Clinical trials
HPV clinical trials
Below are recruiting hpv clinical trials, each written for real people, not researchers. We’re tracking 251 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05582122RecruitingPhase 2
Tracking HPV16 DNA in blood to spot cancer coming back
This study checks whether a blood test for HPV16 DNA can predict when HPV-related throat cancer comes back after treatment. It may help improve follow-up care by catching recurrence earlier.
Saint-Denis, La RéunionAges 18 years+ - NCT03396718Recruiting
De-escalating radiation after HPV head and neck cancer surgery
This study looks at whether some people with HPV-positive throat/oropharynx cancer can safely receive a less intense form of radiation (and sometimes chemo) after surgery. It aims to reduce treatment burden while keeping the cancer under control, based on how high-risk the pathology looks.
Tübingen, Baden-WurttembergAges 18 years+ - NCT06358469Recruiting
Vulvar cancer surgery guided by HPV and p53 testing
This trial is for people with early-stage vulvar cancer that can be surgically removed. It looks at the cancer's HPV and p53 status to decide how much tissue to remove, aiming to reduce side effects while keeping the cancer away.
Kelowna, British ColumbiaAges 18 years+ - NCT05606133Recruiting
Test HPV DNA from blood to track cervical cancer risk
This study looks at a blood test that measures HPV DNA to help screen and monitor people with HPV-related cervical problems. If you have confirmed high-grade cervical changes or cervical cancer, the test may help doctors follow how your condition changes over time.
New York, New YorkAges 18 years+ - NCT06309225Recruiting
Adjusted Chemoradiation for HPV Throat Cancer in Older Adults
This trial tests adjusting the dose of chemotherapy and radiation for older adults (65+) with HPV-related throat cancer. The goal is to find a treatment that is effective but gentler on the body.
Jacksonville, FloridaAges 65–99 - NCT06254846Recruiting
Urine test for HPV cervical cancer screening
This study tests if a urine sample can replace a cervical swab for HPV testing during cervical cancer screening. If it works, it could make screening easier and less uncomfortable.
Saint-EtienneAges 30–65 - NCT06210854RecruitingPhase 2
HPV16/18 Vaccine Trial for Cervical Lesions
This trial tests a new vaccine (pBI-11) given with a device that uses mild electric pulses to help the vaccine enter cells. It is for people who have HPV16 or 18 but no high-grade cervical changes.
Birmingham, AlabamaAges 18 years+ - NCT06147388Recruiting
Can cervical precancer heal on its own?
This study watches to see if early precancerous cells (CIN 2 or 3) on the cervix can go away without treatment, especially in women under 40. It helps doctors understand who might avoid surgery.
PragueAges 18–40 - NCT06109870Recruiting
Increasing cervical cancer screening in Texas communities
This study tests a new community-based program to help women who are overdue for cervical cancer screening get easier access to testing. It’s designed for women in underserved areas of Texas who haven’t had a recent Pap or HPV test.
Austin, TexasAges 18 years+ - NCT06064877RecruitingPhase 3
Study of ficlatuzumab plus cetuximab for advanced head and neck cancer
This trial tests a combination of two drugs, ficlatuzumab and cetuximab, for people with recurrent or metastatic head and neck cancer that is HPV-negative and has not responded to prior immunotherapy and chemotherapy. It aims to see if this combination can help shrink tumors or slow the disease.
Gilbert, ArizonaAges 18 years+ - NCT06042543Recruiting
Cervical cancer screening trial for unscreened women
This trial tests a new, affordable way to screen for cervical cancer that can be done in low- and middle-income countries. It uses artificial intelligence to help decide who needs follow-up care.
Cincinnati, OhioAges 25–49 - NCT06016920RecruitingPhase 1/Phase 2
Study of VB10 with pembrolizumab for advanced head and neck cancer
This trial is testing a combination of two investigational drugs (VB10 and pembrolizumab) in patients with a specific type of head and neck cancer that has returned or spread. The goal is to see if this treatment is safe and effective.
MontpellierAges 18 years+ - NCT05985681RecruitingPhase 1
Vaccine to prevent HPV-related cancers
This trial tests a new vaccine called RG1-VLP that may help prevent cancers caused by HPV. It is for healthy women who have not had an HPV vaccine before and are willing to follow study procedures.
Madison, WisconsinAges 18–60 - NCT05984849Recruiting
A Game to Learn About the HPV Vaccine
This study uses a game to teach children ages 11-14 about the HPV vaccine and why it's important. It's for kids who haven't gotten the vaccine yet and their parent or guardian.
Chandler, ArizonaAges 11–14 - NCT05996016Recruiting
Gut and vaginal bacteria in HIV-positive women
This study looks at the types of bacteria living in the gut and vagina of women with HIV, including pregnant women. It aims to understand how these bacteria might affect health.
Beijing, Beijing MunicipalityAges 14 years+ - NCT05962242RecruitingPhase 2
HPV-tested de-escalated radiation for HPV-related throat cancer
This Phase 2 study uses HPV test results from your tumor to safely lower (de-intensify) the strength of radiation for some HPV-positive oropharyngeal throat cancers. It aims to reduce side effects while keeping cancer control effective.
Miami, FloridaAges 18 years+ - NCT05848557Recruiting
Mobile app study for cervical cancer screening and education
This study tests a mobile health tool (an app) and related surveys to improve knowledge and screening awareness for cervical cancer, including HPV risk and acceptability. It involves people working in cervical cancer screening and women in specific communities, with participation based on consent and eligibility for screening.
Kisumu, Kisumu CountyAges 18 years+ - NCT05799144RecruitingPhase 2
Pembrolizumab plus investigational HPV drugs for throat cancer
This Phase 2 trial studies pembrolizumab (an immune therapy) combined with investigational treatment(s) pBI-11 and TA-HPV for advanced or recurrent oropharyngeal cancer that is HPV-positive and has certain immune marker levels (PD-L1 CPS ≥ 1). It may help your immune system better attack cancer.
Birmingham, AlabamaAges 18 years+ - NCT05600842Recruiting
Lower-dose radiation for HPV-positive throat cancer
This trial tests whether using a de-escalated (lower/intensity-reduced) radiation approach can treat HPV-positive oropharyngeal squamous cell carcinoma. It may help reduce side effects while still keeping the cancer under control.
Orange, CaliforniaAges 18 years+ - NCT05576831Recruiting
Testing HPV and p53 to guide vulvar cancer surgery
This study looks at two tumor test results—HPV and p53—to help doctors decide how much tissue to remove during surgery for vulvar squamous cell carcinoma. It’s meant to reduce the risk of the cancer coming back while avoiding unnecessary removal when margins are only close.
Vancouver, British ColumbiaAges 18 years+ - NCT05539638Recruiting
Testing blood DNA for head and neck squamous cancer
This study looks at how tumor DNA found in a blood sample (a “DNA signal”) relates to head and neck cancer in the oropharynx. It may help doctors understand disease status and improve how they monitor treatment, for both HPV-positive and HPV-negative cancers.
Dundee, DD2 1SGAges 18 years+ - NCT05528237Enrolling by invitation
HPV self-test to help cervical cancer screening access
This trial studies whether letting people collect their own HPV test sample (a private, at-home option) makes cervical cancer screening easier for people with HIV and/or those who are often underserved. If you’ve declined a Pap test or it’s been 6+ months since your last screening, this may offer a more convenient way to check for HPV and cervical cancer risk.
Seattle, WashingtonAges 25 years+ - NCT05524480Enrolling by invitation
Help Latina women get overdue breast, cervical care
This trial tests an implementation program that helps clinics better provide breast and cervical cancer screening and HPV vaccination to Latina women who are behind on recommended care. It may help you catch up on screening or start HPV vaccination and connect you to low-cost services.
Houston, TexasAges 18–74 - NCT05390567Recruiting
Mobile reminders to help women catch up on cancer screening
This study tests a mobile outreach effort to help women who are behind on recommended cervical cancer screening. It may help you learn when to get screened and connect you to care that may be easier to access.
Gainesville, FloridaAges 25–65
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Common questions
- Are there clinical trials for hpv?
- Yes. Clin2 currently lists 251 recruiting hpv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hpv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hpv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.