Clinical trials · California
Health clinical trials in California
We’re tracking 343 recruiting health studies with a site in California — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT05589714Recruiting
Study your rare eye gene and track retinal disease over time
This study builds a registry and tracks the natural history of rare retinal dystrophies while also testing people for disease-causing gene variants. It may help researchers better understand what causes retinal degeneration and how it progresses.
Los Angeles, CaliforniaAges 4 years+ - NCT05591118RecruitingPhase 3
Catheter treatment to remove blood clots in the lungs
This Phase 3 trial tests a catheter-based procedure to remove a lung blood clot (pulmonary embolism) and reduce strain on the heart. It may help people who have specific CT scan signs of right-heart strain.
San Diego, CaliforniaAges 18 years+ - NCT05608317Recruiting
Track healing of draining leg ulcers with a foam dressing
This study follows how a non-bordered foam dressing helps chronic leg ulcers that leak fluid (exuding). It mainly aims to see how the wound changes over time, and whether the dressing is comfortable and effective along with standard care.
San Francisco, CaliforniaAges 18 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Pomona, CaliforniaAges 18–79 - NCT05620719Recruiting
Study delayed headache after head injury in veterans
This study looks at treatment for ongoing headache that starts or gets worse after a mild or moderate head/neck injury in veterans or active-duty service members. It may help by testing an approach aimed at reducing headache burden and improving daily functioning.
Los Angeles, CaliforniaAges 18–70 - NCT05642858Recruiting
Learn heart health tips for people living with HIV
This study tests a text-message education program to help people living with HIV manage cardiovascular (heart and blood vessel) health. It may be helpful if you are 40 or older and can use a smartphone to receive messages.
San Francisco, CaliforniaAges 40 years+ - NCT05697328Recruiting
Testing barotrauma effects of hyperbaric oxygen
This study looks at problems caused by pressure changes during hyperbaric oxygen therapy (HBOT). It may help the team understand risks and how to keep treatment safer while you get HBOT.
Walnut Creek, CaliforniaAges 18 years+ - NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT05701358Recruiting
Guiding heart stent decisions to fully treat blocked arteries after a heart attack
This trial compares two ways doctors decide which additional blocked heart arteries to treat with stents soon after a heart attack. It may help patients avoid later heart problems by testing a “complete revascularization” strategy planned after the initial culprit artery was treated.
Los Angeles, CaliforniaAges 18 years+ - NCT05702645Recruiting
Down syndrome long-term study after leukemia treatment
This study follows children and young adults with Down syndrome who have survived acute leukemia (ALL or AML) to learn about their longer-term health after treatment ends. It may help families and doctors understand what health problems to watch for and how to provide better follow-up care.
Madera, CaliforniaAges 6–39 - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT05766670RecruitingPhase 3
Calcium and antibiotic placed inside tibia nail for open fractures
This Phase 3 study tests whether a calcium/antibiotic “depot” released from an intramedullary nail can lower infection risk in certain open tibia fractures. It may help by delivering antibiotics right at the fracture area while the nail fixes the bone.
Los Angeles, CaliforniaAges 18 years+ - NCT05789758Recruiting
Study of Spinraza in pregnancy for 5q spinal muscular atrophy
This study looks at how Spinraza (nusinersen) taken during or before pregnancy affects people with 5q spinal muscular atrophy (SMA) and the health of their babies. It mainly fits those who were pregnant and received Spinraza around the time of conception or during pregnancy.
Palo Alto, CaliforniaAges 18–54 - NCT05869682RecruitingPhase 2
Bright light therapy for fatigue and depression in prostate cancer
This Phase 2 study tests whether a “bright white light” intervention can reduce cancer-related fatigue and depression in people with advanced prostate cancer receiving hormone-based treatment. If it works, it could improve day-to-day well-being while you’re on standard cancer therapies.
Duarte, CaliforniaAges 60 years+ - NCT05873634Recruiting
Using health records and testing to study heart failure types
This study combines electronic health record data and detailed heart testing to better understand different heart failure types and what treatments may work best for each. It mainly enrolls people with known heart failure, and also some people without heart failure for comparison.
Sacramento, CaliforniaAges 30 years+ - NCT05876156Recruiting
VR physical therapy versus traditional physical therapy for young patients
This trial studies whether virtual reality (VR) physical therapy works as well as usual (traditional) physical therapy for improving recovery after cancer-related care. It may help by making therapy sessions more engaging while still aiming for physical function and comfort.
Palo Alto, CaliforniaAges 10–25 - NCT05880537Recruiting
Dialysis access graft registry using a processed donor artery
This study follows people with kidney failure who need dialysis access, when they receive an AV (artery-to-vein) access graft made from a processed donor artery. It’s meant to track safety and how well the new graft performs in real-world care.
Torrance, CaliforniaAges 18 years+ - NCT05916469Recruiting
Hormone treatment for heavy periods in teens and young adults
This trial studies how a progestin hormone—given as an IUD or tablets—can help reduce heavy menstrual bleeding in people with certain bleeding-related conditions. It may help you by testing whether the treatment works and is practical for your situation.
Palo Alto, CaliforniaAges 10–24 - NCT05924971RecruitingPhase 2
Taking aspirin to reduce complications after severe preeclampsia
This trial looks at whether aspirin after delivery can help postpartum recovery in people diagnosed with preeclampsia with severe features during the hospital stay. You might be considered if your care is through specific clinics at Long Beach Memorial.
Long Beach, CaliforniaAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Pasadena, CaliforniaAges 18 years+ - NCT05981573Recruiting
Measuring methadone doses for chronic pain
This trial is for people with chronic pain who take daily methadone. It aims to measure how much methadone is in your body to help doctors find the right dose.
Lemon Grove, CaliforniaAges 18–70 - NCT05986279Recruiting
MINDGAPS: A balance and mental health study for military members
This study tests a program called MINDGAPS to help Veterans and active-duty service members with their balance and mental health. If you are a military member who can stand on your own and have not had a recent head injury, you may be eligible.
San Diego, CaliforniaAges 18 years+ - NCT05996627RecruitingPhase 2
Belumosudil for early treatment of chronic graft-versus-host disease
This trial tests a pill called belumosudil to see if it can help people with chronic graft-versus-host disease (a common complication after a stem cell transplant where donor cells attack your body). It is for patients who have symptoms but are not yet on strong immune-suppressing drugs.
Duarte, CaliforniaAges 18 years+ - NCT06046651Recruiting
Blood sample collection for lab research
This study collects blood samples from healthy adults to help researchers learn more about how to run lab tests. It involves one visit or at-home collection and might help future medical research.
San Francisco, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- University of California, San Francisco · 4 studies
- City of Hope Comprehensive Cancer Center · 2 studies
- The Lundquist Institute at Harbor-UCLA Medical Center · 2 studies
- University of California, Davis Medical Center · 2 studies
- Adventist Health Glendale
- California Pacific Medical Center
- Cedars-Sinai Medical Center
- Center for Clinical Trials, Inc.
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 343 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.