Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05093881Recruiting
Follow-up study for people treated for alcoholic liver scarring
This study checks on people who previously received Cellgram-LC for alcohol-related liver cirrhosis (liver scarring) in an earlier trial. It helps researchers learn long-term safety and outcomes after that treatment.
Bucheon-siAges Any age - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05166499Recruiting
Amino acids to help rebuild muscle in liver cirrhosis
This trial tests whether a special amino-acid supplement can help reverse muscle loss in people with cirrhosis (scarring of the liver). It may help maintain or improve muscle strength and overall function, but eligibility depends on your liver status and overall health.
Cleveland, OhioAges 21–65 - NCT05178069RecruitingPhase 2
Probiotic supplement study for alcohol use disorder and liver injury
This Phase 2 trial studies whether a probiotic (LGG) can improve health in people with alcohol use disorder and alcohol-related liver injury. It’s not an alcohol treatment study, so participants are mainly joining to see how the supplement affects the body and liver-related outcomes.
Louisville, KentuckyAges 21–65 - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+ - NCT05185505RecruitingPhase 4
Atezolizumab and bevacizumab before liver transplant for liver cancer
This trial tests giving atezolizumab plus bevacizumab before liver transplant in people with hepatocellular carcinoma (HCC) that is too advanced to be listed within the “Milan criteria,” but still transplant-eligible. The goal is to control the cancer outside the transplant period and improve transplant outcomes.
Houston, TexasAges 18 years+ - NCT05187338RecruitingPhase 1/Phase 2
Study drugs that target immune checkpoints for solid tumors
This early-phase study tests a combination of three immune “checkpoint” medicines in people with advanced solid cancers. It aims to see how well they work and what side effects occur, including when given through a specific liver-focused treatment in eligible patients.
Guangzhou, GuangdongAges 18–70 - NCT05213598Recruiting
Biomarker study for liver disease after Fontan surgery
This study looks for blood and/or test markers that can better show how severe liver disease is in people who had the Fontan heart procedure. It also involves medical imaging and/or a liver biopsy or related procedures to help evaluate those markers.
Bethesda, MarylandAges 18–100 - NCT05215535Recruiting
Liver MRI before rectal cancer treatment
This trial tests whether doing an MRI scan of the liver before rectal cancer treatment helps doctors plan care better. You may be asked to have MRI before starting treatment and follow the study plan.
GothenburgAges 18 years+ - NCT05275608Recruiting
Low-carb diet effects in people with metabolic syndrome
This trial studies whether a very low-calorie, low-carb diet (VLCKD) can improve metabolic health in adults with metabolic syndrome, fatty liver, and type 2 diabetes. It may help lower blood sugar and improve related health markers if you fit their specific diabetes and liver/kidney criteria.
Novara, ItalyAges 25–65 - NCT05276037Recruiting
PET/CT scan to guide liver transplant decisions in liver cancer
This trial studies how a whole-body PET/CT scan using a “tracer” called 18F-FDG can help decide which people with liver cancer (HCC) may benefit from a liver transplant. It may help the transplant team better sort out who is likely to do well after transplant.
AntwerpAges 18–80 - NCT05321992Recruiting
Village health program to help prevent bile duct cancer
This trial tests whether a community-based behavior change program can lower the risk of cholangiocarcinoma, a bile duct cancer. If you live in one of the selected villages, you may be invited to participate and learn health-focused behavior changes.
Phu Wiang, Changwat Khon KaenAges 20 years+ - NCT05323201RecruitingPhase 1/Phase 2
B7H3 CAR-T therapy for advanced liver cancer
This trial tests an immune therapy made from your own blood cells (CAR-T) to treat advanced, unresectable liver cancer. It’s designed for people whose tumor has a specific marker called B7H3 and who meet blood, organ, and safety requirements.
Xuzhou, JiangsuAges 18–70 - NCT05331911RecruitingPhase 4
Propofol anesthesia vs sevoflurane for liver tumor surgery
This study compares two types of general anesthesia—propofol-based total intravenous anesthesia versus sevoflurane inhaled anesthesia—during planned surgery to remove liver tumors. The goal is to see whether the anesthesia choice affects long-term outcomes after partial liver removal for hepatocellular carcinoma.
Kaohsiung CityAges 20–80 - NCT05334836Recruiting
Scan for fat in the pancreas and link it to cyst features
This study uses scans to measure how common “fatty change” is in the pancreas. It then looks at whether fatty change is related to specific features of pancreatic cysts (and may also include healthy people).
Shatin, New TerritoriesAges 18 years+ - NCT05338294Recruiting
Tested surgery to help immune function in cirrhosis
This study looks at whether a type of keyhole spleen surgery plus cutting a large vein can improve immune function in people with cirrhosis. It may help reduce immune problems that can happen after complications like bleeding from varices (enlarged veins in the esophagus/stomach).
Yangzhou, JiangsuAges 18 years+ - NCT05346393Recruiting
TIPS procedure for kidney failure in people with cirrhosis
This trial studies whether a liver procedure called TIPS can help people with cirrhosis who develop sudden kidney failure (HRS-AKI). It aims to improve kidney function and overall outcomes, but participation depends on several safety checks.
AachenAges 18–80 - NCT05385237Recruiting
4D MRI scan to spot liver scarring
This study tests whether a special MRI scan (called 4D-MRI) can identify liver scarring or damage. It may help doctors measure liver fibrosis and inflammation without relying only on invasive tests.
Liestal, Basel-LandschaftAges 18 years+ - NCT05399745Recruiting
Study of biliary atresia in children with heart disease
This trial is studying children who have biliary atresia, a serious liver problem, including some who also have tetralogy of Fallot (a congenital heart condition). It also includes healthy children for comparison, and may help researchers understand the illness and treatments better.
CopenhagenAges birth–18 years - NCT05424003RecruitingPhase 2
Semaglutide to prevent weight gain after liver transplant
This trial tests semaglutide (a diabetes/weight-loss medicine) to help prevent weight gain after liver transplant. It is also looking at blood sugar and safety while you continue your transplant medicines.
Richmond, VirginiaAges 18–75 - NCT05428358Recruiting
MRI helps choose which pancreatic cancer patients can have surgery
This trial studies whether adding an MRI scan improves the selection of people with pancreatic cancer who may benefit from surgery. It focuses on patients without liver spread and with tumors that are borderline or likely removable.
AalborgAges 18–99 - NCT05430178Recruiting
Study of liver fat changes in kids with fatty liver disease
This study looks at how metabolism works in children and teens who have (or do not have) nonalcoholic fatty liver disease (NAFLD), a condition where fat builds up in the liver. Participants may include healthy-weight controls, obese controls without NAFLD, and kids with NAFLD who are already scheduled for a liver biopsy for clinical reasons.
Oklahoma City, OklahomaAges 10–20 - NCT05433467Recruiting
CT-guided locating for tiny liver cancer before surgery
This study tests a CT-guided method to find and precisely locate very small liver cancer spots before surgery. It may help surgeons remove the tumor more accurately when standard scans cannot clearly see it.
Yangzhou, JiangsuAges 18 years+ - NCT05444478Recruiting
Microwave ablation plus lenvatinib for recurrent liver cancer
This trial tests whether combining heat treatment to kill liver tumors (microwave ablation) with the medicine lenvatinib can better control recurrent hepatocellular carcinoma (HCC). It may help shrink tumors or slow growth for people whose cancer has come back but who have limited tumor burden.
Changsha, HunanAges 18–75
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.