Clinical trials
Lipodystrophy clinical trials
Below are recruiting lipodystrophy clinical trials, each written for real people, not researchers. We’re tracking 13 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03553420Recruiting
Registry for people with lipodystrophy
This is a study that keeps a medical record (a registry) of people with lipodystrophy, a condition where body fat is missing or unevenly distributed. It may help researchers understand different causes and patterns of the condition over time.
ViennaAges Any age - NCT06484868RecruitingPhase 4
Study of metreleptin for partial lipodystrophy
This trial tests an open-label study of metreleptin in people with partial lipodystrophy, a condition where fat is lost from some areas of the body. The goal is to see if the drug can help manage related health problems.
LilleAges 12 years+ - NCT07091734RecruitingPhase 2
Tirzepatide for partial lipodystrophy: a new treatment study
This trial is testing a medication called tirzepatide (Mounjaro) to see if it can help people with a rare fat disorder called familial partial lipodystrophy. The study hopes to improve blood sugar control and lower triglycerides, which are often high in this condition.
Ann Arbor, MichiganAges 18 years+ - NCT07220785RecruitingPhase 3
Testing mibavademab for generalized lipodystrophy in adults and children
This trial tests a new drug called mibavademab for people with generalized lipodystrophy, a condition where the body can't store fat properly, leading to problems like diabetes and high triglycerides. It aims to see if the drug safely improves these metabolic issues.
Ann Arbor, MichiganAges 2 years+ - NCT06679270RecruitingPhase 3
Long-term safety study of metreleptin for partial lipodystrophy
This study tests the long-term safety of metreleptin for people with partial lipodystrophy. It is for those who already completed a related study and want to continue treatment.
Birmingham, AlabamaAges 13 years+ - NCT02325674Recruiting
Metreleptin safety and effectiveness registry
This registry follows people who are already taking metreleptin (a medicine for certain rare conditions) to better understand its long-term safety and how well it works in everyday use. It may help you and other patients by building real-world evidence about this treatment.
Birmingham, AlabamaAges Any age - NCT03900286Recruiting
Testing a low-calorie diet for partial fat loss diabetes
This trial studies whether a low-calorie (low energy) diet can improve diabetes control in adults with familial partial lipodystrophy. It likely helps by changing how your body handles blood sugar and fat use, but you must meet specific safety and eligibility checks.
CambridgeAges 18–99 - NCT05419037Recruiting
Study of pregnancy outcomes in people with lipodystrophy
This study looks at how pregnancy goes and what birth outcomes happen in women with lipodystrophy, comparing those who used metreleptin during pregnancy versus those who did not. It also collects information and blood samples from the children so researchers can better understand the effects of metreleptin during pregnancy.
Bethesda, MarylandAges 6 months–98 years - NCT05996536Recruiting
Fat labeling study in familial partial lipodystrophy
This study tests a safe way to label fat (triglycerides) in people with a rare condition called familial partial lipodystrophy (FPL), where fat is missing in some areas. It involves two small fat biopsies, one from the belly and one from the thigh, to understand how the body handles fat.
Bethesda, MarylandAges 18–65 - NCT03087253Recruiting
Study of what causes and affects lipodystrophy
This study observes people with lipodystrophy to better understand how the condition develops and affects the body over time. It may help researchers learn who is most affected and guide future treatments.
Bethesda, MarylandAges Any age - NCT07412028Recruiting
Gene study in women with severe insulin resistance and PCOS
This study is looking for women with a type of severe insulin resistance linked to genetics, especially those who have PCOS or a condition called lipodystrophy. The goal is to better understand the genes involved so doctors can offer more targeted treatments.
ParisAges 18–45 - NCT05470504RecruitingPhase 2
Pegvisomant for severe insulin resistance from rare fat or gene problems
This Phase 2 study tests pegvisomant, a medicine that blocks growth hormone, to see if it can improve severe insulin resistance in people with a specific genetic cause or a rare fat distribution condition. If you fit the rare diagnosis, the study may help clarify whether growth-hormone blocking can improve blood sugar and related health markers.
Bethesda, MarylandAges 18–70 - NCT06236932Recruiting
Infection risk in obesity study
This study looks at how obesity and related conditions affect your body's ability to fight infections. It may help find ways to prevent illness in people with obesity.
NaplesAges 18–65
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Lipodystrophy trials by city
Studies with a site in or near these metro areas.
Lipodystrophy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for lipodystrophy?
- Yes. Clin2 currently lists 13 recruiting lipodystrophy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lipodystrophy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lipodystrophy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.