Clinical trials
Genomics clinical trials
Below are recruiting genomics clinical trials, each written for real people, not researchers. We’re tracking 277 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05196789Recruiting
Genetic testing to diagnose inherited bone marrow failure
This study looks at patients with suspected inherited (families-linked) bone marrow failure to better understand the cause using genetic testing. It may help confirm a diagnosis and refine how different inherited conditions are classified.
Melbourne, VictoriaAges 3 months+ - NCT05457140Recruiting
Testing genes and other samples in youth with first psychosis
This study looks at many types of tests (including genetic testing and other lab data) to help understand what may be causing first-time psychosis symptoms in youth. It may help doctors learn more about the condition for future care, and it can involve analyzing family genetic information.
San Diego, CaliforniaAges 7–17 - NCT05471232Recruiting
Genomic testing for youth mental health crises with IDD
This study looks at genetic (DNA) information to understand mental health crises in youth with intellectual and developmental disabilities. It may help doctors learn why these crises happen and improve how future families are supported.
San Diego, CaliforniaAges 7–17 - NCT05528133RecruitingPhase 2
Personalized radiation based on tumor genetics in triple-negative breast cancer
This trial tests whether using tumor “genetics” (information from your biopsy) to guide radiation planning can improve treatment for triple-negative breast cancer. It may help by aiming radiation more precisely while still using standard approaches where needed.
Clearwater, FloridaAges 18 years+ - NCT05652569Recruiting
Genomics-guided treatment plan for metastatic breast cancer
This trial tests a personalized treatment approach for people with metastatic (advanced spread) breast cancer using tumor testing. It may help guide doctors toward better-matched therapies based on genomic (DNA) information from your tumor.
AugsburgAges 14–100 - NCT05714592Recruiting
Optical genome mapping for bone marrow changes in blood cancer
This trial tests whether a special eye-based lab test called optical genome mapping can better detect new (acquired) chromosome changes in people with certain slow-growing blood cancers. It may help doctors choose the right next steps based on what’s happening in the bone marrow.
Amiens, PicardieAges 18 years+ - NCT05858606Recruiting
Study genes and causes of very short height in children
This study looks at your child’s growth history and performs genetic testing to better understand why some children are very short. It may help researchers identify possible underlying causes and improve care, using blood samples from the child and both parents.
MontpellierAges 4–18 - NCT05906407Recruiting
Genetic-guided treatment planning for high-risk early breast cancer
This study uses tumor genetic testing to help plan more precise treatment for people with early high-risk breast cancer. You may be asked to give a recent tumor sample so researchers can match your cancer features with the best available options.
AugsburgAges 18–80 - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT06253338Recruiting
Genes and radiation protection study for untreated cancer
This study looks at whether your genes can help predict how radiation affects your body. It is for people with head, neck, or chest cancer who have not had any previous cancer treatment.
Essen, Germany / NRWAges 18 years+ - NCT06306521Recruiting
Newborn screening for hundreds of genetic diseases by genome sequencing
This research study tests a new way to screen newborns for hundreds of genetic diseases using a sample of their blood or saliva. It aims to find conditions early so your baby can get the right care sooner.
San Diego, CaliforniaAges 1 day–4 weeks - NCT06362369RecruitingPhase 1/Phase 2
Oral 7HP349 with immunotherapy for advanced solid tumors
This trial tests an experimental oral drug (7HP349) combined with two immunotherapy drugs (ipilimumab and nivolumab) for people with advanced solid tumors. It aims to see if the combination is safe and effective in shrinking tumors.
Aurora, ColoradoAges 18 years+ - NCT06535542Recruiting
Gene testing and digital twins for high cholesterol in Emiratis
This study uses whole genome sequencing and digital twin technology to better understand and manage very high cholesterol in Emirati adults. It aims to identify genetic causes and personalize treatment.
Abu Dhabi, Abu Dhabi EmirateAges 18–55 - NCT06546137Recruiting
Registry for inherited heart conditions in Brazil
This study is building a national registry in Brazil to learn more about inherited heart conditions and improve care. If you have a family-related heart disease, you may be able to join and help advance cardiovascular healthcare.
Rio Branco, AcreAges Any age - NCT06762795Recruiting
Gene study for newborns with HIE on cooling therapy
This study uses whole genome sequencing to look at the genes of newborns with HIE (brain injury from lack of oxygen) who are receiving cooling treatment. The goal is to learn more about how genes may affect recovery and outcomes.
Houston, TexasAges birth–1 year - NCT06775561Recruiting
Study of hidden DNA causes for rare neuromuscular and epilepsy diseases
This study is for people with a neuromuscular disease or epilepsy whose genetic testing hasn't found a clear answer. It uses advanced techniques to look at parts of the DNA that don't code for proteins, to find hidden causes and help guide future treatments.
BolognaAges Any age - NCT06894823Recruiting
Precision oncology platform for patients in central-southern Italy
This trial creates a program to offer personalized cancer care for patients living in central-southern Italy. It aims to use your tumor's genetic information to find the best treatment.
NaplesAges Any age - NCT06948344Recruiting
Genetics study for inherited heart muscle disease
This study is looking for people with inherited heart muscle disease that may be genetic. It uses advanced genetic testing to better understand the cause.
SeoulAges 19 years+ - NCT06999096Recruiting
Long-read gene testing for inherited movement disorders
This study uses a new DNA reading method to find hidden genetic causes of dystonia. It is for people with dystonia who had standard genetic testing that did not find a cause.
MontpellierAges Any age - NCT01087320Recruiting
Genetic testing study to find causes of rare disorders
This study uses genome (DNA) sequencing to look for the genetic cause of rare disorders, especially when the cause is unknown. It may help some families better understand what is driving the condition, using genetic information from the affected person and often their parents.
Bethesda, MarylandAges 4 weeks–99 years - NCT02288676Recruiting
Genetic testing to help diagnose ovarian or uterine cancer earlier
This study tests genetic (DNA) information to help doctors identify ovarian or uterine (endometrial) cancer sooner. You may be asked to do this around the time of planned surgery, when tissue is removed and can be checked for genetic clues.
Montreal, QuebecAges 18 years+ - NCT06762678Recruiting
Studying genes in neurodevelopmental disorders with birth defects
This study is for children or adults with neurodevelopmental conditions and unusual physical features, where standard genetic tests haven't found a cause. Researchers will use RNA and DNA sequencing to look for hidden genetic explanations, which could guide better care.
AngersAges Any age - NCT00001373Recruiting
Understanding the genetics of autoinflammatory diseases
This study collects genetic samples and medical histories from people with autoinflammatory diseases (like Familial Mediterranean Fever), their relatives, and healthy volunteers to understand how these conditions run in families and what causes them. Participation mainly involves providing a mail-in DNA sample.
Washington D.C., District of ColumbiaAges 2 months–115 years - NCT05657405Recruiting
Study of data analytics for people with genetic conditions
This is an observational study that collects health and family history information to see how advanced data analysis can help people with genetic conditions. It may involve website forms, optional conversations, and sometimes an NIH visit, depending on your situation.
Bethesda, MarylandAges 1 day–120 years
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Common questions
- Are there clinical trials for genomics?
- Yes. Clin2 currently lists 277 recruiting genomics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a genomics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a genomics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.