Clinical trials · California
Health clinical trials in California
We’re tracking 342 recruiting health studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06654752Recruiting
Simpler treatment for lung flare-ups in kids with CF
This study tests a streamlined approach to managing sudden lung symptoms (pulmonary exacerbations) in children with cystic fibrosis. It aims to see if a simpler treatment plan works as well as standard care, which could mean less time in the hospital and fewer disruptions to daily life.
Los Angeles, CaliforniaAges 3–18 - NCT06650163RecruitingPhase 1
New imaging test for brain tumor surgery planning
This trial tests a new kind of PET scan that uses a special tracer (Zr-89 crefmirlimab berdoxam) to help doctors see brain tumors more clearly before surgery. If you are scheduled to have your brain tumor removed, this scan may give your surgeon extra information to guide the operation.
Los Angeles, CaliforniaAges 18 years+ - NCT06651086Recruiting
Executive functioning help for children in therapy
This study tests a new way to help children with executive functioning challenges (like planning and staying organized) in therapy. It's for kids ages 6-12, with or without autism, who are getting therapy at publicly funded clinics.
San Diego, CaliforniaAges 6–99 - NCT06605404Recruiting
Pan-tumor study of a blood test after cancer surgery
This study is testing a new blood test that looks for leftover cancer cells after surgery. It is for people with different types of solid tumors who are planning to have surgery to cure their cancer. The goal is to see if the test can help guide future treatment decisions.
Glendale, CaliforniaAges 18 years+ - NCT06605014Recruiting
Body alignment after stroke or mini-stroke
This study looks at how a stroke or mini-stroke affects the body's natural movement and alignment (called somatic dysfunction). Researchers want to see if there are common patterns of tightness or imbalance after a stroke, which could help guide future treatments.
Sacramento, CaliforniaAges 18 years+ - NCT06590285Recruiting
Better ways to manage bone marrow transplant care
This study tests a smartphone app to help patients and doctors manage care during a bone marrow transplant. If you are planning a transplant, the app may give you clear guidance and education.
San Diego, CaliforniaAges 18 years+ - NCT06598436Recruiting
Digital coaching for better diabetes or blood pressure control
This study offers a digital health coaching program to help people with poorly controlled diabetes or high blood pressure manage their condition. It works through telehealth tools and is designed for patients at San Francisco Health Network primary care clinics.
San Francisco, CaliforniaAges 18 years+ - NCT05697328Recruiting
Testing barotrauma effects of hyperbaric oxygen
This study looks at problems caused by pressure changes during hyperbaric oxygen therapy (HBOT). It may help the team understand risks and how to keep treatment safer while you get HBOT.
Walnut Creek, CaliforniaAges 18 years+ - NCT06581146Recruiting
Liver health study for boys with XLMTM
This study looks at how the liver works in boys with a serious muscle condition called XLMTM. It checks whether their liver is healthy, which may help doctors better understand the condition and guide future treatments.
Santa Monica, CaliforniaAges Up to 17 years - NCT06569303Recruiting
Filipino family health study for parents of children 8–12
This study offers a free parenting program for Filipino families with children ages 8–12 to help strengthen family bonds and manage challenges together. It is designed to understand what works best for your community.
Pasadena, CaliforniaAges 8 years+ - NCT06574191Recruiting
Knee osteoarthritis study: pain and health outcomes
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
Sacramento, CaliforniaAges 50 years+ - NCT06581484Recruiting
Improving care for adults with congenital heart disease
This study aims to improve care for adults with congenital heart disease. If you join, researchers will work to better understand your needs and help enhance your treatment.
San Francisco, CaliforniaAges 18 years+ - NCT06575296RecruitingPhase 1
Revumenib after stem cell transplant for acute leukemia
This trial tests a drug called revumenib to help keep leukemia from coming back after a stem cell transplant. It is for people with specific genetic types of acute leukemia who have recently had or will soon have a transplant.
Duarte, CaliforniaAges 2 years+ - NCT04736667Recruiting
Screening survey for mitral valve treatment planning
This study is for people who did not pass an initial screening for a specific mitral valve procedure called TMVI. It may help the team understand screening results and improve how patients are assessed for the right next steps.
Los Angeles, CaliforniaAges 18 years+ - NCT04199676Recruiting
Testing blood sugar after delivery for gestational diabetes
This study checks your blood sugar shortly after birth (on day 0 or day 1) to see how well glucose testing works for people who had gestational diabetes. The results may help guide follow-up care and reduce the risk of longer-term blood sugar problems.
Long Beach, CaliforniaAges 18 years+ - NCT06524882RecruitingPhase 3
Special glasses for lazy eye in children 8 to 12 years old
This trial tests if special movies or games viewed through a headset can improve vision in children with lazy eye (amblyopia). It compares these treatments to wearing glasses alone.
Anaheim, CaliforniaAges 8–12 - NCT06518057RecruitingPhase 2
Sparing memory during brain radiation for leptomeningeal metastases
This trial tests a special type of radiation that avoids the memory center of the brain (the hippocampus) while treating cancer that has spread to the lining of the brain and spinal cord. It may help reduce side effects on thinking and memory for people with breast or lung cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06513962RecruitingPhase 3
Triptorelin to protect ovaries in young women with cancer
This study tests whether a medicine called triptorelin can protect the ovaries in young women and teens receiving strong chemotherapy for cancer. If you are newly diagnosed with a cancer (other than breast cancer) and are about to get certain chemotherapy drugs, this trial may help preserve your fertility.
Los Angeles, CaliforniaAges Up to 39 years - NCT06508164Recruiting
International registry for rare RYR2 variants
This study creates a registry for people with rare changes in the RYR2 gene that affect heart function. Researchers will collect information to better understand these conditions and improve care.
San Francisco, CaliforniaAges Any age - NCT06480578RecruitingPhase 2
Sensor pill study to improve HIV medication adherence
This study tests a special pill that has a sensor inside, which sends information to your doctor or care team to help you remember to take your HIV medication. It is for people who sometimes miss doses and want extra support.
Los Angeles, CaliforniaAges 18 years+ - NCT06476795Recruiting
Grape pomace from chardonnay for heart and gut health in postmenopausal women
This study tests if consuming a powder made from chardonnay grape pomace (the leftover skins and seeds from winemaking) can improve gut and heart health in postmenopausal women. You may be a good fit if you are between 45-70, have gone through menopause, and have higher levels of blood fats called triglycerides.
Davis, CaliforniaAges 45–70 - NCT06422455Recruiting
Genetic testing for underserved cancer patients
This study offers free genetic testing to cancer patients and their healthcare providers. It aims to help people who may not have easy access to genetic testing understand their cancer risk.
Los Angeles, CaliforniaAges 18 years+ - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT06421350Recruiting
Closed-loop spinal cord stimulation for complex regional pain syndrome
This trial tests a new type of spinal cord stimulator that automatically adjusts to your pain signals. It may help people with complex regional pain syndrome (CRPS) who have not tried this kind of therapy before.
La Jolla, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- Stanford University · 3 studies
- City of Hope · 2 studies
- UC Davis Health · 2 studies
- University of California, Davis · 2 studies
- University of California, San Francisco · 2 studies
- Children's Hospital of Los Angeles & Anton Yelchin Cystic Fibrosis Clinic
- Children's Hospital of Orange County
- John Muir Health
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 342 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.