Clinical trials · Maryland
HIV clinical trials in Maryland
We’re tracking 55 recruiting hiv studies with a site in Maryland — including Phase 1 and Phase 1/Phase 2 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT05320835Recruiting
Talk-based overdose prevention for people using opioids
This trial tests an overdose prevention approach for people who have used opioids recently. It aims to help reduce the risk of overdose by offering a structured prevention intervention.
Baltimore, MarylandAges 18 years+ - NCT05163301Recruiting
Alcohol relapse prevention for adults living with HIV
This study looks at ways to help people with HIV reduce the chance of heavy drinking coming back after a period of lower-risk drinking. It will use regular patient-reported check-ins about alcohol use to understand relapse patterns and test the approach’s impact.
Baltimore, MarylandAges 18 years+ - NCT04941274RecruitingPhase 1/Phase 2
Abemaciclib for Kaposi sarcoma in people with or without HIV
This Phase 1/2 study tests the medicine abemaciclib to shrink Kaposi sarcoma (KS) lesions and control the disease. It includes both people with HIV and people without HIV, and may help when KS has not responded well to prior treatment or when certain KS stages are present.
Bethesda, MarylandAges 18–99 - NCT04142047Recruiting
Study muscle energy and fatigue in older adults
This study measures how older adults’ muscles use energy and how easily they tire during activity. It includes both people with HIV (with stable treatment and an undetectable viral load) and people without HIV to better understand differences in fatigue.
Baltimore, MarylandAges 60–90 - NCT01875588Recruiting
Long-term study of thinking and memory in adults with HIV
This study looks at how thinking and memory change over time in adults with HIV and compares them with adults without HIV. Researchers will do regular visits and brain/cognitive testing to understand what affects thinking and memory and to learn what might help.
Bethesda, MarylandAges 18–110 - NCT00767312Enrolling by invitation
Study how HIV multiplies during HIV drug treatment
This study looks at how HIV continues to multiply (or stays suppressed) while you are taking antiretroviral therapy, using blood samples. It may help researchers better understand what HIV is doing during treatment and why some people experience changes like viral rebound.
Bethesda, MarylandAges 18–99 - NCT00001316Recruiting
Study viral levels in blood and lymph node tissue with HIV
This study measures how much HIV is in your blood and lymph node tissue. If you qualify, you would also allow blood and other tests (including genetic and hepatitis screening), which may help researchers better understand how HIV affects the body.
Bethesda, MarylandAges 18–100 - NCT00029445Recruiting
Blood and Cell Collection Study for HIV Research
This research study collects blood cells from adults with HIV and their family members to understand why some people's immune systems control HIV better than others. Researchers will use your cells to study HIV immunity and develop better treatments.
Bethesda, MarylandAges 18–100 - NCT00789009Recruiting
Monitoring people with known or suspected HIV infection
This study tests how well researchers can track HIV-related health and immune changes over time by collecting blood and other samples. It may help you and your care team by creating detailed monitoring, even if your HIV diagnosis is new or still being evaluated.
Bethesda, MarylandAges 18 years+ - NCT00039689Recruiting
Blood collection study for newly diagnosed HIV research
This research study collects blood cells from people recently diagnosed with HIV who haven't started HIV medicines yet. Researchers use these samples to understand how HIV affects the immune system and develop better treatments.
Bethesda, MarylandAges 18–120 - NCT00006518Recruiting
Tissue samples from people with viral infections or cancer
This study collects tissue and blood samples from people who have or have been exposed to certain viruses (HIV, KSHV, HPV, EBV, or HTLV-1) or who have developed cancer or precancerous skin lesions. The samples help researchers understand how these viruses may lead to cancer.
Bethesda, MarylandAges 18–120 - NCT07438041Recruiting
Helping young people start prep for hiv prevention
This study helps young people who are at risk for HIV get on PrEP—a daily pill or shot that prevents HIV. It tests different ways to help you start and stay on PrEP, with care available at clinics or in your community.
Baltimore, MarylandAges 13–24 - NCT07778459Recruiting
Liver transplant study for people with HIV
This study tests whether it's safe and effective for people with HIV to receive a liver transplant from a donor who also has HIV. It aims to expand access to transplants for people with HIV.
Baltimore, MarylandAges 18 years+ - NCT07525544RecruitingPhase 1
Safety Study of VH4770359 in Healthy Adults
This is an early-stage safety study testing a new investigational drug (VH4770359) in healthy volunteers. Researchers want to understand how the body processes the drug and ensure it is safe and well-tolerated.
Baltimore, MarylandAges 18–55 - NCT07349758RecruitingPhase 1
Single dose of two PrEP tablets in healthy volunteers
This study tests how taking two tablets of a PrEP medication (F/TAF) at once affects healthy volunteers. It helps us understand the safety and how the body processes the drug.
Baltimore, MarylandAges 18 years+ - NCT07040319RecruitingPhase 1/Phase 2
Hepatitis C treatment study for pregnant women
This study tests a medicine called glecaprevir/pibrentasvir for pregnant women with hepatitis C, with or without HIV. It aims to see how the medicine works in the body and if it is safe during pregnancy.
Baltimore, MarylandAges 16–45 - NCT06908083Enrolling by invitationPhase 1
Stopping HIV treatment with antibody therapy
This trial tests whether a combination of powerful antibodies (bNAbs) can help control HIV after stopping standard HIV treatment. Participants will pause their daily HIV medications while receiving these antibodies, and doctors will closely monitor their immune system and virus levels. It's for people who are already well-controlled on HIV treatment and have participated in a specific earlier study.
Bethesda, MarylandAges 18–70 - NCT06585631Recruiting
Collaborative care for young men with HIV and substance use
This study looks at how to better support young men living with or at risk for HIV while also addressing substance use. You'll work with a care team that helps you stay healthy and connected to services.
Baltimore, MarylandAges 15–29 - NCT06375122Recruiting
A study of Kaposi sarcoma over time
This study follows people with Kaposi sarcoma to learn more about the disease and how it changes over time. It may help doctors better understand and treat KS in the future.
Bethesda, MarylandAges 18–120 - NCT05769023Enrolling by invitation
Pilot test targeting HIV prevention for people who inject drugs
This pilot program studies where HIV risk is highest and uses that information to decide how prevention efforts should be delivered. If you’ve used opioids recently and you inject drugs, you may be invited to participate to help reduce HIV risk.
Baltimore, MarylandAges 18 years+ - NCT05663502Recruiting
Donate blood and tissue samples for HIV-related cancer research
This study collects blood and tissue samples to help researchers learn more about cancers related to HIV/AIDS. You may be able to join if you’re 18+ and have HIV and a cancer diagnosis, or (if HIV-negative) a certain cancer that is closely linked to AIDS-related cancers.
Baltimore, MarylandAges 18 years+ - NCT05580458RecruitingPhase 1/Phase 2
Shingles vaccine study for adults with well-controlled HIV
This Phase 1/2 study tests how safe and how well a shingles (varicella zoster) vaccine works in adults living with HIV whose immune status is measured by CD4 count, plus a healthy comparison group. It may help researchers understand whether the vaccine can safely boost protection in people with HIV.
Bethesda, MarylandAges 18 years+ - NCT05470491RecruitingPhase 1/Phase 2
Haploidentical bone marrow transplant with GVHD prevention drugs
This trial tests a reduced-intensity bone marrow transplant from a related donor (haploidentical), using medicines to help prevent a serious complication called GVHD. It is for people with certain blood cancers and aims to improve outcomes by balancing transplant benefit with lower treatment intensity.
Bethesda, MarylandAges 12–120 - NCT05389423RecruitingPhase 1
Pomalidomide plus chemotherapy for HIV-related lymphoma
This Phase 1 study tests whether a combination of pomalidomide and a dose-adjusted chemotherapy plan (EPOCH), with or without rituximab, can treat certain aggressive B-cell lymphomas in people living with HIV. It aims to find a safe dosing approach and see how well the treatment works for specific lymphoma types or high risk of spread to the brain.
Bethesda, MarylandAges 18–120
HIV trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting hiv studies listed above.
- National Institutes of Health Clinical Center · 13 studies
- Johns Hopkins University · 5 studies
- GSK Investigational Site
- Johns Hopkins Center for Adolescent and Young Adult Health
- Johns Hopkins University (Site #: 71119)
- Johns Hopkins University Baltimore
- Lighthouse Studies at Peer Point
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
What taking part in a hiv study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
HIV trials in other states
Common questions
- Are there hiv clinical trials in Maryland?
- Yes. We're currently tracking 55 recruiting hiv studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a hiv study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New hiv studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.