Clinical trials
Hyperbaric Oxygen Therapy clinical trials
Below are recruiting hyperbaric oxygen therapy clinical trials, each written for real people, not researchers. We’re tracking 42 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06452095Recruiting
Hyperbaric oxygen therapy for long COVID brain fog
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) helps with long COVID symptoms, especially brain fog and thinking problems. It may be an option if you have had lingering symptoms for at least 2 months and can travel to one of the study sites.
Toronto, OntarioAges 18 years+ - NCT06128720Recruiting
Hyperbaric oxygen therapy for optic nerve damage
This study tests if breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help people with optic neuropathy, a condition that damages the nerve connecting the eye to the brain.
Palo Alto, CaliforniaAges 18 years+ - NCT05987852Recruiting
Hyperbaric oxygen therapy for ulcerative colitis flare
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) can help people hospitalized with a moderate to severe ulcerative colitis flare get better faster. You will receive the therapy along with standard steroid treatment.
Birmingham, AlabamaAges 18–85 - NCT05842239Recruiting
Hyperbaric oxygen therapy for low sperm count infertility
This trial tests whether breathing 100% oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve fertility in men who have an unexplained low sperm count. It may help by improving sperm health, but you would need multiple sperm tests and to be able to follow the clinic schedule.
ẔerifinAges 21 years+ - NCT05447416Recruiting
Intermittent low-oxygen training versus oxygen chamber training
This study compares two ways of training the body for better aerobic fitness: short, controlled low-oxygen workouts versus treatment in a hyperbaric oxygen chamber. It may help athletes improve endurance, measured by their breathing and fitness performance.
ZrifinAges 18–45 - NCT04647656Recruiting
Hyperbaric oxygen for lingering post-COVID brain fog
This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve long-lasting post-COVID problems with thinking and memory. It may help if your brain symptoms have lasted at least 3 months and affect your daily life.
ẔerifinAges 18 years+ - NCT03964506RecruitingEarly Phase 1
Hyperbaric oxygen plus donor stem cell transplant for blood cancers
This early-phase trial studies whether breathing pure oxygen in a pressurized chamber, along with a donor stem cell transplant, can improve outcomes for certain blood cancers. It may help by supporting the body during transplant and recovery, but it is still being tested for safety and effectiveness.
Rochester, New YorkAges 18–75 - NCT04490317Recruiting
Study follows people with carbon monoxide poisoning in Korea
This study looks at people who have been sickened by carbon monoxide (CO) from an accident or exposure. It aims to better understand what happens over time, which could help improve care and outcomes in the future.
Wŏnju, Gangwon-doAges Any age - NCT06579040Recruiting
Hyperbaric oxygen for endometriosis pain
This trial tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help reduce endometriosis-related pelvic pain. It is for people with ongoing moderate to severe pain who are waiting for surgery.
Toronto, OntarioAges 18 years+ - NCT04791488Recruiting
Testing oxygen level effects after diving or oxygen therapy
This study looks at how breathing extra oxygen (hyperoxia) and the body’s immune response change after diving or when people need hyperbaric oxygen therapy. It may help doctors understand what to expect and how to manage recovery after a diving accident.
ToulonAges 18 years+ - NCT07626450Recruiting
Hyperbaric oxygen after stroke clot removal treatment
This study tests whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help recovery after emergency clot-removal surgery for large blood vessel strokes. The goal is to see if extra oxygen can reduce brain damage and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07558928Recruiting
High-oxygen environment and muscle strength in active adults
This study tests whether exercising in a high-oxygen environment can help build stronger muscles faster. Researchers will have you do resistance training (like weightlifting) in a special chamber with extra oxygen to see if it boosts your muscle gains.
ZrifinAges 18–45 - NCT07430150Recruiting
Long-term effects of oxygen therapy on thinking after brain injury
This study checks if hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) has lasting benefits for thinking skills in people who have had a traumatic brain injury.
ZrifinAges 18 years+ - NCT05697328Recruiting
Testing barotrauma effects of hyperbaric oxygen
This study looks at problems caused by pressure changes during hyperbaric oxygen therapy (HBOT). It may help the team understand risks and how to keep treatment safer while you get HBOT.
Walnut Creek, CaliforniaAges 18 years+ - NCT06055257RecruitingPhase 3
Combination therapy for jaw bone damage after radiation
This trial tests a combination of hyperbaric oxygen therapy and a medication called PENTOCLO to treat osteoradionecrosis (bone damage) in the jaw after radiation treatment for cancer. It may help heal the exposed bone.
Toronto, OntarioAges Any age - NCT06811870RecruitingPhase 1/Phase 2
Hyperbaric oxygen before surgery for breast cancer
This trial tests adding hyperbaric oxygen (breathing pure oxygen in a pressurized chamber) before standard chemotherapy for breast cancer. The goal is to see if it helps shrink the tumor more effectively before surgery.
Guangzhou, GuangdongAges 18–60 - NCT07662629Recruiting
Hyperbaric oxygen and exercise for breast cancer pain
This study tests if adding hyperbaric oxygen therapy (breathing pure oxygen in a special chamber) to a gentle exercise program can help reduce bone, joint, or muscle pain caused by hormone therapy in older women who had breast cancer.
Dokki, Giza GovernorateAges 65–75 - NCT06408363Recruiting
Ear pressure maneuvers for first hyperbaric session
This trial looks at whether doing a specific sequence of ear pressure-equalization moves helps people during their first hyperbaric oxygen therapy session. It might help you if you're about to start this treatment.
Belo Horizonte, Minas GeraisAges Any age
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Common questions
- Are there clinical trials for hyperbaric oxygen therapy?
- Yes. Clin2 currently lists 42 recruiting hyperbaric oxygen therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyperbaric oxygen therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyperbaric oxygen therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.