Clinical trials · Pittsburgh, PA
Heart Diseases clinical trials in Pittsburgh
We’re tracking 16 recruiting heart diseases studies with a site in or near Pittsburgh — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Pittsburgh
- NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Pittsburgh, PennsylvaniaAges Any age - NCT06590467Recruiting
Abbott heart device registry study
This registry is a large, ongoing study that collects information about Abbott heart devices used in routine care. It helps doctors learn how well these devices work and how patients are doing over time, without changing your treatment plan.
Pittsburgh, PennsylvaniaAges Any age - NCT05918211RecruitingPhase 3
Udenafil test during exercise for teens with Fontan circulation
This trial tests whether udenafil helps teens and young people with Fontan circulation do better on exercise and breathing-related measures over time. You’d need to be on blood-thinning medicine, and be able to complete exercise testing safely.
Pittsburgh, PennsylvaniaAges 12–18 - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
Pittsburgh, PennsylvaniaAges 18–75 - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07525843Recruiting
Well-being education program for teens with heart disease
This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.
Pittsburgh, PennsylvaniaAges 12–17 - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06260059RecruitingPhase 4
Jardiance for adults with congenital heart disease and reduced heart function
This study tests a medicine called Jardiance (an SGLT2 inhibitor) to see if it helps improve heart function in adults with congenital heart disease who have recently experienced a drop in their heart pumping ability. Participants will take the medication alongside standard heart failure treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03217006Recruiting
Compare one vs multiple heart artery grafts for bypass
This study looks at whether using one artery graft or multiple artery grafts during heart bypass surgery works better for people with specific coronary artery disease. You may be randomized to one approach, and the trial team will follow outcomes after surgery.
Pittsburgh, PennsylvaniaAges 18–70 - NCT04073420Recruiting
Cardiac surgery registry to track Medtronic device outcomes
This registry collects real-world information from people who have had—or plan to have—an eligible Medtronic cardiac surgery device. It aims to better understand how these treatments do over time and help guide future care.
Pittsburgh, PennsylvaniaAges Any age - NCT04124120Recruiting
Single vs multiple bypass grafts for women heart surgery
This study compares outcomes of using one bypass graft versus multiple bypass grafts during coronary artery bypass surgery in women. It aims to see which approach leads to better recovery and heart outcomes for eligible patients.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Pittsburgh, PennsylvaniaAges Up to 1.3 years - NCT05472597Enrolling by invitation
Follow-up study about heart health after pregnancy
This study is continuing follow-up interviews and surveys to learn about heart health after pregnancy. If you already took part before, it may help researchers understand how postpartum health changes over time.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05933083Recruiting
In-person vs telehealth heart rehab comparison study
This study compares whether heart rehabilitation done in person or by telehealth (video/phone) works as well for people with certain heart conditions. It may help you and others choose the safest and most effective way to receive cardiac rehab.
Pittsburgh, PennsylvaniaAges 18 years+
Hear when a new Heart Diseases trial opens near Pittsburgh, PA
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Heart Diseases trials in other cities
Where these studies are running near Pittsburgh
Institutions with a site for the recruiting heart diseases studies listed above.
- University of Pittsburgh Medical Center · 5 studies
- UPMC Children's Hospital of Pittsburgh · 4 studies
- UPMC Presbyterian Hospital · 4 studies
- Allegheny General Hospital · 3 studies
- Allegheny Health Network · 2 studies
- Bryn Mawr Hospital
- Magee-Womens Hospital of UPMC
- Magee-Womens Research Institute
What taking part in a heart diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting heart diseases studies in Pennsylvania.
Common questions
- Are there heart diseases clinical trials near Pittsburgh?
- Yes. We're currently tracking 16 recruiting heart diseases studies with a site near Pittsburgh, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a heart diseases study near Pittsburgh?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pittsburgh to take part?
- Not necessarily. These studies have a site near Pittsburgh, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a heart diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New heart diseases studies open near Pittsburgh regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.