future treatments.
DundeeAges 18 years+ - NCT04731857Recruiting
Genetic testing results study for rare diseases
This study looks at how well different genetic tests (whole exome/genome sequencing and standard genetic tests) work for diagnosing rare genetic diseases and inherited cancer conditions. It may help confirm which testing approach provides the clearest results for families.
TübingenAges Any age - NCT04049604Recruiting
Study of pregnancy cancer risk after unusual DNA screening
This study follows pregnant people who had unusual noninvasive prenatal blood test results, to better understand the natural course and possible causes, including concerns about maternal cancer. You may join during pregnancy or up to 2 years after delivery, and you would share medical information and undergo follow-up visits.
Bethesda, MarylandAges 18–100 - NCT04172025Recruiting
Swiss database for tracking hard-to-treat infections
This study builds a Swiss database using lab genetic testing (whole genome sequencing) plus basic patient information to track outbreaks of serious, drug-resistant, and sometimes high-infectious pathogens. Your data could help researchers understand how these germs spread and how to better prevent them.
BaselAges Any age - NCT05444283Recruiting
Genetic testing to understand repeat pregnancy loss causes
This study looks for genetic clues in ongoing and past pregnancies to help explain why some people miscarry repeatedly. The results may help doctors better predict and prevent future pregnancy loss.
Aurora, ColoradoAges 18–50 - NCT02363595Recruiting
Genetic clues for how small thyroid cancers may grow
This study looks at gene changes to predict whether a small papillary thyroid cancer found on biopsy is likely to stay stable or grow over time. It may help doctors choose who can safely stay on watchful waiting.
New York, New YorkAges 18 years+ - NCT03632239Enrolling by invitation
Share whole-genome or exome data for research
This trial is about building a large library of genetic test results (whole exome or whole genome sequencing) that researchers can use. You may be eligible if your sequencing data is available and you (or your study contact) can be reached again so researchers can include your information responsibly.
Bethesda, MarylandAges 4–120
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Common questions
- Are there clinical trials for genomics?
- Yes. Clin2 currently lists 277 recruiting genomics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genomics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genomics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.