Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,254 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06534840Recruiting
Predicting lung problems after liver transplant
This study uses a computer program to predict lung problems after a liver transplant. It may help doctors better care for people like you.
Chengdu, SichuanAges 18–80 - NCT06506513Recruiting
Can exercise help fatty liver disease?
This study tests whether a program of physical activity can reduce fat in the muscles and liver of people with MASLD, a type of fatty liver disease linked to metabolism. It looks at how exercise might help improve liver health.
BrusselsAges 18–70 - NCT06462742Recruiting
Microwave ablation vs. surgery for intrahepatic cholangiocarcinoma
This trial compares two treatments for a liver cancer called intrahepatic cholangiocarcinoma—surgery to remove the tumor versus microwave ablation, which uses heat to destroy cancer cells. It tests if ablation works as well as surgery for people with small tumors that haven't spread.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06318949Recruiting
Albumin changes as early signs of chronic liver disease
This study is looking at whether changes in a protein called albumin can help find liver disease earlier. It is for people who have some liver scarring but no serious complications.
AngersAges 18 years+ - NCT05879159Recruiting
Faster home recovery after minimally invasive liver surgery
This trial studies an “enhanced recovery” plan to help some people go home sooner after minimally invasive (often robotic) liver surgery. It aims to improve comfort and outcomes while making early discharge possible for carefully selected patients.
Houston, TexasAges 18 years+ - NCT04798898Recruiting
RFA plus immune stimulation during liver surgery for colon cancer spread
This trial looks at whether using a heat-based treatment (RFA) to trigger the immune system before or during liver surgery can improve outcomes for people with colon cancer that has spread to the liver. It’s aimed at people who plan to have the liver tumors removed because they look treatable.
AarhusAges 18–99 - NCT05057052RecruitingPhase 2
Freezing liver tumors with immunotherapy and a pill drug
This Phase 2 trial tests whether freezing (cryoablation) plus sintilimab (an immune system medicine) and regorafenib (a pill) can shrink colorectal cancer that has spread to the liver. It is for people whose cancer has come back or progressed after at least two prior chemotherapy treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05098847RecruitingPhase 2
Freezing liver tumors plus anti-cancer drugs for spread cancer
This trial tests whether freezing (cryoablation) liver metastases works better when combined with immunotherapy (sintilimab) and a targeted pill (lenvatinib). It’s for people whose cancer has spread to the liver and has not responded to earlier treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05035108RecruitingEarly Phase 1
Bioartificial liver treatment using hiHep cells after liver surgery
This early-stage study tests a lab-made “bioartificial liver” (using hiHep cells) after major liver surgery to help the remaining liver recover. It may help people whose remaining liver volume after resection is less than half and who have acceptable heart, lung, and blood test results for surgery.
Hangzhou, ZhejiangAges 30–80 - NCT05106322Recruiting
Using a hand scanner to check fat buildup in liver grafts
This study tests whether an on-site, hand-held scanner during surgery can estimate fat-related liver changes in donated liver tissue. It may help surgeons better assess the quality of liver grafts while the transplant is happening.
VillejuifAges 18 years+ - NCT05655273Enrolling by invitationPhase 4
Switch tacrolimus timing after liver transplant to Envarsus
This trial looks at whether changing your maintenance anti-rejection medicine from Prograf (usually twice daily) to Envarsus (once daily) can help keep your liver and kidney function stable. It targets people who may be having kidney side effects, symptoms from tacrolimus, or trouble taking a twice-daily medicine.
Toronto, OntarioAges 18–99 - NCT04020276Recruiting
Adaptive MRI radiation for liver metastases
This study tests a radiation treatment that uses real-time MRI (an imaging scan) to guide the dose for liver metastases. It may help control tumors while aiming to better protect nearby healthy liver tissue.
Madison, WisconsinAges 18 years+ - NCT05613010Recruiting
Tech tools to help young transplant patients take meds correctly
This study tests technology (like text reminders and an electronic pill box) to help adolescents and young adults who received a kidney or liver transplant take their medicines every day. It may help protect the transplant by improving medication adherence.
Baltimore, MarylandAges 13–25 - NCT05428735Recruiting
Liver-first treatment study for colorectal cancer spread to liver
This trial studies a “liver-first” approach for colorectal cancer that has spread mainly to the liver, to see if it can help more people have the tumor(s) removed or treated. You may be eligible if your liver involvement is too extensive for immediate surgery but could become treatable after a specific plan.
New Haven, ConnecticutAges 18 years+ - NCT05062317RecruitingPhase 2
Blood test-guided chemotherapy after liver tumor removal
This trial uses a blood test (ctDNA, a sign of cancer cells shedding into the blood) to help guide chemotherapy after surgery to remove colorectal liver metastases. It may help patients get the right chemotherapy plan after their operation, potentially based on whether cancer material is still detectable.
Houston, TexasAges 18 years+ - NCT04378023Recruiting
Liver transplant plus chemo-radiation for bile duct cancer
This study tests giving chemo and radiation before a liver transplant for an unresectable bile duct cancer near the liver (hCCA). If your cancer can’t be removed with surgery right now, this approach aims to shrink and control it so transplant may become an option.
Barcelona, BarcelonaAges 18–70 - NCT04143516RecruitingPhase 2/Phase 3
Test tissue testing right after liver tumor ablation
This study looks at liver metastases treated with a procedure that destroys tumors (ablation) and then checks tumor tissue right away. The team wants to see whether the tissue results can guide immediate retreatment to better control cancer in the liver.
New York, New YorkAges 18 years+ - NCT04520737Recruiting
Exercise coaching during chemotherapy for liver metastases
This trial studies whether a “prehab” program—structured exercise and preparation—can help people keep up function while they are on chemotherapy for colorectal cancer that has spread to the liver. If you can safely exercise, the program may help you tolerate treatment and stay active.
TarragonaAges 18 years+ - NCT04645251Recruiting
Join a UK registry for polycystic liver disease
This registry is for people with polycystic liver disease who have a high number of liver cysts. It helps collect information about your condition to better understand and support future care.
NijmegenAges 18 years+ - NCT03474822RecruitingPhase 1/Phase 2
Plasmodium immune treatment for breast and liver cancers
This early-phase study tests an immune-based treatment (using Plasmodium) for people with advanced breast cancer or advanced liver cancer. It aims to see whether the treatment is safe and whether it can help the body’s immune system fight the cancer.
Guangzhou, GuangdongAges 18–70 - NCT02060565Recruiting
Test noninvasive scans to diagnose chronic liver disease
This study looks at how well noninvasive tests (tests that don’t require surgery, like scans and blood-based measurements) can diagnose chronic liver disease in people with certain liver conditions. It may help doctors choose better, less invasive ways to identify the type and stage of liver problems.
PessacAges 18 years+ - NCT06075745RecruitingPhase 2
CMV Vaccine Study for Liver Transplant Candidates
This trial tests a vaccine to prevent cytomegalovirus (CMV) infection in people awaiting a first liver transplant. You may be eligible if you have never been infected with CMV and are scheduled to receive a liver transplant within the next 1 to 12 months.
Birmingham, AlabamaAges 18 years+ - NCT07656181Recruiting
Standardizing quality criteria for liver ultrasound with contrast
This trial gathers expert doctors to create standard quality rules for liver ultrasound exams that use contrast dye. If you're a very experienced ultrasound doctor, your opinion could help shape future care.
Bern, Canton of BernAges Any age - NCT06533592Recruiting
Bile duct connection technique in liver transplant
This study compares two ways of connecting the bile duct during a liver transplant to see which leads to a smoother recovery. It is for adults having a planned first transplant from a deceased donor.
Warsaw, Masovian VoivodeshipAges 18–75
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,254 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.