Clinical trials
Hepatic Cancer clinical trials
Below are recruiting hepatic cancer clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06641713Recruiting
Comparing two liver cancer treatments for large tumors
This trial compares two treatments for people with large liver tumors. One is a liver artery chemotherapy infusion and the other is a chemo-embolization procedure. The study will see which approach works better.
Beijing, Beijing MunicipalityAges 18–75 - NCT06898398Recruiting
TACE before surgery for large liver cancer
This trial combines a procedure called TACE (which blocks the blood supply to the tumor) with surgery to remove a large liver tumor. It is for people newly diagnosed with a large liver cancer that hasn't spread and can be completely removed with surgery.
Beijing, Beijing MunicipalityAges 18–75 - NCT06934018Recruiting
Surgical margin width for liver-only colorectal cancer spread
This trial tests whether a wider surgical margin (at least 7mm) during liver surgery improves survival and reduces cancer return in patients whose colorectal cancer has spread to the liver but not elsewhere. It aims to remove all visible liver tumors with a safe margin.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06658782Recruiting
MRI vs ultrasound for liver cancer detection in high-risk people
This trial compares two types of scans to see which detects liver cancer better in people at high risk. You would receive either an MRI with contrast or an ultrasound every 6 months to monitor for liver cancer.
Oxford, OxonAges 18 years+ - NCT05361551Recruiting
Test-guided liver ablation for up to five colorectal metastases
This study tests a planning and confirmation software tool during a needle-based liver procedure to treat colorectal cancer metastases. It aims to help doctors cover tumors more completely while reducing the chance of leaving tumor tissue behind.
Houston, TexasAges 18 years+ - NCT07445412Recruiting
Liver regeneration study for patients with small future liver remnant
This trial tests techniques to help the liver grow before surgery in people who have a liver tumor and whose future liver remnant is too small. The goal is to make the liver big enough to safely remove the tumor.
Bologna, BolognaAges 18 years+ - NCT05345847Recruiting
Steroid-sparing treatment for immune hepatitis during cancer immunotherapy
This trial studies a way to treat inflammation of the liver (hepatitis) caused by immune cancer medicines (anti-PD-1/PD-L1, sometimes with anti-CTLA-4) without relying on high-dose steroids. It may help reduce steroid side effects while keeping liver inflammation under control.
Calgary, AlbertaAges 18 years+ - NCT05286814RecruitingPhase 2
Pump-delivered therapy plus chemo for liver-metastatic cancers
This phase 2 study tests a liver-targeted medicine delivered through a special implanted pump, combined with standard chemo, for cancers that spread mainly to the liver. It may help control tumor growth in the liver and improve outcomes compared with standard treatment alone.
Bethesda, MarylandAges 18–120 - NCT07062055RecruitingPhase 2
A study of combination therapy for advanced liver cancer with spread
This trial tests a combination of immunotherapy (iparomlimab/tuvonralimab), a targeted drug (bevacizumab), and radiation (SBRT) plus liver-directed chemo (HAIC) for people with advanced liver cancer (HCC) that has spread to blood vessels or a few other places. It aims to see if this approach can help control the cancer.
Jinan, ShandongAges 18–70 - NCT06950814Recruiting
Impact of extra treatment after surgery for liver cancer
This study looks at whether additional treatment after liver surgery (like chemotherapy or radiation) can help people with a rare and aggressive liver cancer called primary hepatic sarcomatoid carcinoma (PHSC). It only includes people who had surgery and no other cancer treatments before that.
Chengdu, SichuanAges 18 years+ - NCT07276386RecruitingPhase 2
Combination therapy for metastatic uveal melanoma
This trial tests a two-part treatment for uveal melanoma that has spread to the liver. First, you get a liver-directed chemotherapy (melphalan) through a special procedure called PHP, then you receive an immunotherapy drug (tebentafusp) that helps your immune system attack the cancer.
Tampa, FloridaAges 18 years+ - NCT06681818Recruiting
New method to measure liver regrowth after surgery
This study tests a new way to measure how well your liver grows back and heals after part of it is removed. The goal is to predict and prevent complications after surgery.
Englewood, New JerseyAges 18 years+ - NCT04782557Recruiting
Ultrasound-guided blood sampling to track cancer DNA
This study uses an ultrasound-guided procedure to collect blood and check for cancer DNA (small bits of tumor material in the bloodstream). It aims to see whether this method can better track how gastric, pancreatic, or colorectal cancer responds to treatment.
Hong KongAges Any age - NCT05884723Recruiting
Ketogenic diet before liver surgery for fatty liver
This trial tests whether a ketogenic (very low-carb) diet before liver surgery can reduce fat in the liver. It is aimed at people with colorectal liver metastases who already have fatty liver seen on scans or biopsy.
London, OntarioAges 18 years+ - NCT03949231RecruitingPhase 3
Infusion immunotherapy through the liver artery for liver cancer
This trial tests a combination of immune “brakes” medicines (PD-1/PD-L1/CTLA-4) delivered through the liver’s artery, to help treat advanced liver cancer. It may help the immune system attack the cancer more effectively, especially if other local liver treatments aren’t possible or have stopped working.
Guanzhou, GuangdongAges 18–80 - NCT05726747Recruiting
Quality-of-life study for fluid buildup and muscle loss
This trial studies people with recurring fluid buildup in the belly (ascites) and looks at how treatments or supportive care affect quality of life and muscle strength. It may help researchers better understand which approaches improve day-to-day well-being when ascites keeps coming back.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06864481Recruiting
Study of liver inflammation from immunotherapy drugs
This study follows people who develop liver inflammation (hepatitis) after starting immunotherapy for cancer. It helps doctors understand how often this happens and how to manage it.
MontpellierAges 18 years+ - NCT06914648Recruiting
Liver preparation before surgery study for certain liver cancers
This study tests a procedure called portal vein embolization (PVE) to help grow the healthy part of the liver before surgery. It may be an option for people with certain liver cancers who need more healthy liver tissue before their operation.
New Haven, ConnecticutAges 18 years+ - NCT07717437Recruiting
Liver cancer registry for patients who had vein embolization
This registry collects medical images and health information from patients with liver cancer or liver metastases who had a procedure to block certain liver veins (PVE/HVE). The goal is to learn more about this technique and help future patients.
Chicago, IllinoisAges 18 years+ - NCT07764497RecruitingPhase 2
Chemotherapy through liver artery for colorectal cancer that spread to liver
This trial tests giving chemotherapy directly into the liver artery for people whose colorectal cancer has spread only to the liver and cannot be surgically removed. The goal is to shrink the tumors and make the liver healthy enough for surgery.
Toronto, OntarioAges 18 years+ - NCT07142122Recruiting
Comparing two types of stomach surgery for early upper gastric cancer
This trial compares two laparoscopic surgeries for early-stage stomach cancer in the upper part of the stomach. It looks at whether preserving a nerve (celiac branch of vagus nerve) during surgery leads to better recovery while still removing the cancer safely.
Fuzhou, FujianAges 18–75 - NCT05870969Recruiting
Digital monitoring to catch liver cancer risk early
This study tests a digital (computer/phone-based) system to help track people with higher risk of liver cancer so cancers can be found earlier. It may help by guiding regular check-ins and making early diagnosis more efficient.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06888063RecruitingPhase 2
Chemo pump into the liver for bile duct cancer that can be surgically removed
This trial tests whether giving extra chemotherapy directly to the liver through a small pump (called HAIP) before or after surgery can improve outcomes for patients with bile duct cancer inside the liver. It is for patients whose cancer is considered removable by surgery.
Rotterdam, South HollandAges 18 years+ - NCT02246634Recruiting
MRI screening to find liver metastases in bowel cancer
This study checks whether a special MRI scan (DW-MRI) can spot liver metastases early in people with high-risk colorectal cancer. Finding metastases sooner may help doctors choose the right treatment path.
Macclesfield, CheshireAges 16 years+
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Common questions
- Are there clinical trials for hepatic cancer?
- Yes. Clin2 currently lists 58 recruiting hepatic cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hepatic cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hepatic cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.