Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06110091Recruiting
Improving nighttime urination and sleep in older veterans
This study aims to improve nighttime urination (nocturia) and sleep in adults 60 and older. It offers a program that combines behavioral techniques for both bladder control and insomnia, with weekly visits at an Atlanta VA clinic.
Los Angeles, CaliforniaAges 60 years+ - NCT06170437Recruiting
Smoke-free Home Study in Subsidized Housing
This study looks at ways to help people who live in subsidized housing make their homes smoke-free. You may be able to join if you are a current smoker and smoke inside your home.
San Francisco, CaliforniaAges 18 years+ - NCT06184646Recruiting
Prunes for bone health in postmenopausal women
This trial tests how many prunes per day can best improve bone health in postmenopausal women. It may help you if you have lower bone density but not severe bone loss.
San Diego, CaliforniaAges Any age - NCT06230510Recruiting
Whole vs. low-fat milk study for toddlers
This study compares the health effects of drinking whole milk versus 1% low-fat milk for one year in children aged 23 to 48 months. Researchers want to see which type of milk is better for growth and overall health.
Oakland, CaliforniaAges 1.9 years–4 years - NCT06286670Recruiting
Comparing one versus two implants for thigh bone breaks
This trial is testing whether using two metal implants to fix a broken thigh bone (near the knee) works better than using just one. It aims to help patients with certain types of fractures that need surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06311214RecruitingPhase 2
Personalized ADC therapy for advanced solid tumors
This trial tests personalized antibody-drug conjugates (ADCs) for advanced solid tumors. It looks for specific proteins on your tumor cells to match you with a treatment that targets them directly.
Duarte, CaliforniaAges 18 years+ - NCT07694544RecruitingPhase 1
Oral EC5026 study in people with kidney disease
This trial tests a medication called EC5026 in people with and without chronic kidney disease (CKD) to see how the body handles it. It helps understand if dose adjustments are needed for people with impaired kidney function.
Sacramento, CaliforniaAges 55 years+ - NCT06340152Recruiting
Studying maternal health after preeclampsia
This trial follows women who have had preeclampsia to learn more about their health after pregnancy. It collects blood and tissue samples to find markers that could improve future care.
San Diego, CaliforniaAges 18–50 - NCT06353997RecruitingPhase 2
New immunotherapy combination before surgery for triple-negative breast cancer
This trial tests a new combination of two immunotherapy drugs (INBRX-106 and pembrolizumab) given before surgery for people with early-stage triple-negative breast cancer. The goal is to see if this treatment can shrink the tumor and improve outcomes.
Los Angeles, CaliforniaAges 18 years+ - NCT06380517RecruitingPhase 3
Headset therapy vs patching for lazy eye in children
This study tests a new way to treat lazy eye (amblyopia) in 4 to 7 year olds using special shows watched through a headset (dichoptic therapy). It compares this to the standard treatment of wearing a patch over the stronger eye. The goal is to see if the headset therapy works as well or better than patching.
Los Angeles, CaliforniaAges 4–7 - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
La Jolla, CaliforniaAges 21–75 - NCT06415721Recruiting
TMS guided by brain scans for alcohol use disorder
This study uses a brain stimulation technique called TMS combined with MRI scans to treat alcohol use disorder. It aims to see if targeting specific brain connections can help reduce drinking.
Palo Alto, CaliforniaAges 25–75 - NCT06418204Recruiting
Cannabis use study for cancer patients in community clinics
This study looks at the benefits and risks of using cannabis or cannabinoids for cancer patients. It aims to help understand how these products affect symptoms and quality of life during chemotherapy or immunotherapy.
Fresno, CaliforniaAges 18 years+ - NCT06421350Recruiting
Closed-loop spinal cord stimulation for complex regional pain syndrome
This trial tests a new type of spinal cord stimulator that automatically adjusts to your pain signals. It may help people with complex regional pain syndrome (CRPS) who have not tried this kind of therapy before.
La Jolla, CaliforniaAges 18 years+ - NCT06422455Recruiting
Genetic testing for underserved cancer patients
This study offers free genetic testing to cancer patients and their healthcare providers. It aims to help people who may not have easy access to genetic testing understand their cancer risk.
Los Angeles, CaliforniaAges 18 years+ - NCT06480578RecruitingPhase 2
Sensor pill study to improve HIV medication adherence
This study tests a special pill that has a sensor inside, which sends information to your doctor or care team to help you remember to take your HIV medication. It is for people who sometimes miss doses and want extra support.
Los Angeles, CaliforniaAges 18 years+ - NCT06856057Recruiting
Support for caregivers and kids after injury
This study helps parents and young children cope with stress after a hospital stay for an injury. It tests a program to improve mental health for both caregivers and kids.
Los Angeles, CaliforniaAges 18 years+ - NCT06995378Recruiting
Study on prediabetes risk tools at UCLA
This study tests a tool that uses your electronic health records to identify older adults with prediabetes. It aims to help doctors better manage risk and prevent diabetes.
Los Angeles, CaliforniaAges 65 years+ - NCT07694206Recruiting
Digital and blood tests for delirium in the ICU
This trial studies whether digital tools and blood tests can help detect delirium (sudden confusion) in ICU patients. If you or your loved one is in the ICU, this research could lead to better monitoring and care.
La Jolla, CaliforniaAges 65 years+ - NCT06486688Recruiting
Virtual program to help teens with substance use risk
This trial tests a virtual program integrated into pediatric check-ups to help teens at risk for alcohol or drug problems. It aims to identify teens who may need extra support and connect them with helpful resources.
Pleasanton, CaliforniaAges 12–17 - NCT06524882RecruitingPhase 3
Special glasses for lazy eye in children 8 to 12 years old
This trial tests if special movies or games viewed through a headset can improve vision in children with lazy eye (amblyopia). It compares these treatments to wearing glasses alone.
San Francisco, CaliforniaAges 8–12 - NCT06535789RecruitingPhase 2/Phase 3
Inhaled insulin vs injections for gestational diabetes
This trial compares an inhaled insulin (Afrezza) to insulin injections for managing blood sugar after meals in women with gestational diabetes. The goal is to see if the inhaled option works as well and is easier to use.
Santa Barbara, CaliforniaAges 18–40 - NCT06562127Recruiting
Water exercise and cognitive training for veterans with TBI
This trial tests if combining water-based exercise with cognitive training over eight months can help improve thinking and memory in veterans with a past mild or moderate brain injury. It may benefit veterans aged 50-89 who have ongoing cognitive complaints.
San Francisco, CaliforniaAges 50–89 - NCT06565065Recruiting
Boost your immune system with gentle bodywork
This study tests whether a gentle hands-on technique called lymphatic osteopathic manipulative treatment (OMT) can help improve immune function in healthy adults. You would attend three visits where we do the treatment, take blood samples, and ask you to avoid certain activities beforehand.
Pomona, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- University of California, Davis Medical Center · 3 studies
- University of California, San Francisco · 3 studies
- Western University of Health Sciences · 3 studies
- Children's Hospital Los Angeles · 2 studies
- Scripps Health · 2 studies
- Stanford University · 2 studies
- UC Irvine Health · 2 studies
- Univ. of California- Berkeley · 2 studies
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.