Clinical trials
Germ Cell Tumor clinical trials
Below are recruiting germ cell tumor clinical trials, each written for real people, not researchers. We’re tracking 53 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05124951RecruitingPhase 2
Tested a treatment for specific brain germ cell tumors
This Phase 2 trial studies WVI for children and young adults with a newly diagnosed germ cell tumor in one side of the basal ganglia/thalamus. It aims to see how well the treatment works for tumors without spread within the brain.
BeijingAges 3–30 - NCT05455918RecruitingPhase 2
Chemo with paclitaxel, ifosfamide, and cisplatin for high-risk germ cell tumors
This Phase 2 trial tests a specific chemotherapy combination (paclitaxel, ifosfamide, and cisplatin) for children and teens with newly diagnosed, high-risk germ cell tumors. It aims to improve outcomes by treating cancer cells with a stronger chemo plan.
SeoulAges 1–20 - NCT05672043Recruiting
Study genetic risks in children with malignant brain tumors
This study looks at genetic (DNA/molecular) features of malignant brain tumors in children. It may help doctors better understand tumor risk patterns and guide future treatment planning.
Beijing, Beijing MunicipalityAges birth–18 years - NCT02429687RecruitingPhase 3
Testing two chemo regimens for ovarian germ cell tumors
This Phase 3 trial compares two different chemotherapy approaches for women with ovarian sex cord–stromal germ cell tumors. It aims to see which treatment works better and is safer for newly diagnosed stage IIA to IVB disease after surgery.
Jinan, ShandongAges 14–65 - NCT06421805Recruiting
Mediastinal Tumor Patient Database Study
This study is building a database of people with mediastinal tumors. It will collect health information over time to help doctors better understand these tumors and improve care.
Beijing, Beijing MunicipalityAges Any age - NCT07847190RecruitingPhase 2
Adding paclitaxel to standard chemotherapy for tough testicular cancer
This trial tests if adding a drug called paclitaxel to the standard chemotherapy combination (BEP) can improve outcomes for people with aggressive testicular cancer. It is for those whose tumor markers did not drop as fast as expected after the first round of chemo.
MoscowAges 16 years+ - NCT07705035RecruitingPhase 1
DBC-664 for adults with advanced solid tumors
This trial tests a new drug called DBC-664 for people with solid tumors that have come back or spread and cannot be removed by surgery. It may be an option if you have tried other treatments or if standard options are limited.
Denver, ColoradoAges 18 years+ - NCT05889585Recruiting
Life after germ cell cancer treatment side effects study
This study looks at long-term health problems and quality of life in people who survived germ cell tumors after strong chemotherapy with a stem cell transplant or other standard treatments. It may help doctors understand which late side effects are most common and how to better support survivors.
VillejuifAges 18 years+ - NCT07662018Recruiting
Study of stem cell transplant after chemo for children with germ cell tumors
This study looks at how well a stem cell transplant works after a specific combination of chemotherapy drugs (gemcitabine, docetaxel, melphalan, and carboplatin) in children and young adults up to age 21 whose germ cell tumors have come back or not responded to treatment. It may help doctors understand who benefits most from this approach.
Houston, TexasAges 21 years+ - NCT07628634RecruitingEarly Phase 1
Testing a Low-Methionine Diet in Solid Tumor Patients
This early-stage study explores whether eating a diet low in methionine (a natural amino acid found in protein) might help people with advanced solid tumors. Researchers will track how this dietary change affects blood levels and may improve treatment outcomes alongside standard cancer care.
Orange, CaliforniaAges 18 years+ - NCT07614620Recruiting
Hypnosis to reduce anxiety and chemo side effects in young cancer patients
This study tests whether hypnosis (a relaxed, focused mental state) can help young people with sarcoma, germ cell tumors, or breast cancer manage anxiety and reduce side effects from chemotherapy. The trial takes place at Institut Bergonié in France.
BordeauxAges 15–49 - NCT07463508Recruiting
Bile acids as markers for testicular germ cell tumors
This study looks at whether levels of bile acids (substances made by your liver) can help doctors understand how testicular germ cell tumors grow and how they respond to treatment. It may help improve future care for people with this type of cancer.
Clermont-FerrandAges 18 years+ - NCT07453082Recruiting
A study on miRNA371 for newly diagnosed germ cell tumors
This study is looking at a new marker called miRNA371 in people newly diagnosed with germ cell tumors. The goal is to see if it can help predict relapse and guide treatment decisions.
Candiolo, TurinAges 18 years+ - NCT07401316Recruiting
Tracking germ cell tumors with a blood test for cancer DNA
This trial looks for signs of cancer DNA in your blood (circulating tumor DNA) to see if it can help track germ cell tumors. It may help doctors find out if your cancer is coming back earlier.
Indianapolis, IndianaAges 18 years+ - NCT07218913RecruitingPhase 1
Testing a drug to reduce ear damage from chemo in testicular cancer
This trial tests whether adding Pedmark (sodium thiosulfate) to cisplatin chemotherapy can protect hearing in men with stage II or III testicular germ cell tumors. It aims to reduce the risk of drug-related ear damage while still treating the cancer.
Duarte, CaliforniaAges 18 years+ - NCT07188441RecruitingPhase 2
Treating newly diagnosed central malignant germ cell tumors with teniposide and cisplatin
This trial tests a combination of two chemotherapy drugs—teniposide and cisplatin—for people who have just been diagnosed with a malignant germ cell tumor in the brain. The goal is to see if this treatment is safe and effective.
Guangzhou, GuangdongAges 5 years+ - NCT07164313RecruitingPhase 1
ZW251 for advanced solid tumors
This trial is testing a new drug called ZW251 for people with advanced liver cancer (hepatocellular carcinoma), non-small cell lung cancer, or germ cell tumors that have spread or cannot be removed by surgery. It aims to see if the drug is safe and effective.
San Francisco, CaliforniaAges 18 years+ - NCT05705687Recruiting
Testing a treatment plan for higher-risk testicular cancer
This trial checks whether a specific treatment approach works better for men with higher-risk non-seminomatous germ-cell tumors that have spread. Doctors will use tumor marker changes and where the cancer started (often the chest area) to help guide treatment choices.
VillejuifAges 16 years+ - NCT07121322RecruitingPhase 2
Dornase Alfa and Cisplatin for resistant germ cell cancer
This trial tests a combination of two drugs, dornase alfa and cisplatin, for men with germ cell cancer that has not responded to standard treatments or has come back. The goal is to see if this new combination can shrink tumors or stop them from growing.
BratislavaAges 18 years+ - NCT06967961Recruiting
Looking for cancer cells that carry two markers in the blood
This trial is studying a special type of cell that shows up in the blood of people with certain advanced cancers. It aims to find out if these cells can help doctors better understand the cancer and guide treatment.
ToulouseAges 18 years+ - NCT05874063RecruitingPhase 3
Preventing blood clots during first chemotherapy for germ cell tumors
This Phase 3 study tests whether giving enoxaparin (a blood thinner) can prevent dangerous blood clots in people with advanced germ cell tumors starting their first chemotherapy. It is especially focused on people who are at higher risk of clots.
AngersAges 18 years+ - NCT06866964RecruitingPhase 2
Aspirin to prevent blood clots in advanced germ cell cancer chemotherapy
This trial tests if daily aspirin can prevent dangerous blood clots in people receiving chemotherapy for advanced testicular or germ cell cancer. It is for those at high risk of clots and aims to improve safety during treatment.
Charlotte, North CarolinaAges 18–70 - NCT06418789RecruitingPhase 2
High-dose chemo for relapsed germ cell tumors
This trial tests a second-line high-dose chemotherapy for germ cell tumors that have come back after initial treatment. It may be an option for patients whose cancer progressed after 3–4 cycles of standard platinum-based chemo.
Saint Petersburg, Russian FederationAges 18 years+ - NCT06133543Recruiting
Robotic sentinel node biopsy for testicular cancer
This trial uses a robot and a special dye (ICG) to find and remove the first lymph node that might contain cancer cells in men with testicular cancer. It aims to reduce unnecessary lymph node removal while still detecting spread.
DüsseldorfAges 18–99
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Germ Cell Tumor trials by city
Studies with a site in or near these metro areas.
Germ Cell Tumor trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for germ cell tumor?
- Yes. Clin2 currently lists 53 recruiting germ cell tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a germ cell tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a germ cell tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.