Clinical trials
Hepatitis clinical trials
Below are recruiting hepatitis clinical trials, each written for real people, not researchers. We’re tracking 484 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07006688RecruitingPhase 1
Ivosidenib for IDH1-mutated cancers with liver or kidney issues
This trial tests an oral drug (ivosidenib) for people with IDH1-mutated cancers who also have liver or kidney problems. It aims to find the right dose and see how safe and effective it is for these patients.
Atlanta, GeorgiaAges 18 years+ - NCT07023354RecruitingPhase 1
Study of BI 1291583 in people with and without liver problems
This trial tests how a new medicine, BI 1291583, enters the blood in people who have different levels of liver function (from normal to mild, moderate, or severe liver problems). It helps doctors understand if the dose needs to be adjusted for liver health.
Rialto, CaliforniaAges 18–80 - NCT07060638RecruitingPhase 2
Combination therapy for severe alcoholic hepatitis
This trial tests a combination of treatments for people with severe alcohol-related liver disease (alcoholic hepatitis) that has not responded to standard care. The goal is to improve liver function and help you stop drinking.
Indianapolis, IndianaAges 18–70 - NCT06559878Enrolling by invitation
Liver Mitochondria Study in Fatty Liver Disease
This study looks at how the liver's mitochondria (the energy powerhouses of cells) work in people with fatty liver disease. Participants will have an MRI scan and receive a small amount of fat solution through an IV to see how the liver processes fat.
Helsinki, UusimaaAges 18–75 - NCT05597488Recruiting
Measuring pressure to predict varice treatment response
This study checks whether a special ultrasound-guided measurement of blood pressure in your liver can help predict how well endoscopic treatment (banding varices or injecting bleeding sites) will work. It aims to improve outcomes by identifying who is more likely to respond.
Hong Kong, Hong KongAges 18–75 - NCT05403047RecruitingPhase 4
Preventing mom-to-baby hepatitis B with tenofovir
This study tests whether the medicine tenofovir disoproxil can help prevent passing hepatitis B from mother to baby during pregnancy. It is for pregnant women with an active hepatitis B infection who are early in their pregnancy (less than 24 weeks).
TokonbéréAges 16 years+ - NCT04476563Recruiting
Study liver injury from checkpoint cancer immunotherapy
This study looks at why some people develop liver inflammation after checkpoint inhibitor cancer treatment, called checkpoint inhibitor–induced liver injury (ChILI). It compares people with ChILI to similar cancer patients who are starting the same type of immunotherapy, to better understand and track these liver injury events.
NottinghamAges 18 years+ - NCT05583006Recruiting
Switch from entecavir to tenofovir for chronic hepatitis B
This trial studies switching people with chronic hepatitis B from entecavir (ETV) to tenofovir alafenamide (TAF). It may help if you feel your current entecavir treatment isn’t working well enough or is inconvenient.
Taichung, TaiwanAges 20 years+ - NCT03686137Recruiting
Liver surgery database study for liver tumors
This study collects information from people having liver surgery for a non-cancerous tumor or for liver cancer (primary or cancer that spread to the liver). It doesn’t usually add treatment—your care is documented to help doctors learn and improve future decisions.
Marseille, Bouches Du RhoneAges 18 years+ - NCT06742424RecruitingPhase 2
PD-L1 antibody + bevacizumab + liver chemo for advanced liver cancer
This trial tests whether combining a PD-L1 antibody (an immunotherapy) with bevacizumab (a drug that slows blood vessel growth to tumors) and a liver-directed chemotherapy infusion can help people with advanced liver cancer that has spread outside the liver. It is designed for patients who have not previously received these specific treatments.
Chengdu, SichuanAges 18–75 - NCT07340151Recruiting
Surgery for limited liver or lung pancreatic cancer spread
This trial tests whether removing or ablating limited liver or lung tumors from pancreatic cancer that has not spread elsewhere, along with a specific chemotherapy (NALIRIFOX), can help patients. It is for people who have not had any previous cancer treatment.
San Antonio, TexasAges Any age - NCT07117435RecruitingPhase 1
Targeted chemo into liver for colorectal cancer spread
This trial is testing a new way to give the chemotherapy drug paclitaxel directly into the liver (through a tiny tube) along with standard systemic treatment for people whose colorectal cancer has spread only to the liver and cannot be surgically removed. The goal is to see if this targeted approach works better than standard treatment alone.
Lishui, ZhejiangAges 18–75 - NCT06669806Recruiting
TIPS Stent Graft for Cirrhosis Complications
This study tests a TIPS stent graft (a tiny mesh tube placed in the liver to relieve pressure) for people with cirrhosis and complications like bleeding or fluid buildup. It aims to see how well it works and if it's safe.
Changsha, HunanAges 18–75 - NCT06988852RecruitingPhase 2
Chemo infusion into liver for colorectal cancer spread
This trial tests a strong chemotherapy combination given directly into the liver's blood supply (called HAIC) for people whose colorectal cancer has spread only to the liver and cannot be removed with surgery yet. The goal is to shrink the liver tumors enough so they can be surgically removed.
Wuhan, HubeiAges 18–75 - NCT07128108Recruiting
Testing a new ultrasound for liver fat and scarring
This study tests a new ultrasound technique called Visual Transient Elastography (ViTE) to measure fat and scarring in the liver. If you recently had a liver biopsy, this noninvasive test could help check your liver health without another needle procedure.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07450950Recruiting
Learning from patients before and after major cancer surgery
This trial looks at how people understand health information and what they expect before and after major cancer surgery. The goal is to help doctors better support patients by learning about their hopes and possible regrets.
Copenhagen, CopenhagenAges 18 years+ - NCT05830136Recruiting
Bicarbonate fluid during laparoscopic liver surgery
This trial tests whether giving a specific salt-water fluid (sodium bicarbonate in Ringer’s solution) during laparoscopic liver surgery can improve safety or outcomes. You may be eligible if you’re an adult planning this type of minimally invasive liver operation and can provide consent.
Nanjing, JiangsuAges 18 years+ - NCT04357600Enrolling by invitationPhase 1/Phase 2
Stem cell treatment for hepatitis B–related cirrhosis
This early-stage trial tests umbilical cord “mesenchymal” stem cells in people with liver scarring (cirrhosis) that is caused by hepatitis B. It may help improve liver function and related complications, but it is mainly designed to check safety and how well the treatment works.
Jakarta, DKI JakartaAges 18–65 - NCT07269301RecruitingPhase 1
Liver function and study drug processing
This study looks at how the medicine PF-07328948 is processed by people with different levels of liver function. It includes both healthy people and those with stable liver disease (classified as mild, moderate, or severe). The goal is to see if the liver condition affects how the drug works in the body.
Lake Forest, CaliforniaAges 18–74 - NCT06561529Recruiting
Stomach bypass stent for liver scarring in obese patients
This study tests a stomach bypass stent to treat liver scarring caused by fatty liver disease in people with obesity. If you have obesity and a confirmed liver condition called NASH with moderate scarring, this stent might help you achieve weight loss and improve your liver health.
Riga, RigaAges 18–65 - NCT06746701Recruiting
Peginterferon with NA to prevent liver cancer in hepatitis B
This study tests whether combining peginterferon alpha-2b with a nucleoside analog can lower liver cancer risk in people with chronic hepatitis B who have a family history of liver cancer. It compares the combination therapy to nucleoside analog alone.
Guangzhou, GuangdongAges 18–65 - NCT04942886Enrolling by invitation
Preventing hepatitis B reactivation after stem cell transplant
This trial tests whether taking the antiviral medicine entecavir before and after a stem cell transplant can prevent hepatitis B from “waking up” again. It may help protect your liver during a high-risk treatment period.
SeoulAges 19–70 - NCT06812390RecruitingPhase 2
Albumin plus diuretics for cirrhosis-related leg swelling
This study tests whether giving albumin (a protein) along with water pills helps reduce leg swelling in people with cirrhosis and ascites. It may be an option if your leg swelling hasn't improved with standard diuretics alone.
West Haven, ConnecticutAges 18 years+ - NCT06768216Recruiting
Mediterranean vs. low-fat diet for fatty liver in overweight kids
This trial compares two diets—a Mediterranean-style diet and a low-fat diet—to see which better reduces liver fat in overweight children and teens with fatty liver disease (MASLD). It aims to find a safe, effective eating plan for young people.
New Delhi, National Capital Territory of DelhiAges 8–18
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Common questions
- Are there clinical trials for hepatitis?
- Yes. Clin2 currently lists 484 recruiting hepatitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hepatitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hepatitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.