Clinical trials · Raleigh–Durham, NC
High blood pressure clinical trials in Raleigh–Durham
We’re tracking 39 recruiting high blood pressure studies with a site in or near Raleigh–Durham — including Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Raleigh–Durham
- NCT04930289Enrolling by invitation
Lung transplant registry for better donor lung preservation
This study builds a worldwide database to track and improve how donor lungs are preserved before transplant. Your information may help doctors choose and manage donor lungs more effectively.
Durham, North CarolinaAges Any age - NCT07534501Recruiting
Getting Fresh Produce to Manage Your Health
This study tests whether giving people prescriptions for fresh fruits and vegetables helps them manage high blood pressure, diabetes, or weight—and improves their overall health. You'll get produce and support to eat better.
Durham, North CarolinaAges 18 years+ - NCT07633145Recruiting
Lifestyle Changes to Lower Blood Pressure in Kidney Disease
This study tests whether lifestyle changes—like diet and exercise—can help lower blood pressure in Black adults with moderate kidney disease. It's designed specifically for people at higher risk of kidney problems, and the goal is to see if these changes can slow kidney disease progression and reduce heart disease risk.
Durham, North CarolinaAges 18 years+ - NCT07365332RecruitingPhase 3
IKT-001 for pulmonary arterial hypertension
This study tests a new medicine called IKT-001 for people with pulmonary arterial hypertension (PAH). It aims to see if IKT-001 helps improve exercise ability and other symptoms when added to current PAH therapies.
Durham, North CarolinaAges 18–75 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Durham, North CarolinaAges birth–20 years - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Chapel Hill, North CarolinaAges birth–2 weeks - NCT06002165Enrolling by invitation
Testing Ways to Improve Care for High Blood Pressure in Pregnancy
This study tests ways to help clinics follow a set of best practices for managing severe high blood pressure during and after pregnancy. It wants to see if the new approach helps clinics treat high blood pressure faster and more effectively.
Chapel Hill, North CarolinaAges birth–99 years - NCT06274801RecruitingPhase 3
Long-term study of seralutinib for pulmonary arterial hypertension
This trial is for people with pulmonary arterial hypertension (PAH) who have already completed a previous study of the drug seralutinib. It offers continued access to the treatment so doctors can watch its safety and effects over a longer time.
Chapel Hill, North CarolinaAges 18–75 - NCT06975111RecruitingPhase 2/Phase 3
Improving health during menopause
This trial studies ways to help women during the late menopausal transition. It uses a smartphone app and telehealth visits to track your health and help you feel better.
Chapel Hill, North CarolinaAges 45–55 - NCT06129240Recruiting
Study of a new inhaled treprostinil powder for PH-ILD
This study tests a new dry powder inhaled medicine called LIQ861 for people with pulmonary hypertension related to lung scarring (PH-ILD). If you are already taking an inhaled treprostinil treatment but need better control, this trial may help you switch to a potentially easier-to-use version.
Chapel Hill, North CarolinaAges 18–80 - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Chapel Hill, North CarolinaAges 18–80 - NCT06744231Enrolling by invitation
Thriving Hearts Postpartum Parent Survey
This study is for new parents in certain North Carolina counties who had a baby in the past 6 months. You will fill out a one-time survey to help improve maternity care and support for families.
Chapel Hill, North CarolinaAges 15 years+ - NCT05671406Recruiting
Digital game to help people manage high blood pressure
This study tests whether a sensor-controlled phone/tablet digital game can help people with high blood pressure better take care of their health at home. It may be helpful if you live in a Native American community and are willing to use the technology.
Chapel Hill, North CarolinaAges 18 years+ - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Chapel Hill, North CarolinaAges 18 years+ - NCT06468202RecruitingPhase 4
Aspirin dose study to prevent high blood pressure in pregnancy
This trial compares two doses of aspirin to see which is better at preventing conditions like preeclampsia (a serious form of high blood pressure during pregnancy). You may qualify if you are in early pregnancy and have certain risk factors.
Chapel Hill, North CarolinaAges 14–35
Hear when a new High blood pressure trial opens near Raleigh–Durham, NC
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High blood pressure trials in other cities
Where these studies are running near Raleigh–Durham
Institutions with a site for the recruiting high blood pressure studies listed above.
- University of North Carolina at Chapel Hill · 4 studies
- Duke University Medical Center · 2 studies
- University of North Carolina Chapel Hill · 2 studies
- Duke Lung Transplant Clinic
- Durham VA Health Care System
- Sarah W Stedman Nutrition & Metabolism Center
- UNC
- UNC Hospitals
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting high blood pressure studies in North Carolina.
Common questions
- Are there high blood pressure clinical trials near Raleigh–Durham?
- Yes. We're currently tracking 39 recruiting high blood pressure studies with a site near Raleigh–Durham, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study near Raleigh–Durham?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Raleigh–Durham to take part?
- Not necessarily. These studies have a site near Raleigh–Durham, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open near Raleigh–Durham regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.