Clinical trials
HIV Treatment clinical trials
Below are recruiting hiv treatment clinical trials, each written for real people, not researchers. We’re tracking 85 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03449706Recruiting
Tracking immune changes in early HIV
This study looks closely at how your immune system and HIV infection markers change right after a new HIV diagnosis. It may help doctors understand the earliest stages of HIV and improve how infections are measured and followed over time.
Ghent, Oost-VlaanderenAges 18–65 - NCT05019495Recruiting
Study to improve quit-smoking support for people with HIV
This trial tests ways to deliver tobacco-quit treatment more effectively for people living with HIV. You may help researchers compare different quit-support approaches to see what works best.
Charleston, South CarolinaAges 21 years+ - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT03135886Recruiting
Testing for HIV in opioid treatment programs
This project studies how to improve offering and completing HIV (and hepatitis C) tests in opioid treatment programs. It may help increase timely follow-up and linkage to care when results are positive.
New York, New YorkAges 18 years+ - NCT05077527RecruitingPhase 1
CAR-T treatment for HIV and aggressive B-cell lymphoma
This trial studies a lab-made immune cell treatment (CAR-T) for adults who have HIV and aggressive B-cell non-Hodgkin lymphoma that has come back or did not respond to prior treatment. It aims to see if the treatment can control the lymphoma safely in this specific group.
Duarte, CaliforniaAges 18 years+ - NCT04663152Recruiting
Study support to help you stay on treatment
This study tests integrated support that includes counseling, help with following your treatment plan, and research activities to improve treatment adherence. You may be a good match if you live in Miami-Dade and meet the viral load requirement.
Miami, FloridaAges 18 years+ - NCT05835479RecruitingPhase 2
Rezafungin to treat Pneumocystis pneumonia in adults with HIV
This Phase 2 trial tests rezafungin, an antifungal medicine, to treat Pneumocystis pneumonia (PCP) in adults living with HIV. It may help people recover faster or more effectively from this serious lung infection.
Cape TownAges 18 years+ - NCT07031063RecruitingPhase 4
HIV treatment study for people starting therapy
This study compares two HIV medications (DTG/3TC and BIC/TAF/FTC) to see which works better and is safer for people who have never taken HIV treatment before. It may help you find a once-daily pill that controls the virus and has fewer side effects.
Mexico City, AzcapotzalcoAges 18 years+ - NCT06127290Recruiting
HIV treatment study for people in Eastern Europe and Russia
This study looks at how well newer HIV medicines work in people starting treatment for the first time in Eastern Europe and Russia. It also checks for drug resistance to find better treatment strategies.
CologneAges 18 years+ - NCT06267508Recruiting
HIV testing and treatment for newborns
This study looks at ways to test and treat newborns for HIV early to improve their long-term health. It is for mothers with HIV whose babies are less than 3 days old and who are willing to have their babies tested and followed at home.
BeiraAges 18 years+ - NCT06206564RecruitingPhase 2
Artesunate ointment for anal precancer in HIV-negative adults
This trial tests an artesunate ointment to treat high-grade anal precancer (HSIL) in people who do not have HIV. The goal is to see if the ointment can clear the abnormal cells caused by HPV.
Chicago, IllinoisAges 18 years+ - NCT06771843Recruiting
Helping men with HIV reduce drinking and improve HIV prevention
This study tests whether helping men with HIV who also drink heavily can lower their alcohol use and improve how well HIV treatment works to prevent passing the virus to others. It's for men living in fishing communities in Uganda.
KampalaAges 18 years+ - NCT07054931RecruitingPhase 2
Combination HIV vaccine and antibody therapy study
This trial tests a combination of an HIV vaccine and a new antibody treatment (GS-2872) to see if it can help control HIV without daily pills. It is for people with well-controlled HIV who are looking for ways to reduce their dependence on antiretroviral therapy.
LondonAges 18–64 - NCT07501624Enrolling by invitation
Pharmacist-led tobacco treatment for HIV patients
This study works with pharmacists at six Ryan White HIV clinics to help people with HIV quit smoking or using tobacco. If you have HIV, are 21 or older, and have already met with a pharmacist about tobacco, you may be able to join.
Charleston, South CarolinaAges 21 years+ - NCT07308886RecruitingPhase 2
CYT107 for Kaposi sarcoma in HIV patients with low CD4
This trial tests an experimental drug (CYT107) that boosts the immune system to help fight Kaposi sarcoma in people with HIV who have a low CD4 count despite good HIV treatment. It aims to see if the drug can improve KS tumors and quality of life.
Bethesda, MarylandAges 18–120 - NCT07569029RecruitingPhase 1
HIV vaccine with treatment break to boost immune response
This Phase 1 trial tests two new HIV vaccines (DV700P-RNA and DV701B1.1-RNA) combined with a monitored break from HIV medications in people with well-controlled HIV. The goal is to see if this approach safely strengthens the immune system's ability to fight HIV.
Birmingham, AlabamaAges 18–60 - NCT06880224Recruiting
HIV prevention and treatment for Nigerian youth aged 15-24
This study tests better ways to find and treat HIV in young people (ages 15-24) in Nigeria. It offers either HIV prevention medicine (PrEP) if you are HIV-negative, or HIV treatment if you are newly diagnosed with HIV.
Uyo, Akwa Ibom StateAges 15–24 - NCT06005298Recruiting
Testing SBIRT to help with PrEP and alcohol use
This study looks at whether talking about alcohol use can help people stick with their PrEP routine. It tests a simple program called SBIRT (Screening, Brief Intervention, and Referral to Treatment) to support your health and HIV prevention.
Louisville, KentuckyAges 18–85 - NCT05694637Enrolling by invitationPhase 4
Support to help daily smokers with HIV stay abstinent
This Phase 4 study tests a smoking-quit support approach (reinforcement and coaching) to help people with HIV stop smoking and stay smoke-free. It may help improve smoking abstinence while you continue HIV care.
Francistown, Central DistrictAges 18 years+ - NCT05373758Recruiting
Help for people whose HIV treatment is not working
This trial tests different ways to manage “virologic failure,” meaning HIV viral load stays high while taking TLD (a common HIV medicine combination). It may help people better control the virus and improve treatment results, especially in parts of sub-Saharan Africa.
DurbanAges 15 years+ - NCT06226155Recruiting
HIV prevention support for pregnant women in Zimbabwe
This study in Zimbabwe tests a program to help pregnant women start and stay on PrEP (medication that prevents HIV). It aims to make PrEP easier to use during pregnancy for women who are at risk of HIV.
HarareAges 15–55 - NCT06463886Recruiting
HIV medication support for Black women with trauma
This study explores ways to help Black women with HIV who have experienced trauma stick with their HIV medication. It looks at whether extra support can improve viral suppression and overall health.
Miami, FloridaAges 18 years+ - NCT07217379RecruitingPhase 1
HIV treatment interruption and new drugs study
This study tests two investigational drugs (MGD014 and MGD020) in people with HIV who have had their virus well controlled on standard treatment for at least 2 years. Some participants will temporarily stop their HIV medicines to see how the new drugs work.
Chapel Hill, North CarolinaAges 18–65 - NCT07711223RecruitingPhase 1/Phase 2
New HIV pill compared to standard treatment for untreated adults
This trial compares a new HIV medication (ACC017) to an existing one (dolutegravir) in adults who have HIV but have never taken HIV drugs before. The goal is to see if the new pill works as well and is safe.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for hiv treatment?
- Yes. Clin2 currently lists 85 recruiting hiv treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.