Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,252 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03175471Recruiting
MRI study of blood-vessel and tissue signs in child liver disease
This trial uses MRI scans to look for “biomarkers,” which are measurable signs in the liver, to better understand autoimmune liver diseases in children and teens. It may help doctors track disease and improve care by finding imaging patterns linked to illness.
Cincinnati, OhioAges 6–23 - NCT07765823Recruiting
N-acetylcysteine for liver failure not caused by acetaminophen
This trial tests whether the drug N-acetylcysteine (NAC) can help people with sudden liver failure that is not caused by acetaminophen (like Tylenol). If you qualify, you may receive NAC, which might help your liver recover.
Lahore, Punjab ProvinceAges 18–60 - NCT04874428RecruitingPhase 1
Blood thinner pills in people with mild-to-moderate cirrhosis
This early study tests whether the blood thinner pills rivaroxaban and apixaban can be used safely in people with liver cirrhosis that is not too severe. It may help doctors understand the safest way to prevent or treat blood clots in this group.
BernAges 18 years+ - NCT07740382Recruiting
Pain block comparison for recovery after liver surgery
This study compares two types of pain-relieving nerve blocks used during liver surgery to see which one helps you breathe better and recover more comfortably after the operation.
Alexandria, Sbein-ElkomAges 18–75 - NCT07227012RecruitingPhase 1/Phase 2
Study of a new drug for advanced liver cancer
This trial tests a new medicine, PF-08634404, alone or with other treatments for adults with advanced liver cancer that cannot be removed by surgery or has spread. It is for people who have not had prior systemic therapy and have good liver function.
Irvine, CaliforniaAges 18 years+ - NCT06873165Recruiting
Gut bacteria treatment for fatty liver disease
This study tests whether a specially designed gut bacteria treatment can help people with fatty liver disease and related health issues like high blood sugar, high cholesterol, or high blood pressure. It aims to see if the treatment is safe and improves liver health.
TaipeiAges 18–70 - NCT07760038Recruiting
Phycocyanin for liver protection before partial liver removal
This trial tests whether phycocyanin, a natural supplement, can protect the liver before and after surgery to remove part of the liver. It is for people with a type of bile duct cancer who are already getting chemotherapy and other treatments before surgery.
Hangzhou, ZhejiangAges 18–75 - NCT06549829Recruiting
Nutrition coaching before liver cancer surgery
This trial tests whether getting special nutrition support before surgery helps patients with liver cancer recover better and have fewer complications. It may help you feel stronger and heal faster after your operation.
Hangzhou, ZhejiangAges 18–80 - NCT07277322RecruitingPhase 1/Phase 2
Two immunotherapy drugs before surgery for MSS colorectal cancer with liver spots
This trial tests a combination of two immunotherapy drugs (Dupilumab and Toripalimab) before surgery for people with MSS colorectal cancer that has spread to the liver. The goal is to see if this treatment can shrink the liver tumors and help the body's immune system fight the cancer.
New York, New YorkAges 18 years+ - NCT07713758RecruitingPhase 1
How the body handles repinatrabit with liver or kidney issues
This trial checks how repinatrabit is processed in people with moderate liver problems or severe kidney problems compared to healthy adults. It helps doctors understand if the dose should be adjusted for these conditions.
Miami, FloridaAges 18–65 - NCT07279350Recruiting
Health advocate support for children after liver transplant
This study tests whether having a health advocate helps families manage care for their child after a liver transplant. The advocate will provide support and resources to reduce stress and improve the child's recovery.
San Francisco, CaliforniaAges birth–18 years - NCT07159048Recruiting
Heat therapy for liver tumors
This trial tests a heat-based treatment for liver cancer tumors that uses multiple methods to destroy cancer cells. It may help people with liver tumors that haven't spread and who are healthy enough for treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT03884075RecruitingPhase 2
Semaglutide study for fatty liver and how sugar affects the liver
This Phase 2 study tests how semaglutide (a diabetes medication also used for weight) affects fatty liver and the liver’s response to sugar. It may help people with non-alcoholic fatty liver disease understand whether the drug improves liver fat and related changes.
Bethesda, MarylandAges 18–100 - NCT06808945Recruiting
Prehabilitation program for liver transplant patients
This study tests a pre-surgery exercise and nutrition program (prehabilitation) for people waiting for a liver transplant. It aims to see if getting stronger before surgery can help you recover better after the transplant.
RotterdamAges 18 years+ - NCT06781502Recruiting
Liver Disease and Transplant Study
This study is creating a database of people with severe liver problems or who have had a liver transplant. The goal is to learn more about these conditions and improve care.
Bologna, BolognaAges 18 years+ - NCT06342557Recruiting
App-Based Health Diary for Young Liver Transplant Patients
This study uses an app (ePRO Diary) to track your health after a liver transplant or while waiting for one. It’s designed for young people between 14 and 20 years old who are moving from pediatric to adult care.
Bergamo, MILANOAges 14–20 - NCT06257407Recruiting
Managing bleeding during and after liver transplant
This trial studies how doctors manage bleeding before, during, and after liver transplant surgery. The goal is to improve safety and outcomes for people receiving a new liver.
BesançonAges 18 years+ - NCT05866796Recruiting
Test blood patterns to predict problems after liver transplant
This study checks whether a special blood test can predict who is at higher risk of graft loss (the transplanted liver not working well) and death after a liver transplant. It may help doctors identify higher-risk patients earlier and tailor follow-up care.
Ghent, FlandersAges 18 years+ - NCT07010315Recruiting
Educational tool for liver cancer prevention
This trial tests an educational tool designed to help people learn about preventing liver cancer. It is for adults who are patients at the HOPE Clinic and can use a smartphone or computer.
Houston, TexasAges 18 years+ - NCT07082439RecruitingPhase 2
Pembrolizumab and Odetiglucan for Liver-Dominant Colorectal Cancer
This study tests a combination of two drugs, pembrolizumab and odetiglucan, in people whose colorectal cancer has spread mainly to the liver and has not responded to standard treatments. The goal is to see if this combination can shrink or slow the growth of liver tumors.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06848842RecruitingPhase 2
Ivonescimab and chemotherapy for colorectal cancer that spread only to the liver
This trial tests a new drug called ivonescimab combined with chemotherapy for people whose colorectal cancer has spread only to the liver and cannot be surgically removed right away. The goal is to see if this combination can shrink the tumors enough to allow surgery or other treatments.
BeijingAges 18 years+ - NCT06559878Enrolling by invitation
Liver Mitochondria Study in Fatty Liver Disease
This study looks at how the liver's mitochondria (the energy powerhouses of cells) work in people with fatty liver disease. Participants will have an MRI scan and receive a small amount of fat solution through an IV to see how the liver processes fat.
Helsinki, UusimaaAges 18–75 - NCT06534840Recruiting
Predicting lung problems after liver transplant
This study uses a computer program to predict lung problems after a liver transplant. It may help doctors better care for people like you.
Chengdu, SichuanAges 18–80 - NCT06506513Recruiting
Can exercise help fatty liver disease?
This study tests whether a program of physical activity can reduce fat in the muscles and liver of people with MASLD, a type of fatty liver disease linked to metabolism. It looks at how exercise might help improve liver health.
BrusselsAges 18–70
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,252 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.