Clinical trials
Hormones clinical trials
Below are recruiting hormones clinical trials, each written for real people, not researchers. We’re tracking 417 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04894188Recruiting
Hormone plus radiation before prostate surgery for high-risk cancer
This trial studies giving hormone treatment and radiation before prostate surgery to treat high-risk, locally advanced prostate cancer. It aims to improve cancer control by shrinking or controlling the tumor before removing it.
Douliu City/Huwei Township, Yunlin CountyAges 20–75 - NCT04912648Recruiting
Study of metabolic risk and androgens in Irish women
This study looks at how hormones called androgens may relate to “metabolic risk” (things like blood sugar and weight-related health) over time. It mainly needs healthy adult women who can avoid certain medications during the weeks before starting.
DublinAges 18 years+ - NCT04929288Recruiting
Study how hormones affect alcohol risk in men and women
This study looks at how brain activity and hormone-related factors may help explain differences in alcohol risk between men and women. It may help researchers understand why alcohol use differs by sex and how risk develops.
Columbus, OhioAges 21–26 - NCT06970912RecruitingPhase 2
ctDNA-Guided Reduced Chemo in HR+/HER2- Breast Cancer
This study is testing whether using a ctDNA blood test can help doctors decide if patients with hormone receptor-positive, HER2-negative breast cancer can safely receive less intensive chemotherapy after surgery. The goal is to reduce side effects while still preventing the cancer from coming back.
Beijing, Beijing MunicipalityAges 18–75 - NCT07366112RecruitingPhase 2
CDK4/6 inhibitor plus hormone therapy before breast cancer surgery
This trial tests a combination of a CDK4/6 inhibitor (a type of targeted therapy) with hormone therapy given before surgery for early-stage breast cancer that is hormone receptor-positive and HER2-negative. It aims to see if this approach can shrink tumors and improve outcomes.
Beijing, Beijing MunicipalityAges 18–75 - NCT04944836RecruitingPhase 2
Testosterone supplement with rotator cuff repair
This study tests whether taking a sex hormone (testosterone) around the time of rotator cuff surgery improves healing after repair. It may help some men recover better, but it only fits people with specific tear features and health conditions.
Salt Lake City, UtahAges 40–80 - NCT05020860RecruitingPhase 2
Study how early breast cancer responds on imaging and under a microscope
This Phase 2 study looks at how well early breast cancer shrinks with treatment and how that matches with what doctors find after surgery under the microscope. The goal is to learn better ways to predict and assess treatment success.
Houston, TexasAges 18 years+ - NCT05115474RecruitingPhase 2
Screening brain MRI study for stage IV breast cancer
This trial checks whether taking screening brain MRI scans in people with stage IV breast cancer helps find brain involvement earlier. It may help guide treatment decisions for those who would otherwise only get brain imaging after symptoms start.
Clearwater, FloridaAges 18 years+ - NCT05169112RecruitingPhase 3
Hormone therapy to prevent prostate cancer coming back
This trial studies whether hormone therapy (also called ADT) after prostate surgery lowers the chance that prostate cancer will return. It targets people with very low PSA after surgery but with a higher predicted risk of recurrence.
Halifax, Nova ScotiaAges 18 years+ - NCT05247268RecruitingPhase 2
Hormone therapy to shrink early uterine cancer in young women
This trial tests whether combining two hormone medicines can treat early endometrial (uterine) cancer while helping preserve the uterus and future fertility. You may be eligible if your cancer is early and limited, with no spread seen on scans, and you can safely take these medicines.
ShanghaiAges 18–45 - NCT05316129RecruitingPhase 1
Trial of your own engineered T cells for ovarian cancer
This Phase 1 study tests whether giving your own immune cells—engineered to target the FSH receptor—can control recurrent ovarian-related cancers. It’s mainly looking at safety and early signs of activity for patients whose cancer has not responded well to standard platinum chemotherapy.
Tampa, FloridaAges 18 years+ - NCT05318755Recruiting
Gender-affirming hormone therapy study for adults starting care
This study looks at starting gender-affirming hormone therapy (GAHT) for transgender people who have never had these treatments before. It may help you learn whether this approach is safe and effective for your goals as you begin care.
Beijing, Beijing MunicipalityAges 18–40 - NCT05335317Recruiting
Low-intensity laser for vaginal thinning and irritation
This trial studies whether a low-intensity nanosecond laser can improve vaginal atrophy (vaginal thinning) and related symptoms. It may help reduce discomfort for people who fit the study conditions and can complete the required visits and procedures.
Nizhny NovgorodAges 40–75 - NCT05352178RecruitingPhase 3
Targeted treatment for few-spread prostate cancer spots
This Phase 3 trial tests whether treating only a small number of prostate cancer metastases can help people with “oligorecurrent” (limited repeat) prostate cancer. It may reduce cancer activity while avoiding broader whole-body treatment for some patients.
LeuvenAges 18 years+ - NCT05404061Recruiting
Study for people who don’t lose weight after bariatric surgery
This study looks at people who have had bariatric surgery but still struggle to lose weight (or lose it poorly). It aims to better understand how to help “poor responders” and what might be interfering with weight-loss results.
LondonAges 18–70 - NCT05448547RecruitingPhase 3
Tested curative vs conservative treatment for older men with high-risk prostate cancer
This Phase 3 study compares an immediate curative treatment plan versus a more conservative approach in men age 75 and older with newly diagnosed, high-risk prostate cancer. The goal is to see which strategy controls the cancer while better protecting quality of life.
CopenhagenAges 75 years+ - NCT05452213RecruitingPhase 4
Study patterns of ribociclib response and resistance in breast cancer
This trial looks at how well ribociclib works and why it may stop working over time in people with advanced, hormone-receptor–positive, HER2-negative breast cancer. It also analyzes blood and tissue samples to help researchers understand resistance patterns and improve future treatment decisions.
Erlangen, BavariaAges 18 years+ - NCT05470504RecruitingPhase 2
Pegvisomant for severe insulin resistance from rare fat or gene problems
This Phase 2 study tests pegvisomant, a medicine that blocks growth hormone, to see if it can improve severe insulin resistance in people with a specific genetic cause or a rare fat distribution condition. If you fit the rare diagnosis, the study may help clarify whether growth-hormone blocking can improve blood sugar and related health markers.
Bethesda, MarylandAges 18–70 - NCT05479448Recruiting
Tracking what predicts response in new PMR or GCA
This study looks at people newly diagnosed with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) and uses their health and treatment information to learn what predicts how well treatment works. It may help your care in the future by improving which patients respond best and how.
BaselAges 18 years+ - NCT05524584RecruitingPhase 2
Anastrozole, fulvestrant, and abemaciclib for hormone-positive breast cancer
This trial tests whether combining three medicines can better control hormone-receptor–positive, HER2-negative metastatic breast cancer that cannot be cured with surgery or radiation. It may help shrink tumors and slow disease growth compared with standard hormone therapy approaches.
Orange, CaliforniaAges 18 years+ - NCT05526144RecruitingPhase 2
Thyroid hormone treatment for fatty liver in Veterans
This trial tests whether thyroid hormone can improve nonalcoholic steatohepatitis (fatty liver with inflammation) in Veterans. You may be asked to have a medically needed liver biopsy, and the study also focuses on safety in people with related conditions like diabetes and heart risks.
Columbia, MissouriAges 18–75 - NCT05567198Recruiting
Testing hormone shots to protect ovaries during lupus chemotherapy
This study looks at whether a monthly/3-month hormone medicine (a “GnRH shot”) can help protect ovaries in people with lupus who are treated with cyclophosphamide. It also compares this to lupus patients who do not receive the ovarian-protecting shot, using questionnaires to track outcomes.
Bethesda, MarylandAges 18–120 - NCT05578053Recruiting
Dalpiciclib for hormone receptor–positive advanced breast cancer
This trial studies whether dalpiciclib can slow down or control advanced hormone receptor–positive breast cancer and assess how safe it is. It’s for people whose cancer has come back in a limited way or spread and can’t be fully cured with surgery or radiation.
Shijiazhuang, HebeiAges 18 years+ - NCT05579366RecruitingPhase 1/Phase 2
Study drug for advanced ovarian and other solid cancers
This Phase 1/2 trial studies Rinatabart Sesutecan to treat advanced cancers, with special focus on certain ovarian cancer types. It’s meant for people whose cancer has come back or has not responded to prior treatments.
Phoenix, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for hormones?
- Yes. Clin2 currently lists 417 recruiting hormones studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hormones trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hormones trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.