Clinical trials
Glioblastoma - Category clinical trials
Below are recruiting glioblastoma - category clinical trials, each written for real people, not researchers. We’re tracking 355 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06072586RecruitingEarly Phase 1
Study of BDTX-1535 for brain tumors with EGFR changes
This trial tests a new drug, BDTX-1535, for people with a type of brain tumor called high-grade glioma that has a specific change in the EGFR gene. The study looks at how the drug works in the body and how safe it is for both newly diagnosed and recurrent tumors.
Chandler, ArizonaAges 18 years+ - NCT07493447RecruitingEarly Phase 1
Imaging dye to help see brain tumors during surgery
This study tests a special dye (panitumumab-IRDye800) that helps surgeons see brain lesions more clearly during surgery. The dye attaches to a protein on cancer cells and lights up under a special camera, which may help remove more tumor safely.
Nashville, TennesseeAges 18 years+ - NCT07708961RecruitingPhase 2
Temozolomide with or without WSD0922-FU for EGFR-mutant glioblastoma
This trial tests whether adding a new drug, WSD0922-FU, to standard chemotherapy (temozolomide) works better than temozolomide alone for a specific type of glioblastoma that has an EGFR mutation. It is for patients who have completed radiation and temozolomide together but haven't started maintenance temozolomide yet.
Scottsdale, ArizonaAges 18 years+ - NCT01906385RecruitingPhase 1/Phase 2
Recurrent brain tumor study testing rhenium nano-liposome
This early-phase study tests a drug made of tiny fat-like particles carrying rhenium for recurrent (coming back) high-grade glioma. It mainly checks safety and the highest tolerable dose, and it also looks for signs the treatment may slow tumor growth.
Manhasset, New YorkAges 18 years+ - NCT03005132Recruiting
Study for people with newly diagnosed brain cancer (GBM)
This trial looks at people with glioblastoma (GBM), a fast-growing brain tumor, to better understand it and how treatments might work. You may be able to join if you’re in a good general health range and have not had prior cancer chemotherapy.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT03787056Recruiting
Blood test marker study in many cancer types
This study measures a blood marker called progastrin (at diagnosis and during treatment) to see how well it predicts response or outcomes. It may help doctors choose or monitor treatment more precisely for several cancer types.
BronAges 18 years+ - NCT04306432Recruiting
Check how cognitive tests change after brain tumor radiation
This trial studies how radiation therapy affects thinking and memory in adults with certain brain tumors. It may help doctors understand which patients are more likely to have cognitive side effects and how to measure them over time.
Copenhagen, Capital RegionAges 18–100 - NCT04708171Recruiting
Compare awake, asleep, or no mapping during brain tumor surgery
This study looks at whether surgeons get better safety and control during glioblastoma removal by using awake testing, asleep testing, or no mapping. Mapping helps identify brain areas involved in movement, speech, or vision to lower the risk of serious side effects.
San Francisco, CaliforniaAges 18–90 - NCT05326334Recruiting
Study gut microbiome in new glioblastoma patients
This trial studies how changes in gut bacteria (gut microbiome) relate to outcomes in people with newly diagnosed glioblastoma receiving standard chemo-radiation. It may help doctors learn which gut-bacteria patterns go along with better or worse results during treatment.
Ottawa, OntarioAges 18 years+ - NCT04443010RecruitingPhase 1/Phase 2
Testing a new protein drug with standard treatment for new glioblastoma
This Phase 1/2 study tests whether adding a drug called L19TNF to standard chemoradiotherapy is safe and may work better than standard treatment alone for newly diagnosed glioblastoma. If you qualify, you would be closely monitored for side effects and treatment response.
ZurichAges 18 years+ - NCT03861299Recruiting
Awake brain surgery versus sleep surgery for glioblastoma
This study compares two ways of doing brain surgery for glioblastoma: doing parts of the operation while you are awake, versus doing it fully under general anesthesia (sleep). It aims to see which approach is safer and better for protecting brain functions like speech and movement while removing the tumor.
GhentAges 18–90 - NCT06146725Recruiting
Resection vs. biopsy in high-grade glioma patients
This study compares whether having surgery to remove as much of the tumor as possible (resection) or just taking a small sample (biopsy) leads to better outcomes for people with a fast-growing brain tumor (high-grade glioma). The goal is to help guide treatment decisions.
San Francisco, CaliforniaAges 18–90 - NCT06146738Recruiting
Palliative care vs. surgery for high-grade glioma patients
This study compares receiving palliative care (supportive treatments) versus surgery (removing the tumor) for people with a high-grade glioma, a fast-growing brain tumor. The goal is to find out which approach improves quality of life and survival.
San Francisco, CaliforniaAges 18–90 - NCT06160596Recruiting
Understanding long-term cancer survival in hard-to-treat tumors
This study looks at why some people with hard-to-treat cancers live much longer than expected. It collects tumor samples to search for clues that might help future patients.
VillejuifAges 18 years+ - NCT02925234RecruitingPhase 2
Basket trial of reused cancer drugs matched to tumor markers
This trial tests cancer drugs that are already approved for other cancers, chosen based on specific changes found in your tumor. It may help people whose cancer is growing despite standard treatment (or who no longer have standard options).
AlkmaarAges 18 years+ - NCT06220552RecruitingPhase 2
Low-dose radiation plus immunotherapy for recurrent glioblastoma
This trial tests a combination of low-dose radiation, an immunotherapy drug (sintilimab), and chemotherapy (temozolomide) for people with glioblastoma that has come back. The goal is to see if this approach can help control the tumor and improve survival.
Zhuhai, GuangdongAges 18 years+ - NCT06001281Recruiting
Blood test to predict treatment response in glioblastoma
This study looks at whether a blood marker called CD146 can help predict how well patients with a recurrent brain tumor (glioblastoma) respond to a treatment called bevacizumab. The goal is to see if this test can help doctors personalize care.
MarseilleAges 18 years+ - NCT07862647RecruitingPhase 1
Targeted light therapy with chemotherapy for newly diagnosed butterfly glioblastoma
This trial tests a new light-based treatment that is given alongside standard chemotherapy and radiation for people with a type of brain tumor called 'butterfly glioblastoma'. The goal is to see if adding this therapy can improve outcomes for patients with this challenging condition.
Buffalo, New YorkAges 18–80 - NCT07865195Recruiting
Study of brain tumors in Réunion island residents
This study gathers information about people diagnosed with a type of brain tumor called diffuse glioma in Réunion island. It aims to better understand the disease, its impact, and the care provided, which may help improve future treatments and support.
Saint-PierreAges Any age - NCT06041555Recruiting
MRI-guided radiotherapy study for five cancer types
This study collects MRI scans and treatment data from patients getting MRI-guided radiotherapy for certain cancers. It aims to improve radiation treatment planning using imaging and biological information.
LyonAges 18 years+ - NCT06118723Recruiting
Supramaximal vs maximal surgery for brain tumors
This trial compares removing as much tumor as safely possible (supramaximal resection) with standard maximal resection in people with high-grade glioma (an aggressive brain tumor). The goal is to see if more extensive removal improves survival and quality of life.
San Francisco, CaliforniaAges 18–90 - NCT06273176Recruiting
Surgery with or without brain mapping for recurrent glioblastoma
This study is testing whether using a special brain-mapping technique during surgery helps people with recurrent glioblastoma. It compares standard surgery to surgery with mapping to see if it leads to better outcomes for tumors near important brain areas.
San Francisco, CaliforniaAges Up to 90 years - NCT06271421Recruiting
Nanoparticle heat therapy for recurrent glioblastoma
This trial tests a new treatment for recurrent glioblastoma using tiny magnetic particles (nanoparticles) that are heated to kill cancer cells. The particles are injected into the tumor, and then a magnetic field device heats them up. It's for people who have already tried standard therapy and whose tumor has come back.
PoznanAges 18 years+ - NCT06283927Recruiting
Surgery vs. medical care for recurrent glioblastoma
This trial compares surgery to the best non-surgical treatment for people whose glioblastoma has come back. The goal is to see which approach helps people live longer with a better quality of life.
San Francisco, CaliforniaAges 18–90
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Common questions
- Are there clinical trials for glioblastoma - category?
- Yes. Clin2 currently lists 355 recruiting glioblastoma - category studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a glioblastoma - category trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a glioblastoma - category trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.