Clinical trials
Hyponatremia clinical trials
Below are recruiting hyponatremia clinical trials, each written for real people, not researchers. We’re tracking 12 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06020495RecruitingPhase 3
DDAVP to prevent sodium overcorrection in severe low sodium
This trial tests a medication called DDAVP to prevent the sodium level from rising too quickly when treating severe low sodium in ICU patients. It is for those with dangerously low sodium and neurological symptoms, but without certain other medical conditions.
AmiensAges 18 years+ - NCT04447911RecruitingPhase 4
Empagliflozin for chronic low blood sodium in certain fluid states
This trial studies whether empagliflozin, a blood-sugar–related medicine, can safely improve chronic low blood sodium when you are not too “dry” or have an imbalanced fluid state. It may help stabilize sodium levels and related health symptoms, but you must meet specific blood and organ-function criteria.
WürzburgAges 18 years+ - NCT05542056Recruiting
Test urine markers to predict low sodium from water pills
This study looks for a signal in your urine that could help predict who will develop low blood sodium (hyponatremia) after starting a thiazide-type “water pill.” It may help doctors spot higher-risk people early and adjust care sooner.
MóstolesAges 18 years+ - NCT05692726Recruiting
Tracking salt and fluid balance in low-sodium treatment
This observational study measures how body fluid and electrolytes change in adults with low blood sodium caused by low “tonicity” (not diluted by high sugar or other causes). It may help clinicians better understand which treatment approaches keep sodium levels safer and more stable.
CologneAges 18 years+ - NCT06381934Recruiting
New tests for low sodium from thiazide pills
This study looks at new ways to quickly check how well low sodium (caused by a common water pill called thiazide) is being treated in the hospital. If you have low sodium and take a thiazide pill, this trial may help doctors find better treatment methods.
BaselAges 18 years+ - NCT06821802Recruiting
Protein supplement for low sodium from SIAD
This trial tests if a protein supplement can help patients with low sodium caused by a condition called SIAD. If you have SIAD and low sodium, you may be able to join.
BaselAges 18 years+ - NCT07576036Enrolling by invitation
Study of severe low sodium and brain safety during treatment
This is a retrospective study (meaning researchers look back at medical records) of patients who had very low sodium levels in their blood when admitted to the hospital. Researchers want to understand the link between how quickly doctors correct low sodium and a rare brain condition called osmotic demyelination syndrome.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05973045Recruiting
Warm or cool fluid during hysteroscopy: comfort and safety
This study looks at whether the temperature of the fluid used during hysteroscopy affects image quality, risk of low blood sodium, and pain after the procedure. It may help find a safer, more comfortable way to do hysteroscopy for certain uterine growths.
IzmirAges 18–65 - NCT06408077Recruiting
How sodium levels are managed in kidney failure
This study looks at how the body handles salt (sodium) in people with end-stage kidney disease who are on dialysis. If you join, researchers will test how your body responds to changes in fluids and salt levels.
CologneAges 18 years+ - NCT06646484Recruiting
Using a device to check hydration after brain bleeding
This study tests a new way to monitor your body's water and sodium levels using a simple, painless device (impedancemetry) after a subarachnoid hemorrhage. It may help doctors better manage your hydration and prevent complications during your ICU stay.
Lyon, FranceAges 18 years+ - NCT07273630Recruiting
Protein supplement and drinking less fluid after pituitary surgery
This study tests whether a protein supplement combined with drinking less fluid can help keep sodium levels stable after pituitary surgery. It is designed for patients who are at risk of sodium imbalances after their operation.
BaselAges 18 years+ - NCT07528365Recruiting
Urea Treatment for Low Sodium Levels From SIAD
This trial tests whether urea can help treat dangerously low sodium levels in patients with SIAD (a condition where the body retains too much water) who haven't responded to drinking less fluid. Urea is a naturally occurring substance that may help restore normal sodium balance.
Turin, Piedmont, ItalyAges 18 years+
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Common questions
- Are there clinical trials for hyponatremia?
- Yes. Clin2 currently lists 12 recruiting hyponatremia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hyponatremia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hyponatremia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.