Clinical trials
Genomics clinical trials
Below are recruiting genomics clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06935019Enrolling by invitation
Genome sequencing for kids with undiagnosed rare diseases
This study offers genome sequencing (a complete look at your child's DNA) to help diagnose a suspected rare disease faster. It's for children who are newly referred to the genetics clinic at SickKids or CHEO and haven't had this type of testing before.
Ottawa, OntarioAges Up to 18 years - NCT02288676Recruiting
Genetic testing to help diagnose ovarian or uterine cancer earlier
This study tests genetic (DNA) information to help doctors identify ovarian or uterine (endometrial) cancer sooner. You may be asked to do this around the time of planned surgery, when tissue is removed and can be checked for genetic clues.
Montreal, QuebecAges 18 years+ - NCT06880094Recruiting
Genetic study of complex or inherited cleft lip and palate
This study uses a new genetic test called Optical Genome Mapping to look for hidden genetic causes of cleft lip or palate that are syndromic, complex, or run in families. It may help find answers for people who haven't gotten a genetic diagnosis yet.
AmiensAges Any age - NCT06762678Recruiting
Studying genes in neurodevelopmental disorders with birth defects
This study is for children or adults with neurodevelopmental conditions and unusual physical features, where standard genetic tests haven't found a cause. Researchers will use RNA and DNA sequencing to look for hidden genetic explanations, which could guide better care.
AngersAges Any age - NCT06762795Recruiting
Gene study for newborns with HIE on cooling therapy
This study uses whole genome sequencing to look at the genes of newborns with HIE (brain injury from lack of oxygen) who are receiving cooling treatment. The goal is to learn more about how genes may affect recovery and outcomes.
Houston, TexasAges birth–1 year - NCT03053193Recruiting
Testing gene activity to guide breast cancer treatment
This study links breast tumor test results from MammaPrint and optional BluePrint (and full genetic data) with real-world clinical information to understand which new gene activity patterns matter. It may help future patients by improving how doctors use these tests to guide care.
Birmingham, AlabamaAges 18 years+ - NCT06576713Recruiting
Genome and RNA sequencing for genetic diagnosis of early Parkinsonism
This study uses advanced genetic testing (genome and RNA sequencing) to find the genetic causes of Parkinsonism that starts before age 40 or runs in families. If you join, you will provide a blood sample and a small skin biopsy to help researchers understand your condition better.
Strasbourg, Grand EstAges 18 years+ - NCT06546137Recruiting
Registry for inherited heart conditions in Brazil
This study is building a national registry in Brazil to learn more about inherited heart conditions and improve care. If you have a family-related heart disease, you may be able to join and help advance cardiovascular healthcare.
Rio Branco, AcreAges Any age - NCT06362369RecruitingPhase 1/Phase 2
Oral 7HP349 with immunotherapy for advanced solid tumors
This trial tests an experimental oral drug (7HP349) combined with two immunotherapy drugs (ipilimumab and nivolumab) for people with advanced solid tumors. It aims to see if the combination is safe and effective in shrinking tumors.
Aurora, ColoradoAges 18 years+ - NCT06365411Enrolling by invitation
Genomic medicine study for kidney transplant patients
This study looks at the genes of people who have had or will have a kidney transplant. It aims to learn how genetic information might help improve transplant care over time. Participants will give blood, urine, stool, and possibly kidney tissue samples for research.
Westmead, New South WalesAges 18–80 - NCT06211348Recruiting
Genomic sequencing for healthy-looking fetuses
This study looks at the benefits of doing extra genetic testing (genomic sequencing) on samples from routine prenatal tests like CVS or amniocentesis, specifically for pregnancies where the baby appears normal on ultrasound.
San Francisco, CaliforniaAges 18–64 - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT06054230Enrolling by invitation
Genetic sequencing for fetal structural problems
This study offers genetic sequencing to find the cause of certain serious fetal problems, such as structural anomalies, severe growth restriction, or unexplained pregnancy loss after 14 weeks. It aims to help families understand why the issue occurred and guide future care.
San Francisco, CaliforniaAges 18–64 - NCT05990179Recruiting
Screening newborns for rare diseases using genetics
This trial offers free genetic screening for rare diseases in newborns. It aims to find health conditions early so babies can get the right care sooner.
New York, New YorkAges 1 day–1 month - NCT05585684Recruiting
Blood test to guide next cancer treatment choices
This study checks whether a blood test can find tumor genetic changes (called “plasma genomic profiling”) to help choose the best next treatment. It may help your care team decide therapy after your cancer progresses or seems likely to progress soon.
Baltimore, MarylandAges 18 years+ - NCT05906407Recruiting
Genetic-guided treatment planning for high-risk early breast cancer
This study uses tumor genetic testing to help plan more precise treatment for people with early high-risk breast cancer. You may be asked to give a recent tumor sample so researchers can match your cancer features with the best available options.
AugsburgAges 18–80 - NCT05858606Recruiting
Study genes and causes of very short height in children
This study looks at your child’s growth history and performs genetic testing to better understand why some children are very short. It may help researchers identify possible underlying causes and improve care, using blood samples from the child and both parents.
MontpellierAges 4–18 - NCT05714592Recruiting
Optical genome mapping for bone marrow changes in blood cancer
This trial tests whether a special eye-based lab test called optical genome mapping can better detect new (acquired) chromosome changes in people with certain slow-growing blood cancers. It may help doctors choose the right next steps based on what’s happening in the bone marrow.
Amiens, PicardieAges 18 years+ - NCT05652569Recruiting
Genomics-guided treatment plan for metastatic breast cancer
This trial tests a personalized treatment approach for people with metastatic (advanced spread) breast cancer using tumor testing. It may help guide doctors toward better-matched therapies based on genomic (DNA) information from your tumor.
AugsburgAges 14–100 - NCT05528133RecruitingPhase 2
Personalized radiation based on tumor genetics in triple-negative breast cancer
This trial tests whether using tumor “genetics” (information from your biopsy) to guide radiation planning can improve treatment for triple-negative breast cancer. It may help by aiming radiation more precisely while still using standard approaches where needed.
Clearwater, FloridaAges 18 years+ - NCT04968834Recruiting
Collecting children’s and young adults’ blood and marrow for genetic testing
This study collects and stores blood and bone marrow samples from young people with certain blood cancers so doctors can do genetic (“genomic”) testing now and in the future. It may help improve understanding of the disease and support better matching of care for patients.
Hartford, ConnecticutAges Up to 30 years - NCT04528303Recruiting
Genetic testing comparison for long-lasting childhood diarrhea
This study compares two types of genetic tests—whole genome sequencing and whole exome sequencing—to find causes of long-lasting diarrhea in children. It may help doctors diagnose the reason for diarrhea faster, which can guide treatment.
Shanghai, Shanghai MunicipalityAges Up to 6 years - NCT03931707Recruiting
Genetic study of newborns in China
This study collects genetic information from very young newborns to better understand early-life health. Your child’s information may help researchers learn about genetics and future research.
Shanghai, Shanghai MunicipalityAges Up to 4 weeks - NCT02595957Recruiting
Study about how people understand genetic test results
This trial studies what people and families think and understand about genetic test results, especially when results suggest a higher risk for disease. It may also include interviews and follow-up, and in some cases additional family testing if it fits the study’s goals.
Bethesda, MarylandAges 1 month–105 years
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Common questions
- Are there clinical trials for genomics?
- Yes. Clin2 currently lists 270 recruiting genomics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genomics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genomics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.