Clinical trials · California
Health clinical trials in California
We’re tracking 341 recruiting health studies with a site in California — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT04404465Enrolling by invitation
Test blood/heart signals to understand atrial fibrillation changes
This study looks at early changes in the heart related to atrial fibrillation (AF) using health data and biomarkers. It aims to find better ways to predict or understand AF, especially around procedures like ablation or cardioversion.
San Francisco, CaliforniaAges 18 years+ - NCT06399861Recruiting
Humidity in incubators for tiny infants
This trial is testing different humidity levels in incubators for very premature babies (born before 25 weeks of pregnancy) to see which level works best. The goal is to improve care for these tiny infants in the neonatal intensive care unit (NICU).
San Diego, CaliforniaAges birth–1 day - NCT07125729Recruiting
Early cancer detection test for colorectal cancer
This trial uses two blood tests (Signatera and Haystack) to look for tiny bits of cancer DNA after surgery, to find out if the cancer comes back as early as possible. People with stage II, III, or IV colorectal cancer who have had or will have surgery to remove their tumor may join.
Corona, CaliforniaAges 18 years+ - NCT06581146Recruiting
Liver health study for boys with XLMTM
This study looks at how the liver works in boys with a serious muscle condition called XLMTM. It checks whether their liver is healthy, which may help doctors better understand the condition and guide future treatments.
Santa Monica, CaliforniaAges Up to 17 years - NCT07741968Recruiting
Online program to ease fear of cancer returning
This study tests an online program designed to help women with advanced or certain types of breast or gynecologic cancer manage their fear of the disease progressing or returning. The program aims to reduce anxiety and improve quality of life.
Arcadia, CaliforniaAges 18 years+ - NCT06808828Recruiting
Occupational therapy for survivors of partner violence
This trial tests if occupational therapy can help adults who have experienced intimate partner violence improve daily living skills and well-being. It is open to anyone 18 or older already getting help from a domestic violence organization.
Loma Linda, CaliforniaAges 18–70 - NCT03957928Recruiting
Mango pulp study for hunger and heart-health markers
This study tests whether eating fresh mango pulp can make you feel fuller (less hungry) and improve “heart-health” measurements. It may help people who are interested in diet changes, especially those with higher body weight and related health risks.
San Diego, CaliforniaAges 18–55 - NCT06476795Recruiting
Grape pomace from chardonnay for heart and gut health in postmenopausal women
This study tests if consuming a powder made from chardonnay grape pomace (the leftover skins and seeds from winemaking) can improve gut and heart health in postmenopausal women. You may be a good fit if you are between 45-70, have gone through menopause, and have higher levels of blood fats called triglycerides.
Davis, CaliforniaAges 45–70 - NCT06880055Recruiting
Shield blood test for colorectal cancer screening
This study is testing the Shield blood test for people at average risk of colorectal cancer. It looks at how well the test works for screening, so you can learn about your risk with a simple blood draw.
Anaheim, CaliforniaAges 45–81 - NCT04604418Recruiting
Tracking outcomes during non-heart procedures in children with heart defects
This study looks at how children with congenital heart disease do during routine non-heart procedures, including medical or minor treatments that are not heart-related. It also measures how much health care they use afterward, which may help improve care planning for families.
Los Angeles, CaliforniaAges Up to 21 years - NCT06233344RecruitingPhase 2
Mindfulness and psilocybin study for healthy adults
This study tests whether combining mindfulness training with a single dose of psilocybin (a psychedelic found in certain mushrooms) can help healthy adults. It aims to explore how these two approaches together might improve well-being.
Los Angeles, CaliforniaAges 25 years+ - NCT06508164Recruiting
International registry for rare RYR2 variants
This study creates a registry for people with rare changes in the RYR2 gene that affect heart function. Researchers will collect information to better understand these conditions and improve care.
San Francisco, CaliforniaAges Any age - NCT05958654Recruiting
Screening for risk of readmission during home care visits
This study tests a universal “screening” approach during home-based primary care visits to spot which patients may be at higher risk of problems that could require urgent care or hospital return. It may help patients and their care team catch risks earlier and adjust care sooner.
San Francisco, CaliforniaAges 18 years+ - NCT06027996Recruiting
Melodi Matrix in breast reconstruction
This trial tests a new mesh-like device called Melodi Matrix to support breast reconstruction after mastectomy. It may help women who are planning immediate two-stage implant reconstruction after removing one or both breasts.
Palo Alto, CaliforniaAges 22 years+ - NCT06022965Recruiting
Telemedicine support for older adults with cancer
This study uses telemedicine (video or phone visits) to help older adults with cancer, especially those in underserved communities, get better care. If you're 65 or older and starting a new cancer treatment, you may be able to join from home in English, Spanish, or Chinese.
Lancaster, CaliforniaAges 65 years+ - NCT05629013Recruiting
After-action reviews to improve child welfare teams’ care
This study asks child welfare teams and families to review what happened in their team planning meetings, to help improve how services get connected. It may help strengthen the way support services are identified and linked for children in ongoing child welfare cases.
San Diego, CaliforniaAges 6 years+ - NCT04712461Recruiting
Support program to reduce therapist burnout
This trial tests whether adding specific implementation supports can reduce burnout in therapists who provide evidence-based care for children who have experienced trauma. It may help therapists feel more supported while delivering these child trauma treatments.
San Diego, CaliforniaAges 3–99 - NCT05011149RecruitingPhase 3
Medicine for early treatment of a leaking heart vessel
This trial studies whether giving medicine soon can help preterm babies with a patent ductus arteriosus (a temporary leaking blood vessel in the heart). It aims to see if early treatment improves outcomes for very early gestational age infants.
San Diego, CaliforniaAges Up to 3 days - NCT04736667Recruiting
Screening survey for mitral valve treatment planning
This study is for people who did not pass an initial screening for a specific mitral valve procedure called TMVI. It may help the team understand screening results and improve how patients are assessed for the right next steps.
Los Angeles, CaliforniaAges 18 years+ - NCT03869814Recruiting
Blood test to study cancer signals without invasive procedures
This study looks at a non-invasive blood test to detect cancer-related “signal patterns” and see how well they match different types of cancer. It may help researchers learn better ways to find or understand cancer using less invasive testing.
San Diego, CaliforniaAges 21–80 - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT03085875Recruiting
Healthy Pregnancy Study for Moms Using Phone Apps
This study looks at healthy pregnancy habits and support for expecting moms (and moms up to 8 weeks after delivery) through a research community. It may help you compare or improve health behaviors with guidance and study activities delivered on your phone or tablet.
La Jolla, CaliforniaAges 16 years+ - NCT02825654Enrolling by invitation
Deployed Veterans Study of Service and Health
This study looks at how military service and deployment experiences relate to health and wellbeing in veterans who served after 9/11. It may help researchers understand which factors affect long-term health.
San Diego, CaliforniaAges Any age - NCT07437911Recruiting
Can a Supplement Help with Nutrient Gaps for GLP-1 Users?
This study tests whether a daily supplement can help fill nutrient gaps and improve gut health for people who are already taking GLP-1 weight-loss medications (like Ozempic or Wegovy). Participants must be on a stable dose for at least 8 weeks and be generally healthy without other chronic conditions.
Santa Monica, CaliforniaAges 18–59
Where these studies are running in California
Institutions with a site for the recruiting health studies listed above.
- City of Hope · 3 studies
- City of Hope Antelope Valley · 3 studies
- City of Hope Comprehensive Cancer Center · 3 studies
- City of Hope National Medical Center · 2 studies
- City of Hope Orange County Lennar Foundation Cancer Center · 2 studies
- San Diego State University · 2 studies
- Sharp Mary Birch Hospital for Women & Newborns · 2 studies
- Stanford University · 2 studies
What taking part in a health study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Common questions
- Are there health clinical trials in California?
- Yes. We're currently tracking 341 recruiting health studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a health study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a health trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New health studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.