Clinical trials
HPV clinical trials
Below are recruiting hpv clinical trials, each written for real people, not researchers. We’re tracking 259 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05625633RecruitingPhase 2/Phase 3
HPV vaccine vs placebo for stubborn skin warts
This study tests whether an HPV vaccine can help shrink or clear cutaneous (skin) warts that have not responded to prior treatments. Participants get the study vaccine or a placebo to compare results and safety.
Salt Lake City, UtahAges 18 years+ - NCT05640700Recruiting
Study of vaginal microbiome in HPV-related early cell changes
This study looks at the vaginal “microbiome” (the normal germs and bacteria in the vagina) in people who have had abnormal Pap smear or colposcopy results related to HPV. It may help doctors understand what to monitor and how to better identify early, pre-cancer changes in the cervix.
JerusalemAges 25–70 - NCT05727228Recruiting
Risk screening for HPV after LEEP
This study looks at how to sort people into higher- or lower-risk groups after abnormal HPV testing treatment (LEEP), using repeat HPV and Pap (cytology) tests. It may help improve follow-up plans by identifying who needs closer monitoring after LEEP.
Randers, Central JutlandAges 23–64 - NCT05848557Recruiting
Mobile app study for cervical cancer screening and education
This study tests a mobile health tool (an app) and related surveys to improve knowledge and screening awareness for cervical cancer, including HPV risk and acceptability. It involves people working in cervical cancer screening and women in specific communities, with participation based on consent and eligibility for screening.
KisumuAges 18 years+ - NCT05962242RecruitingPhase 2
HPV-tested de-escalated radiation for HPV-related throat cancer
This Phase 2 study uses HPV test results from your tumor to safely lower (de-intensify) the strength of radiation for some HPV-positive oropharyngeal throat cancers. It aims to reduce side effects while keeping cancer control effective.
Miami, FloridaAges 18 years+ - NCT05984849Recruiting
A Game to Learn About the HPV Vaccine
This study uses a game to teach children ages 11-14 about the HPV vaccine and why it's important. It's for kids who haven't gotten the vaccine yet and their parent or guardian.
Chandler, ArizonaAges 11–14 - NCT05996016Recruiting
Gut and vaginal bacteria in HIV-positive women
This study looks at the types of bacteria living in the gut and vagina of women with HIV, including pregnant women. It aims to understand how these bacteria might affect health.
Beijing, Beijing MunicipalityAges 14 years+ - NCT06016920RecruitingPhase 1/Phase 2
HPV16 vaccine plus Keytruda for oropharyngeal cancer
This trial tests a new vaccine (VB10.16) combined with the immunotherapy Keytruda (pembrolizumab) for people with HPV16-positive oropharyngeal cancer that has spread or come back. The goal is to see if the combination helps shrink tumors or slow cancer growth.
OlomoucAges 18 years+ - NCT06042543Recruiting
Cervical cancer screening trial for unscreened women
This trial tests a new, affordable way to screen for cervical cancer that can be done in low- and middle-income countries. It uses artificial intelligence to help decide who needs follow-up care.
Cincinnati, OhioAges 25–49 - NCT06064877RecruitingPhase 3
Study of ficlatuzumab plus cetuximab for advanced head and neck cancer
This trial tests a combination of two drugs, ficlatuzumab and cetuximab, for people with recurrent or metastatic head and neck cancer that is HPV-negative and has not responded to prior immunotherapy and chemotherapy. It aims to see if this combination can help shrink tumors or slow the disease.
Gilbert, ArizonaAges 18 years+ - NCT06082765Recruiting
Cervical cancer screening with menstrual blood test
This trial tests if a new DNA test (NGS-HPV) using menstrual blood can detect HPV and help screen for cervical cancer. You may participate if you have regular periods and plan to get cervical screening.
Wuhan, HubeiAges 20–60 - NCT06223568RecruitingPhase 2
Chemo with or without a vaccine for HPV-related throat cancer
This trial tests whether adding an immunotherapy vaccine (PRGN-2009) to standard chemotherapy before surgery works better than chemotherapy alone for people with newly diagnosed HPV-positive oropharyngeal (head and neck) cancer.
Bethesda, MarylandAges 18–120 - NCT06254846Recruiting
Urine test for HPV cervical cancer screening
This study tests if a urine sample can replace a cervical swab for HPV testing during cervical cancer screening. If it works, it could make screening easier and less uncomfortable.
Saint-EtienneAges 30–65 - NCT06309225Recruiting
Adjusted Chemoradiation for HPV Throat Cancer in Older Adults
This trial tests adjusting the dose of chemotherapy and radiation for older adults (65+) with HPV-related throat cancer. The goal is to find a treatment that is effective but gentler on the body.
Jacksonville, FloridaAges 65–99 - NCT06326294Recruiting
Comparing two treatments to reduce cervical cancer risk in women with HIV
This study compares two treatments (Thermal Ablation and LEEP) to lower the risk of cervical cancer in women living with HIV. It aims to find which option works better and is safer for this group.
MaputoAges 25–49 - NCT06327568Recruiting
Screening for anal cancer and precancer with a new HPV test
This study tests how well a special HPV test (called BD Onclarity™) can find anal cancer or precancer. It is for people at high risk or with known anal abnormalities, and aims to improve early detection.
MilanAges 18 years+ - NCT06345287RecruitingPhase 2
Adaptive radiotherapy after immunotherapy for head and neck cancer
This trial tests a personalized radiotherapy approach after a few rounds of chemo-immunotherapy for people with HPV-negative head and neck cancer. It aims to adjust the radiation dose based on how the tumor responds, possibly reducing side effects while still controlling the cancer.
BeijingAges 18–75 - NCT06420427Recruiting
Blood test to predict cervical cancer return after surgery
This trial uses a simple blood test to look for cancer DNA (ctDNA) and HPV DNA after cervical cancer surgery. The goal is to detect any return of the cancer early, so you and your doctor can act quickly.
Guangzhou, GuangdongAges 18 years+ - NCT06445114RecruitingPhase 2
Blood-Guided Chemoradiation for HPV-Positive Throat Cancer
This study tests whether a blood test that looks for circulating HPV DNA (ctDNA) can help doctors decide if you need chemotherapy after surgery for HPV-positive throat cancer. After you have surgery to remove the cancer, you receive radiation (possibly with chemotherapy) — the results of the blood test guide whether or not to add chemo.
Beverly Hills, CaliforniaAges 18 years+ - NCT06448026RecruitingPhase 2
Cemiplimab and cetuximab before surgery for mouth or throat cancer
This trial tests whether combining two targeted drugs (cemiplimab and cetuximab) before surgery can help people with recurrent mouth or throat cancer that has come back after initial treatment. It aims to see if this approach makes surgery more effective.
Houston, TexasAges 18 years+ - NCT06458062Recruiting
Pocket colposcopy for women with positive HPV test
This study tests a new, smaller device called a pocket colposcope to look at the cervix (the opening of the womb) in women who have had a positive HPV test. The goal is to see if this simpler tool can help find cell changes that might lead to cancer, so you can get treatment sooner.
NairobiAges 25 years+ - NCT06467942Recruiting
Chinese medicine and probiotics for persistent HPV
This trial tests whether a combination of Chinese medicine and a probiotic (Lactobacillus) can help clear a long-lasting HPV infection. It's for women who have had the same high-risk HPV type for over a year and have not developed serious cervical changes.
Beijing, Beijing MunicipalityAges 25 years+ - NCT06500767Recruiting
Emotional impact of counseling before colposcopy
This study looks at how counseling before a colposcopy affects your emotions and mental well-being. You may take part if you have abnormal cervical screening results and need a closer exam.
Turin, TOAges 18 years+ - NCT06513494Recruiting
Health education to boost HPV vaccine in youth
This trial tests whether active health education in schools can increase HPV vaccine coverage among students. It may help protect young people from HPV-related cancers.
Crato, CearáAges 9–14
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Common questions
- Are there clinical trials for hpv?
- Yes. Clin2 currently lists 259 recruiting hpv studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hpv trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hpv trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.