Clinical trials
HPV clinical trials
Below are recruiting hpv clinical trials, each written for real people, not researchers. We’re tracking 251 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07029152Recruiting
Anal cancer screening for gay and bisexual men on PrEP
This study is screening gay and bisexual men for anal cancer by taking a swab sample. It aims to find early signs of cancer so it can be treated early.
BrugesAges 35 years+ - NCT06997068RecruitingPhase 2
Drug combination for returning head and neck cancer
This trial tests a combination of three drugs—methotrexate, erlotinib, and celecoxib—for people whose head and neck cancer has come back or spread. It is designed for patients in the rural Midwest who have already had or chosen not to have standard first treatment.
Rochester, MinnesotaAges 18 years+ - NCT06984861RecruitingPhase 2
Reduced radiation with chemo for HPV-related throat cancer
This trial tests if giving less radiation along with chemotherapy is safe and effective for people with HPV-positive throat cancer. It aims to reduce side effects while still controlling the cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT06005324RecruitingPhase 1
Personalized treatment for advanced head and neck cancer
This trial tests a custom treatment plan for people with advanced head and neck cancer that is not caused by HPV. It combines radiation and chemotherapy with a targeted drug called cetuximab, adjusted based on your tumor's characteristics.
Chicago, IllinoisAges 18 years+ - NCT06943547Enrolling by invitation
Study to improve cervical cancer screening in Puerto Rico
This trial tests how well certain programs can increase cervical cancer screening among women in Puerto Rico. If you are overdue for a Pap or HPV test, this study may help you get screened.
San Juan, PRAges 25–65 - NCT06949800RecruitingPhase 2
Probiotics to treat anal precancer (PROTECT trial)
This study tests if a probiotic called EXE-346 can help clear anal high-grade squamous intraepithelial lesions (HSIL), a precancerous condition, in people with HIV who are on effective antiretroviral therapy. If you have anal HSIL that wasn't fully removed by biopsy, you may be able to join.
San Francisco, CaliforniaAges 21 years+ - NCT06935188RecruitingPhase 2
Dalpiciclib plus cetuximab for certain head and neck cancers
This trial tests a new combination of two drugs (dalpiciclib and cetuximab) versus cetuximab alone for people with head and neck cancer that is HPV-negative, has not responded to prior immunotherapy, and is not curable with surgery. The goal is to see if the combination works better.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06868433RecruitingPhase 1
TMV vaccine alone or with pembrolizumab for advanced HNSCC
This trial tests a vaccine made from your own tumor to help your immune system fight head and neck cancer that has returned or spread. It is given alone or with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors or slow progression.
Atlanta, GeorgiaAges 18 years+ - NCT06825689Recruiting
Unidos Contra el VPH
This trial aims to increase cervical cancer screening and HPV vaccination among eligible individuals in Texas. It tests a text messaging intervention to help people who haven't had a Pap test in at least three years get screened.
El Paso, TexasAges 30–65 - NCT06808776Recruiting
Stories to prevent HPV cancers
This trial tests if sharing stories can help parents decide to get their child the HPV vaccine. It is for parents of children ages 9 to 12 who have not yet started the HPV shot series.
Hershey, PennsylvaniaAges 18 years+ - NCT06810739Recruiting
Women's Screening and Self-Testing Program (PROMETA)
This study tests a self-screening program for cervical cancer among women who are already receiving HIV care. It aims to make screening easier and more accessible.
MaputoAges 25–49 - NCT06751030Recruiting
Cervical cancer screening study for HIV-positive women in Nigeria
This study offers home-based education and cervical cancer screening using a simple vaginal self-collection method. It aims to increase access to care for women living with HIV in Nigeria.
AbujaAges 25–50 - NCT06702033RecruitingPhase 2
Surgery for HPV-related oropharyngeal cancer
This trial is testing a surgical approach for people with HPV-related oropharyngeal cancer that is stage I or II (but not the very smallest). The goal is to see if removing the tumor through the mouth and taking out neck lymph nodes is effective and safe. It may be an option if you are healthy enough for surgery.
St Louis, MissouriAges 18 years+ - NCT06670495Recruiting
HPV types and anal cancer in China
This study looks at how different types of HPV are linked to anal cancer in China. By testing your tumor sample, the researchers hope to better understand what causes anal cancer, which could help guide prevention and treatment.
ShanghaiAges Any age - NCT06662058Recruiting
Remote hearing test for head and neck cancer patients on cisplatin or radiation
This study tests a remote hearing test to monitor hearing changes in patients with head and neck cancer getting cisplatin chemotherapy and/or radiation. The goal is to catch hearing loss early so treatment can be adjusted.
Atlanta, GeorgiaAges 18 years+ - NCT06658405RecruitingPhase 2
HPV vaccine after cervical lesion treatment
This trial tests whether an HPV vaccine (Gardasil 9) can help women over 45 who still have HPV after treatment for a high-grade cervical lesion. It compares vaccinated and unvaccinated patients to see if vaccination lowers the risk of the lesion coming back.
LilleAges 45 years+ - NCT06636734RecruitingPhase 2
Lovastatin plus pembrolizumab for advanced head and neck cancer
This trial tests whether adding lovastatin (a cholesterol-lowering drug) to pembrolizumab (an immunotherapy) works better than pembrolizumab alone for head and neck cancer that has come back or spread. It's for people who haven't had immunotherapy before and aren't already on a statin.
Atlanta, GeorgiaAges 18 years+ - NCT06628570Recruiting
Screening methods for anal cancer in high-risk adults
This study is looking at ways to screen for anal cancer in people who are at higher risk, such as those with weakened immune systems or a history of abnormal cells in the lower genital tract. It aims to find better methods for early detection.
Miami, FloridaAges 30–80 - NCT06554158Recruiting
Lowering radiation for low-risk HPV throat cancer patients
This trial tests whether giving less radiation after surgery is safe and effective for people with early-stage HPV-related throat cancer. It aims to reduce side effects while still controlling the cancer.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06535139Recruiting
HPV Vaccine Study for Rural Kids 8 to 12
This study aims to help prevent HPV-related cancers by increasing HPV vaccination rates in rural areas. It is for parents of 8- to 12-year-olds who have not yet completed the two-dose HPV vaccine series.
Gainesville, FloridaAges 8–99 - NCT06513494Recruiting
Health education to boost HPV vaccine in youth
This trial tests whether active health education in schools can increase HPV vaccine coverage among students. It may help protect young people from HPV-related cancers.
Crato, CearáAges 9–14 - NCT06448026RecruitingPhase 2
Cemiplimab and cetuximab before surgery for mouth or throat cancer
This trial tests whether combining two targeted drugs (cemiplimab and cetuximab) before surgery can help people with recurrent mouth or throat cancer that has come back after initial treatment. It aims to see if this approach makes surgery more effective.
Houston, TexasAges 18 years+ - NCT06445114RecruitingPhase 2
Blood-Guided Chemoradiation for HPV-Positive Throat Cancer
This study tests whether a blood test that looks for circulating HPV DNA (ctDNA) can help doctors decide if you need chemotherapy after surgery for HPV-positive throat cancer. After you have surgery to remove the cancer, you receive radiation (possibly with chemotherapy) — the results of the blood test guide whether or not to add chemo.
Beverly Hills, CaliforniaAges 18 years+ - NCT06458062Recruiting
Pocket colposcopy for women with positive HPV test
This study tests a new, smaller device called a pocket colposcope to look at the cervix (the opening of the womb) in women who have had a positive HPV test. The goal is to see if this simpler tool can help find cell changes that might lead to cancer, so you can get treatment sooner.
NairobiAges 25 years+
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Common questions
- Are there clinical trials for hpv?
- Yes. Clin2 currently lists 251 recruiting hpv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hpv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hpv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.