Clinical trials
HIV clinical trials
Below are recruiting hiv clinical trials, each written for real people, not researchers. We’re tracking 583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05077527RecruitingPhase 1
CAR-T treatment for HIV and aggressive B-cell lymphoma
This trial studies a lab-made immune cell treatment (CAR-T) for adults who have HIV and aggressive B-cell non-Hodgkin lymphoma that has come back or did not respond to prior treatment. It aims to see if the treatment can control the lymphoma safely in this specific group.
Duarte, CaliforniaAges 18 years+ - NCT04160455Recruiting
Study of GALIG proteins in adults with HIV on or off treatment
This study looks at how “GALIG” gene products affect the body’s internal recycling process (called autophagy) in people living with HIV. It may help researchers understand differences between people on HIV treatment, starting treatment, or not currently taking it.
OrléansAges 18 years+ - NCT05019495Recruiting
Study to improve quit-smoking support for people with HIV
This trial tests ways to deliver tobacco-quit treatment more effectively for people living with HIV. You may help researchers compare different quit-support approaches to see what works best.
Charleston, South CarolinaAges 21 years+ - NCT04949464Recruiting
Smoking quit coaching plus lung scans for people with HIV
This study tests a behavior-change program to help people with HIV quit smoking, along with routine low-dose lung CT scans to find warning signs early. It’s a feasibility study, meaning the main goal is to see if the approach is practical and acceptable, and if people can follow through.
La Jolla, CaliforniaAges 45–80 - NCT04941274RecruitingPhase 1/Phase 2
Abemaciclib for Kaposi sarcoma in people with or without HIV
This Phase 1/2 study tests the medicine abemaciclib to shrink Kaposi sarcoma (KS) lesions and control the disease. It includes both people with HIV and people without HIV, and may help when KS has not responded well to prior treatment or when certain KS stages are present.
Bethesda, MarylandAges 18–99 - NCT04943861Recruiting
Study on HIV and food insecurity support
This study is looking at food insecurity in adults living with HIV. It may help improve understanding of the barriers to healthy living and guide better support for people affected by HIV.
Winston-Salem, North CarolinaAges 18 years+ - NCT04883255RecruitingEarly Phase 1
Study cannabis effects on brain function in adults with HIV
This early-phase study looks at how cannabis (and the body’s cannabinoid system) may affect thinking and brain-related measures in people with HIV. You may be asked to avoid cannabis and complete several brain and health assessments to see how these factors relate.
San Diego, CaliforniaAges 18–65 - NCT04810858Recruiting
Study how chronic marijuana affects brain inflammation in HIV
This study looks at whether ongoing marijuana use changes “brain inflammation” and brain cell injury in people living with HIV. It may help researchers understand potential risks or protective effects and how treatment and brain health interact.
Winston-Salem, North CarolinaAges 25–59 - NCT04375800RecruitingPhase 2
Doravirine for children with HIV infection and stable treatment
This Phase 2 study tests doravirine (a type of HIV medicine) in children with HIV who are about 4 weeks to under 12 years old and weigh under 45 kg. It aims to see whether this regimen can control the virus safely, and some children may continue into an extension if they benefit.
Aurora, ColoradoAges 4 weeks–11 years - NCT04174755Recruiting
Semaglutide for weight loss in adults with HIV
This trial studies whether semaglutide (a diabetes-type weight-loss injection) helps adults with HIV lose weight. It also checks that it’s safe for people whose HIV is well controlled on regular treatment.
Dublin, DublinAges 18 years+ - NCT04142047Recruiting
Study muscle energy and fatigue in older adults
This study measures how older adults’ muscles use energy and how easily they tire during activity. It includes both people with HIV (with stable treatment and an undetectable viral load) and people without HIV to better understand differences in fatigue.
Baltimore, MarylandAges 60–90 - NCT02898987Recruiting
Study quality of care for adults living with HIV
This trial looks at how care is being provided to adults with HIV who may be on treatment or not, and regardless of immune strength. It may help improve future care plans by identifying what works best in real-world settings.
BelfortAges 18 years+ - NCT02699736Enrolling by invitation
HIV and hepatitis C study in European adults
This study follows people living with HIV who also have hepatitis C antibodies, to better understand how HIV and hepatitis C affect health over time. You may be able to join if you meet the age and enrollment requirements, even if your hepatitis C virus level is currently undetectable.
Buenos AiresAges 16 years+ - NCT02437526Enrolling by invitation
Testing an HIV treatment pause to see if cure is possible
This study looks at whether some people with HIV can keep the virus controlled even if they temporarily stop HIV medicines (an “analytic treatment interruption”). If you qualify, it may help researchers learn what it would take for an HIV cure.
Rochester, MinnesotaAges 18 years+ - NCT01206920Recruiting
DC study following HIV prevention and care experiences over time
This study follows people who receive HIV care in Washington, DC and people using HIV prevention medicines (like PrEP) to understand health needs and outcomes over time. It may help improve how HIV care and prevention are delivered in local clinics.
Washington D.C., District of ColumbiaAges Any age - NCT02154035Recruiting
Measuring HIV reservoir in Ugandans with suppressed virus
This study in Uganda looks at the HIV 'reservoir' (where the virus hides in the body) in people whose HIV is already well-controlled with medications. It involves blood draws and genetic testing to learn more about the virus.
KalisizoAges 18–49 - NCT01875588Recruiting
Long-term study of thinking and memory in adults with HIV
This study looks at how thinking and memory change over time in adults with HIV and compares them with adults without HIV. Researchers will do regular visits and brain/cognitive testing to understand what affects thinking and memory and to learn what might help.
Bethesda, MarylandAges 18–110 - NCT01161199Recruiting
Leukapheresis study in people living with HIV
This trial uses a special blood-filtering procedure (leukapheresis) along with blood tests to better understand how HIV affects the body. It may help researchers learn more about HIV “pathogenesis,” which means what drives disease in different people.
San Francisco, CaliforniaAges 18 years+ - NCT01202305Recruiting
Lymph node biopsies to study HIV in different patients
This study uses a small tissue sample from an often-accessible lymph node to learn how HIV affects the body. It may help researchers understand why some people control HIV better than others.
San Francisco, CaliforniaAges 18–70 - NCT00796146Recruiting
Study people newly infected with HIV to learn early changes
This study enrolls adults with a very recent (“acute”) HIV infection to follow them over time and better understand what happens early after infection. Your participation may help researchers improve how acute HIV is detected and managed.
Bangkok, BangkokAges 18 years+ - NCT00029445Recruiting
Blood and Cell Collection Study for HIV Research
This research study collects blood cells from adults with HIV and their family members to understand why some people's immune systems control HIV better than others. Researchers will use your cells to study HIV immunity and develop better treatments.
Bethesda, MarylandAges 18–100 - NCT00789009Recruiting
Monitoring people with known or suspected HIV infection
This study tests how well researchers can track HIV-related health and immune changes over time by collecting blood and other samples. It may help you and your care team by creating detailed monitoring, even if your HIV diagnosis is new or still being evaluated.
Bethesda, MarylandAges 18 years+ - NCT00006518Recruiting
Tissue samples from people with viral infections or cancer
This study collects tissue and blood samples from people who have or have been exposed to certain viruses (HIV, KSHV, HPV, EBV, or HTLV-1) or who have developed cancer or precancerous skin lesions. The samples help researchers understand how these viruses may lead to cancer.
Bethesda, MarylandAges 18–120 - NCT00767312Enrolling by invitation
Study how HIV multiplies during HIV drug treatment
This study looks at how HIV continues to multiply (or stays suppressed) while you are taking antiretroviral therapy, using blood samples. It may help researchers better understand what HIV is doing during treatment and why some people experience changes like viral rebound.
Bethesda, MarylandAges 18–99
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Common questions
- Are there clinical trials for hiv?
- Yes. Clin2 currently lists 583 recruiting hiv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hiv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hiv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.