Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06569303Recruiting
Filipino family health study for parents of children 8–12
This study offers a free parenting program for Filipino families with children ages 8–12 to help strengthen family bonds and manage challenges together. It is designed to understand what works best for your community.
Pasadena, CaliforniaAges 8 years+ - NCT06572605RecruitingPhase 1/Phase 2
Radiation plus talquetamab for myeloma outside the bone
This trial tests combining radiation therapy with a targeted drug called talquetamab for multiple myeloma that has formed tumors outside the bone (extramedullary disease). It aims to see if this combination can shrink or control these tumors and improve outcomes.
Duarte, CaliforniaAges 18 years+ - NCT06574191Recruiting
Knee osteoarthritis study: pain and health outcomes
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
Sacramento, CaliforniaAges 50 years+ - NCT06575296RecruitingPhase 1
Revumenib after stem cell transplant for acute leukemia
This trial tests a drug called revumenib to help keep leukemia from coming back after a stem cell transplant. It is for people with specific genetic types of acute leukemia who have recently had or will soon have a transplant.
Duarte, CaliforniaAges 2 years+ - NCT06581484Recruiting
Improving care for adults with congenital heart disease
This study aims to improve care for adults with congenital heart disease. If you join, researchers will work to better understand your needs and help enhance your treatment.
San Francisco, CaliforniaAges 18 years+ - NCT06598436Recruiting
Digital coaching for better diabetes or blood pressure control
This study offers a digital health coaching program to help people with poorly controlled diabetes or high blood pressure manage their condition. It works through telehealth tools and is designed for patients at San Francisco Health Network primary care clinics.
San Francisco, CaliforniaAges 18 years+ - NCT06139627Recruiting
Geriatric assessment for older adults with lung cancer getting chemotherapy and radiation
This trial tests whether a special geriatric assessment can help manage side effects for adults aged 60 and older with non-small cell lung cancer who are starting a new treatment plan that includes chemotherapy and radiation. It aims to improve quality of life and treatment outcomes.
Duarte, CaliforniaAges 60 years+ - NCT07020533RecruitingPhase 1
CMV vaccine for stem cell transplant recipients
This trial tests a vaccine designed to boost immunity against CMV (a common virus) and prevent active CMV infection in people receiving a half-matched stem cell transplant. It may help protect you from CMV-related complications after transplant.
Duarte, CaliforniaAges 18–75 - NCT06605014Recruiting
Body alignment after stroke or mini-stroke
This study looks at how a stroke or mini-stroke affects the body's natural movement and alignment (called somatic dysfunction). Researchers want to see if there are common patterns of tightness or imbalance after a stroke, which could help guide future treatments.
Sacramento, CaliforniaAges 18 years+ - NCT06605404Recruiting
Pan-tumor study of a blood test after cancer surgery
This study is testing a new blood test that looks for leftover cancer cells after surgery. It is for people with different types of solid tumors who are planning to have surgery to cure their cancer. The goal is to see if the test can help guide future treatment decisions.
San Diego, CaliforniaAges 18 years+ - NCT06650163RecruitingPhase 1
New imaging test for brain tumor surgery planning
This trial tests a new kind of PET scan that uses a special tracer (Zr-89 crefmirlimab berdoxam) to help doctors see brain tumors more clearly before surgery. If you are scheduled to have your brain tumor removed, this scan may give your surgeon extra information to guide the operation.
Los Angeles, CaliforniaAges 18 years+ - NCT06651086Recruiting
Executive functioning help for children in therapy
This study tests a new way to help children with executive functioning challenges (like planning and staying organized) in therapy. It's for kids ages 6-12, with or without autism, who are getting therapy at publicly funded clinics.
San Diego, CaliforniaAges 6–99 - NCT06654752Recruiting
Simpler treatment for lung flare-ups in kids with CF
This study tests a streamlined approach to managing sudden lung symptoms (pulmonary exacerbations) in children with cystic fibrosis. It aims to see if a simpler treatment plan works as well as standard care, which could mean less time in the hospital and fewer disruptions to daily life.
Los Angeles, CaliforniaAges 3–18 - NCT06660758Recruiting
Pilot study of Entarik device in healthy adults
This study tests a new version of the Entarik system, a device that goes through a feeding tube, in healthy adults. It helps researchers see if the system works safely and as intended.
Berkeley, CaliforniaAges 18 years+ - NCT06661538RecruitingPhase 2
Food referrals to help children with health conditions
This study tests a program that helps families with food insecurity get connected to food resources. It is for children ages 5–18 who are already seen at certain specialty clinics and who receive Medicaid or SNAP.
San Diego, CaliforniaAges 5 years+ - NCT06699056Recruiting
AI heart monitor study for ejection fraction
This study uses an AI-powered wearable monitor to check how well your heart pumps blood (ejection fraction) from a simple EKG recording. It may help doctors quickly assess heart function without extra tests.
Orange, CaliforniaAges 18 years+ - NCT06706752Recruiting
Shengbai oral formula for chemotherapy side effects
This study tests if a Chinese herbal formula called Shengbai can safely reduce side effects from chemotherapy. It might help you feel better during cancer treatment.
Oakland, CaliforniaAges 18–80 - NCT04765150Recruiting
AI helps classify prostate cancer using MRI images
This trial studies whether a computer (AI) can better sort MRI results to improve prostate cancer diagnosis or classification. You may benefit by getting your multi-part MRI looked at in a new, more precise way, while helping researchers refine decision-making.
Los Angeles, CaliforniaAges 18 years+ - NCT05685745Recruiting
Hospital data collection for very early baby care
This study collects information from hospitals about babies born extremely early (22 to 23 weeks of pregnancy). It helps researchers understand what care happens and what outcomes occur, which can guide improvements in future care.
Orange, CaliforniaAges birth–1 year - NCT07686913Recruiting
Steri-Strips vs standard closure for C-section incisions
This study compares using Steri-Strips (a special type of tape) to close the C-section incision versus the standard method. The goal is to see which way helps the wound heal better.
Moreno Valley, CaliforniaAges 18 years+ - NCT06724172Recruiting
Comparing health programs for pregnant mothers from diverse backgrounds
This study tests two different health programs for pregnant women to see which one helps mothers and babies more. You may join if you are early in your pregnancy, identify as Black, Hispanic, or have Medicaid, and speak English or Spanish.
Palo Alto, CaliforniaAges 18 years+ - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Los Angeles, CaliforniaAges 13–29 - NCT06738537Recruiting
Choosing treatment for mitral valve prolapse
This study looks at how to involve you in decisions about treating mitral valve prolapse, a condition where a heart valve doesn't close tightly. It aims to find the best way to help you and your doctor choose the right treatment.
Los Angeles, CaliforniaAges 21 years+ - NCT06741865Recruiting
Helping older adults keep their minds sharp (INSPIRE-Faith)
This trial tests whether certain lifestyle and thinking exercises help preserve memory and brain function in older adults, especially in the African American community. You may join if you are 55 or older and your memory is normal or mildly impaired.
Los Angeles, CaliforniaAges 55–85
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- City of Hope Comprehensive Cancer Center · 4 studies
- Rady Children's Hospital San Diego · 2 studies
- Stanford University · 2 studies
- UCLA / Jonsson Comprehensive Cancer Center · 2 studies
- University of California, Davis Medical Center · 2 studies
- Cedars-Sinai Medical Center
- Children's Hospital Los Angeles
- Children's Hospital Orange County
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.