Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07253389Recruiting
Comparing two TIPS techniques to prevent variceal rebleeding in cirrhosis
This trial tests a slightly smaller TIPS stent (underdilated) against the standard size to see which is better at preventing another variceal bleed in people with cirrhosis and liver scarring. It aims to find the safest way to lower pressure in the veins while reducing side effects.
Xi'an, ShaanxiAges 18–75 - NCT07252076Recruiting
MRI for detecting hidden liver metastases in pancreatic cancer
This trial uses an MRI scan to look for small liver metastases that may not be visible on a CT scan in people newly diagnosed with pancreatic cancer. It aims to improve the accuracy of staging before treatment begins.
Alessandria, PiedmontAges 18 years+ - NCT07248371Recruiting
Validating multi-omics for metabolic syndrome diseases
This study is testing a new way to look at health information (multi-omics) to better understand conditions related to metabolic syndrome, like diabetes or heart disease. It may help doctors find more personalized treatments.
TaoyuanAges 20 years+ - NCT07248722Enrolling by invitation
Pantoprazole after preventive variceal treatment
This trial tests whether a heartburn medication (pantoprazole) helps patients with liver cirrhosis who have had a procedure to treat enlarged veins in the esophagus or stomach. It looks at how well the medicine works when given after this procedure to prevent complications.
Shenyang, LiaoningAges 18 years+ - NCT07246421Recruiting
Glucagon resistance in fatty liver and diabetes
This study looks at how people with fatty liver and type 2 diabetes respond to glucagon, a hormone that helps control blood sugar. It may help researchers understand a condition called 'glucagon resistance' and find better treatments.
AarhusAges 30–70 - NCT07246668RecruitingPhase 2
Carbon ion radiation with immunotherapy for advanced liver cancer
This trial tests a combination of carbon ion radiation therapy with two drugs, atezolizumab and bevacizumab, for people with advanced liver cancer that cannot be surgically removed. The goal is to see if this approach is safe and effective.
SeoulAges 20 years+ - NCT07231991RecruitingPhase 1
How the body processes Vepdegestrant in liver impairment
This study tests how the drug Vepdegestrant is processed by people with different levels of liver function. It aims to understand if liver problems change how the drug works, which can help doctors give the right dose.
Miami, FloridaAges 18–70 - NCT07237750Recruiting
Weight loss trial: endoscopy procedure vs lifestyle changes
This study compares a new endoscopic procedure (a stomach tightening treatment done through a tube in your mouth) with a structured diet and exercise program to help with weight loss. It is for Asian adults who have tried and failed to lose weight before.
Beijing, Beijing MunicipalityAges 18–65 - NCT06899854Recruiting
Collecting blood and tissue from patients with liver cancer
This study collects blood and tumor tissue samples from people with primary liver cancer who are starting their first treatment (systemic therapy or surgery). The samples help researchers learn more about these cancers and how to improve future treatments.
Pavia, PaviaAges 18–90 - NCT06898398Recruiting
TACE before surgery for large liver cancer
This trial combines a procedure called TACE (which blocks the blood supply to the tumor) with surgery to remove a large liver tumor. It is for people newly diagnosed with a large liver cancer that hasn't spread and can be completely removed with surgery.
Beijing, Beijing MunicipalityAges 18–75 - NCT06908785Recruiting
Blood test to predict bleeding risk after procedures in cirrhosis
This trial is testing if a special blood test called ROTEM can help doctors predict the risk of bleeding after high-risk procedures in people with cirrhosis. It aims to improve safety and guide treatment decisions.
Santander, CantabriaAges 18–65 - NCT06372015Recruiting
Diet program vs bariatric surgery for liver health
This study compares two ways to help people with obesity and liver problems: a special diet program or weight-loss surgery. Researchers will look at changes in fats, immune system, and genetic markers to see which approach works better.
Castellana Grotte, BariAges 18 years+ - NCT07225114RecruitingPhase 2
Better ultrasound imaging with contrast before biopsy
This trial tests a new, detailed ultrasound technique that uses a contrast agent (called Definity) to get clearer images of a suspicious area before a biopsy. It may help doctors better see the blood flow in the lesion, which could improve diagnosis.
Chapel Hill, North CarolinaAges 18 years+ - NCT07222813Recruiting
Liver scan to detect high blood pressure in the heart
This trial uses a special liver scan (FibroScan) to measure liver stiffness, which may help detect high pressure in the central veins returning blood to the heart. It is for people with heart failure who are already scheduled for a right heart catheterization.
Los Angeles, CaliforniaAges 18 years+ - NCT01757730Recruiting
MRI test to measure soft tissue stiffness
This trial uses a special type of MRI to estimate how stiff certain soft tissues are in the body. You may benefit by helping doctors better measure tissue stiffness, which can relate to different health problems.
Columbus, OhioAges 18 years+ - NCT06844357RecruitingPhase 2/Phase 3
New embolization vs standard for liver cancer
This trial tests a new embolization treatment (TATE) against standard therapy for people with intermediate-stage liver cancer that hasn't spread. The goal is to see if TATE works better at controlling the tumor.
Nanjing, JiangsuAges 18 years+ - NCT06914635Recruiting
Immunotherapy hub study for liver tumor patients
This trial is checking how the immune system works in people with primary liver cancer, looking at ways to prevent infections and manage the tumor. It is an observational study—meaning no new treatments are given—so it helps doctors learn more without adding extra medications.
Pavia, PaviaAges 18–90 - NCT07221188RecruitingPhase 3
Efimosfermin alfa for liver scarring in MASH
This study tests an investigational drug called efimosfermin alfa to see if it is safe and tolerable for people who have liver scarring (F2 or F3 stage) from a condition called MASH. The goal is to find out if the drug can help without causing serious side effects.
Arcadia, CaliforniaAges 18–75 - NCT07221227RecruitingPhase 3
Testing a new drug for MASH with moderate scarring
This trial tests a new medicine called Efimosfermin Alfa for people with MASH (a fatty liver disease) and moderate liver scarring. It aims to see if the medicine can improve the liver condition.
Chandler, ArizonaAges 18–75 - NCT07201649Recruiting
Liver disease and artery calcification study
This study looks at how liver function and scarring affect calcium buildup in arteries. It may help people waiting for a liver transplant understand these changes.
Nice, Alpes-maritimesAges 18 years+ - NCT07193862RecruitingEarly Phase 1
Testing a tiny device to find best treatments for liver tumors
This study tests a tiny device that is placed in your liver tumor during surgery. It checks how well different chemotherapy drugs work on your specific cancer, which may help your doctor choose the best treatment for you.
Lake Success, New YorkAges 18 years+ - NCT07198854Recruiting
Stem cell treatment for liver failure in hepatitis B patients
This trial looks at how well stem cell (MSC) treatment works for people with severe liver failure caused by hepatitis B. It checks what factors affect the success of the treatment.
Guangzhou, GuangdongAges 18 years+ - NCT07191561Recruiting
Liver fat and alcohol use disorder study
This trial looks at how the liver processes fat in people with alcohol use disorder. It may help find better ways to treat liver problems related to drinking.
Bethesda, MarylandAges 18–100 - NCT07191418Recruiting
Study of ERCP with RFA for pancreatic cancer with liver spread
This study tests a combination of endoscopic procedures (ERCP and RFA) to open the blocked bile duct and treat the tumor with heat in people with pancreatic cancer that has spread to the liver. The goal is to see if this approach can help relieve symptoms and improve outcomes while you continue chemotherapy.
UmeåAges 18–85
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,219 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.