Clinical trials · North Carolina
Kidney Diseases clinical trials in North Carolina
We’re tracking 42 recruiting kidney diseases studies with a site in North Carolina — including Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Chapel Hill, North CarolinaAges 18 years+ - NCT06717698RecruitingPhase 2
Testing a new medicine for kidney damage in chronic kidney disease
This study tests different doses of an investigational medicine (NNC0519-0130) to see if it can reduce kidney damage in people with chronic kidney disease. It may be an option for you if you have kidney impairment and either have or don't have type 2 diabetes.
Morehead City, North CarolinaAges 18 years+ - NCT04752293Recruiting
Study of a kidney blood-pressure system in kids
This study looks at how a kidney-related blood-pressure system works in children and teenagers, comparing those with newly diagnosed primary (no known cause) high blood pressure to those with normal blood pressure. It may help doctors better understand childhood blood-pressure changes and guide future care.
Winston-Salem, North CarolinaAges 7–18 - NCT07355296RecruitingPhase 2
Testing BI 764198 in adults and teens with kidney disease
This study tests an investigational drug (BI 764198) in adults and teens with different types of kidney disease. The goal is to see if the drug can help slow kidney damage. You may be able to join if your kidney function is at a certain level, you are on stable blood pressure medications, and you haven't had recent strong immune treatments.
Durham, North CarolinaAges 12 years+ - NCT07271186RecruitingPhase 2
Study of an experimental drug for kidney disease from type 2 diabetes
This study tests an investigational drug called ALN-ANG3 to see if it can help people with diabetic kidney disease. The drug may reduce kidney damage and slow down the loss of kidney function. If you join, you will get the study drug or a placebo (a dummy shot) and be followed by a study doctor.
Greenville, North CarolinaAges 18–80 - NCT06830629RecruitingPhase 2
MZE829 for APOL1 kidney disease
This trial tests an experimental drug called MZE829 for people with kidney disease linked to the APOL1 gene. It aims to see if the drug can help protect kidney function.
Fayetteville, North CarolinaAges 18–68 - NCT06738394Recruiting
Exercise study for older adults with kidney disease
This study tests whether a supervised exercise program can help older adults with chronic kidney disease improve their physical function and stay active. You have to be able to do exercise and not be on dialysis.
Winston-Salem, North CarolinaAges 65–100 - NCT05312879RecruitingPhase 2/Phase 3
Test drug VX-147 for APOL1-related protein in urine kidney disease
This trial studies whether VX-147 can improve kidney disease caused by an APOL1 gene change, which often leads to protein leaking into the urine. It includes both adults and children and focuses on safety and effectiveness over time.
Cary, North CarolinaAges 10–65 - NCT07753993RecruitingPhase 3
Study of elecoglipron for chronic kidney disease
This trial tests an investigational medicine called elecoglipron for people with chronic kidney disease. It aims to see if it can improve kidney health compared to a placebo (inactive pill) and may be an option for those already on standard blood pressure and kidney protective medications.
Greensboro, North CarolinaAges 18 years+ - NCT04741646RecruitingPhase 2
Ferric citrate for kids with chronic kidney disease
This Phase 2 study tests ferric citrate, a medicine that helps control phosphate and iron balance, in children with chronic kidney disease. It may help slow problems related to kidney disease by improving lab measures like phosphate levels.
Durham, North CarolinaAges 6–18 - NCT07231679RecruitingPhase 1/Phase 2
Study of IGT-303 for diabetic kidney disease
This study tests an investigational drug called IGT-303 in people with chronic kidney disease caused by type 2 diabetes. It aims to see if the drug is safe and helpful for slowing kidney damage.
Statesville, North CarolinaAges 18–75 - NCT06902558RecruitingPhase 2
Study of ABBV-CLS-628 for adults with polycystic kidney disease
This trial tests a new drug, ABBV-CLS-628, for people with autosomal dominant polycystic kidney disease (ADPKD). The goal is to see if it slows kidney function decline and is safe to use.
Chapel Hill, North CarolinaAges 18–55 - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Greenville, North CarolinaAges 18 years+ - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Chapel Hill, North CarolinaAges 18–80 - NCT07393594Enrolling by invitation
Tracer study for kidney transplant monitoring
This study looks at a new blood test to help monitor the health of your transplanted kidney and check for early signs of rejection. The test will be done as part of your usual care after a kidney transplant.
Greenville, North CarolinaAges 18 years+ - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Charlotte, North CarolinaAges 18–90 - NCT07033117Recruiting
Improving kidney transplant access with RaDIANT
This trial tests if a special program helps dialysis centers refer more people to large transplant centers for a kidney transplant.
Durham, North CarolinaAges 18–80 - NCT06798909RecruitingPhase 3
CMV prevention in kidney transplant patients
This trial tests two ways to prevent CMV in kidney transplant patients who are at high risk. It compares giving antiviral medicine preemptively (based on regular blood tests) versus giving it as prophylaxis (starting right after transplant). The goal is to see which approach prevents CMV infection better.
Durham, North CarolinaAges 18 years+ - NCT06001827Recruiting
Study of a wrap to help new dialysis access points heal
This trial tests a special wrap placed around a new arm access point for dialysis (called an AV fistula) to see if it helps the access stay healthy and work better. It is for people who need a new AV fistula for kidney dialysis.
Charlotte, North CarolinaAges 18 years+ - NCT06963827RecruitingPhase 3
Study of mezagitamab for IgA nephropathy
This trial tests a new drug called mezagitamab for adults with IgA nephropathy, a kidney condition. The study aims to see if this drug can help reduce protein in the urine and preserve kidney function. You may be eligible if your kidney function is above a certain level and your urine protein is high enough.
Winston-Salem, North CarolinaAges 18 years+ - NCT05931276RecruitingPhase 3
Beta blocker choice may improve heart outcomes on dialysis
This phase 3 study tests whether a specific beta blocker selection on hemodialysis can improve cardiovascular outcomes. It focuses on certain beta blockers commonly used through the VA pharmacy and compares them in a randomized way.
Durham, North CarolinaAges 18 years+ - NCT07153939Recruiting
Study of a new device to create dialysis access
This trial tests a new device called the Velocity pAVF System that creates a connection between a vein and artery in your arm for hemodialysis. If you need dialysis now or within the next 6 months, this could be a new option for you.
Charlotte, North CarolinaAges 18–80 - NCT04634916Recruiting
Check how a dialysis fistula device performs in real life
This study monitors how well the BD WavelinQ endoAVF device works after routine clinical use. It may help people who need a dialysis access fistula by sharing real-world safety and performance data.
Raleigh, North CarolinaAges 18 years+ - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Chapel Hill, North CarolinaAges birth–2 weeks
Where these studies are running in North Carolina
Institutions with a site for the recruiting kidney diseases studies listed above.
- Brookview Hills Research Associates · 3 studies
- Duke University Medical Center · 3 studies
- Research Site · 3 studies
- Brookview Hills Research Associates, LLC · 2 studies
- Surgical Specialists of Charlotte · 2 studies
- Wake Forest University Health Sciences · 2 studies
- Carteret Medical Group
- Duke
What taking part in a kidney diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Kidney Diseases trials in other states
Common questions
- Are there kidney diseases clinical trials in North Carolina?
- Yes. We're currently tracking 42 recruiting kidney diseases studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a kidney diseases study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a kidney diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New kidney diseases studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.