Clinical trials · North Carolina
Kidney Diseases clinical trials in North Carolina
We’re tracking 42 recruiting kidney diseases studies with a site in North Carolina — including Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT05485961RecruitingPhase 2/Phase 3
Clazakizumab for kidney failure patients on dialysis
This study tests an experimental drug called clazakizumab (CSL300) to see if it can reduce inflammation and lower the risk of heart problems in people with kidney failure who are on dialysis. It may help if you have diabetes or heart disease and have high inflammation levels.
Charlotte, North CarolinaAges 18 years+ - NCT05828823Recruiting
Two-times-a-week dialysis for new patients
This study tests whether starting dialysis at twice a week, instead of the usual three times, is safe and effective for people who still have some kidney function. If the kidneys still make urine and clear waste, being on dialysis less often may maintain that function longer.
Chapel Hill, North CarolinaAges 18 years+ - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Charlotte, North CarolinaAges 40–80 - NCT06839833Recruiting
APOL1 gene test study for trial volunteers
This study checks if a new genetic test for the APOL1 gene works correctly. It uses samples from people who have already joined another drug trial.
Durham, North CarolinaAges 18–70 - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Kinston, North CarolinaAges 18 years+ - NCT04160507Recruiting
Biobank study collecting samples about kidney health in Black adults
This study builds a research “bank” (biorepository) of blood and other samples from Black adults with different stages of kidney health, including people with kidney disease and people without known kidney disease. It may help researchers better understand kidney risk and causes over time.
Durham, North CarolinaAges 18 years+ - NCT05832229RecruitingPhase 2
Studying rosuvastatin to slow liver scarring in cirrhosis
This Phase 2 trial tests whether rosuvastatin (a cholesterol-lowering medicine) can improve how well the liver functions and slow worsening scarring in people with cirrhosis. It also checks for side effects and safety.
Durham, North CarolinaAges 18–75 - NCT05997875Recruiting
Learning about dialysis access options
This study tests a new way to teach people about hemodialysis and the access (the spot in your arm or leg where the dialysis machine connects). It is for people with advanced kidney disease who are considering hemodialysis and want to learn about their options for vascular access.
Chapel Hill, North CarolinaAges 18 years+ - NCT07515794Enrolling by invitation
Long-term follow-up for transplant access study participants
This is a follow-up study for people who already participated in the STEPS research project about improving fairness in organ transplants. Researchers want to track how participants are doing over time and learn more about transplant outcomes.
Winston-Salem, North CarolinaAges 18–75 - NCT06906627Recruiting
Improving kidney screening for people with diabetes
This study helps people with type 2 diabetes get the right kidney tests to catch kidney problems early. Your doctor will check your kidney health through a simple blood and urine test.
Houston, North CarolinaAges 18 years+ - NCT06906640Recruiting
Improving Kidney Care for People with Type 2 Diabetes
This study tests a program to help primary care doctors better screen and manage kidney problems in people with type 2 diabetes. It aims to see if using recommended medicines can slow kidney disease and improve health.
Durham, North CarolinaAges 18 years+ - NCT01016613Recruiting
Kidney health study that helps build a tissue and data bank
This study collects health information and biological samples to better understand kidney disease and support future kidney research. It may help your care indirectly by improving how kidney conditions are recognized and studied.
Charlotte, North CarolinaAges Any age - NCT05793138Enrolling by invitation
Care model for older adults on dialysis at home
This trial tests a geriatric (older-adult) care approach to support people age 55+ who receive dialysis while living in the community. It may help improve how care is coordinated for older adults, including those with mild to moderate memory or thinking problems.
Durham, North CarolinaAges 55 years+ - NCT06027788Recruiting
Embolic protection during heart valve surgery
This trial tests a device that may help protect your brain from small particles during heart valve surgery. It is for people 60 and older having certain types of valve replacement or repair.
Durham, North CarolinaAges 60 years+ - NCT01209000Recruiting
Study for children with new kidney protein loss
This study is for children (and some newly diagnosed patients) who have nephrotic syndrome—kidneys leaking a lot of protein. It aims to better understand the kidney condition (sometimes using biopsy) and support future care decisions.
Winston-Salem, North CarolinaAges Up to 80 years - NCT06918990RecruitingPhase 1
CarBel for antibody-mediated rejection after kidney transplant
This study tests a new drug called CarBel to treat antibody-mediated rejection in kidney transplant patients. The goal is to see if it can help stop the rejection and protect your new kidney.
Durham, North CarolinaAges 18–75 - NCT05917522RecruitingPhase 2
Biomarker-guided changes to anti-rejection medicines after kidney transplant
This Phase 2 study looks at whether blood test “biomarkers” can guide safely changing anti-rejection medicines after an ABO-compatible kidney transplant. It may help some people reduce certain medicines while keeping the new kidney protected from rejection.
Durham, North CarolinaAges 18–70 - NCT06055608RecruitingPhase 2
Improving kidney transplant outcomes in teens and young adults
This trial tests a new approach to help teenagers and young adults keep their first kidney transplant working well. It looks at how to improve long-term success by carefully managing the immune system around the time of transplant.
Durham, North CarolinaAges 13–20
Where these studies are running in North Carolina
Institutions with a site for the recruiting kidney diseases studies listed above.
- Duke University Medical Center · 5 studies
- Duke University · 4 studies
- University of North Carolina at Chapel Hill · 3 studies
- Levine Children's Hospital · 2 studies
- Wake Forest University Health Sciences · 2 studies
- Almac Diagnostic Services LLC
- Atrium Health Department of Family Medicine Research
- Atrium Health Wake Forest Baptist Medical Center (Wake Forest Baptist)
What taking part in a kidney diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Kidney Diseases trials in other states
Common questions
- Are there kidney diseases clinical trials in North Carolina?
- Yes. We're currently tracking 42 recruiting kidney diseases studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a kidney diseases study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a kidney diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New kidney diseases studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.