Clinical trials · California
Health clinical trials in California
We’re tracking 342 recruiting health studies with a site in California — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT04314375RecruitingPhase 4
Budesonide tablets for children with mild to moderate ulcerative colitis
This trial studies whether budesonide extended-release tablets are safe and effective for improving symptoms in children ages 5–17 with active, mild to moderate ulcerative colitis. It also measures how the medicine moves through the body.
Garden Grove, CaliforniaAges 5–17 - NCT06410209RecruitingPhase 2
Walking Juntos: Smartphone program to help Hispanic cancer survivors be active
This study will test if a smartphone program and social media group can help Hispanic/Latino teens and young adults who had childhood cancer become more physically active. You would wear a Fitbit and use a phone app with culturally tailored tips and support.
Downey, CaliforniaAges 15–20 - NCT06418204Recruiting
Cannabis use among cancer patients in community clinics
This study looks at how cancer patients use cannabis (marijuana) and cannabis products to manage symptoms during chemotherapy or immunotherapy. The goal is to learn about the benefits and risks so doctors can better guide patients.
Antioch, CaliforniaAges 18 years+ - NCT06399861Recruiting
Humidity in incubators for very premature babies
This study looks at how different humidity levels in incubators affect very premature babies born before 25 weeks of pregnancy. It aims to find the best conditions to help their delicate skin and overall health.
San Diego, CaliforniaAges birth–1 day - NCT06380517RecruitingPhase 3
Headset therapy vs patching for lazy eye in children
This study tests a new way to treat lazy eye (amblyopia) in 4 to 7 year olds using special shows watched through a headset (dichoptic therapy). It compares this to the standard treatment of wearing a patch over the stronger eye. The goal is to see if the headset therapy works as well or better than patching.
Berkeley, CaliforniaAges 4–7 - NCT06353997RecruitingPhase 2
Neoadjuvant INBRX-106 with pembrolizumab for early-stage triple-negative breast cancer
This trial tests whether adding an experimental drug called INBRX-106 to the standard immunotherapy (pembrolizumab) and chemotherapy before surgery can improve outcomes for patients with early-stage triple-negative breast cancer. The goal is to shrink the tumor and potentially reduce the risk of the cancer coming back.
Los Angeles, CaliforniaAges 18 years+ - NCT06311214RecruitingPhase 2
Personalized ADC therapy for advanced solid tumors
This trial tests personalized antibody-drug conjugates (ADCs) for advanced solid tumors. It looks for specific proteins on your tumor cells to match you with a treatment that targets them directly.
Encinitas, CaliforniaAges 18 years+ - NCT06286670Recruiting
Comparing one versus two implants for thigh bone breaks
This trial is testing whether using two metal implants to fix a broken thigh bone (near the knee) works better than using just one. It aims to help patients with certain types of fractures that need surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
San Diego, CaliforniaAges 6 years+ - NCT06249126Recruiting
Heel bone fusion for severe fractures
This trial tests whether fusing the joint just below the ankle (subtalar joint) during heel bone fracture repair helps people with severe fractures heal better. You may qualify if you have a specific type of broken heel bone and can return for follow-up visits for one year.
Orange, CaliforniaAges 18 years+ - NCT06233344RecruitingPhase 2
Mindfulness and psilocybin study for healthy adults
This study tests whether combining mindfulness training with a single dose of psilocybin (a psychedelic found in certain mushrooms) can help healthy adults. It aims to explore how these two approaches together might improve well-being.
Los Angeles, CaliforniaAges 25 years+ - NCT06230510Recruiting
Whole vs. low-fat milk study for toddlers
This study compares the health effects of drinking whole milk versus 1% low-fat milk for one year in children aged 23 to 48 months. Researchers want to see which type of milk is better for growth and overall health.
Oakland, CaliforniaAges 1.9 years–4 years - NCT06184646Recruiting
Prunes for bone health in postmenopausal women
This trial tests how many prunes per day can best improve bone health in postmenopausal women. It may help you if you have lower bone density but not severe bone loss.
San Diego, CaliforniaAges Any age - NCT06188689Recruiting
Testing a new diagnostic test for heart rhythm disorders
This study is evaluating a new diagnostic test for Calcium Release Deficiency Syndrome (CRDS) and related heart rhythm disorders. It aims to find out if this test can accurately identify patients with these conditions, which could lead to better diagnosis and treatment.
San Francisco, CaliforniaAges Any age - NCT06177717Recruiting
Lung Health Study for Young Adults
This study looks at how young adults' lungs work over time. It is a research visit where you'll complete breathing and other health tests to help understand lung health in people aged 25–35.
Los Angeles, CaliforniaAges 25–35 - NCT06139627Recruiting
Geriatric assessment for older adults with lung cancer getting chemotherapy and radiation
This trial tests whether a special geriatric assessment can help manage side effects for adults aged 60 and older with non-small cell lung cancer who are starting a new treatment plan that includes chemotherapy and radiation. It aims to improve quality of life and treatment outcomes.
Duarte, CaliforniaAges 60 years+ - NCT06110091Recruiting
Improving nighttime urination and sleep in older veterans
This study aims to improve nighttime urination (nocturia) and sleep in adults 60 and older. It offers a program that combines behavioral techniques for both bladder control and insomnia, with weekly visits at an Atlanta VA clinic.
Los Angeles, CaliforniaAges 60 years+ - NCT06107842Recruiting
Exercise program for older veterans' memory and thinking
This study tests whether an exercise program called Gerofit can help improve memory and thinking in older Veterans. If you join, you will take part in supervised exercise sessions to see how it affects your brain health.
West Los Angeles, CaliforniaAges 65 years+ - NCT06082453Recruiting
Modernizing syphilis testing in pregnancy and beyond
This study is testing a new, faster way to check for syphilis in pregnant people, new mothers, and their newborns, as well as in men and non-pregnant people at a Harris Health clinic. The goal is to make sure more people get the right treatment quickly.
Los Angeles, CaliforniaAges Up to 45 years - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT06064097RecruitingPhase 2
Nivolumab plus chemo for young people with nasopharyngeal cancer
This trial tests combining the immunotherapy drug nivolumab with standard chemotherapy to treat newly diagnosed nasopharyngeal cancer in children and young adults. The goal is to see if adding this immune-boosting medicine can help shrink tumors and prevent the cancer from coming back.
Downey, CaliforniaAges Up to 21 years - NCT06046651Recruiting
Blood sample collection for lab research
This study collects blood samples from healthy adults to help researchers learn more about how to run lab tests. It involves one visit or at-home collection and might help future medical research.
San Francisco, CaliforniaAges 18 years+ - NCT06022965Recruiting
Telemedicine support for older adults with cancer
This study uses telemedicine (video or phone visits) to help older adults with cancer, especially those in underserved communities, get better care. If you're 65 or older and starting a new cancer treatment, you may be able to join from home in English, Spanish, or Chinese.
Duarte, CaliforniaAges 65 years+ - NCT06027996Recruiting
Melodi Matrix in breast reconstruction
This trial tests a new mesh-like device called Melodi Matrix to support breast reconstruction after mastectomy. It may help women who are planning immediate two-stage implant reconstruction after removing one or both breasts.
Palo Alto, CaliforniaAges 22 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- City of Hope · 4 studies
- Kaiser Permanente-Oakland · 3 studies
- Kaiser Permanente Downey Medical Center · 2 studies
- Rady Children's Hospital · 2 studies
- Stanford University · 2 studies
- UCSF Benioff Children's Hospital Oakland · 2 studies
- University of California · 2 studies
- University of California, Los Angeles · 2 studies
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 342 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.