Clinical trials
Lung cancer clinical trials
Cancer that begins in the lungs, often linked to smoking but also affecting non-smokers. We’re tracking 2,008 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06789172RecruitingPhase 1
New drug OKN4395 with or without pembrolizumab for solid tumors
This trial tests a new oral drug called OKN4395, which targets a COX2-related immune pathway, alone or with the immunotherapy pembrolizumab, in people with advanced solid tumors. It may be an option if you have certain types of cancer that have stopped responding to other treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT07718243RecruitingPhase 1/Phase 2
Combining two immunotherapies for solid tumors, melanoma, and lung cancer
This trial tests a new drug (bexmarilimab) plus nivolumab (an approved immunotherapy) for people with advanced solid tumors, melanoma, or non-small cell lung cancer (NSCLC) that has stopped responding to standard treatments.
ManchesterAges 18 years+ - NCT06198868Recruiting
MRD blood test to guide treatment in lung cancer
This trial uses a blood test (ctDNA and CTC) to check for minimal residual disease (MRD) after treatment for stage IIA-IIIC non-small cell lung cancer. The goal is to see if MRD can help predict whether the cancer will come back and guide decisions on extra treatment to prevent recurrence.
Nanjing, JiangsuAges 18 years+ - NCT05717803RecruitingPhase 3
Surgery choice for certain early lung cancers with glasslike nodules
This study compares a lung surgery approach (segmentectomy) for people with early, invasive lung cancer that shows “ground-glass” on scans. It aims to see if this less extensive surgery can treat the cancer effectively when the tumor is in a specific size and scan pattern range.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07833085Recruiting
Imaging test for solid tumors using a special tracer
This study tests a new imaging method that uses a special tracer to find solid tumors in the body. It may help doctors see tumors more clearly and guide treatment.
Wuhan, HubeiAges 18 years+ - NCT05902559Recruiting
Study of new lung-check biomarkers in older adults
This study looks at new blood or test “biomarkers” to understand how well targeted lung health checks work. You join if you’re already attending the NHS lung health check program and can consent.
LondonAges 55–74 - NCT07713732RecruitingPhase 1
Combination treatment for advanced solid tumors
This trial tests a new drug called TLN-499 combined with another drug (venetoclax) for people with certain advanced solid tumors that have not responded well to previous treatments. The goal is to see if the combination is safe and might help shrink tumors.
Camperdown, New South WalesAges 18 years+ - NCT07623473Recruiting
Blood test to help identify lung nodules as cancer or benign
This study tests whether a simple blood test can accurately identify whether a lung nodule (small spot) found on imaging is cancer or harmless. If it works, it could help doctors avoid unnecessary procedures and speed up diagnosis.
Gentofte MunicipalityAges Any age - NCT07629375Recruiting
Creating Research Models From Your Lung Cancer Tissue
This study collects lung cancer tissue samples from patients undergoing surgery to create laboratory models that help researchers test new treatments. Your participation helps advance personalized cancer medicine for future patients.
Rome, RomeAges 18 years+ - NCT07486219Recruiting
Lung MRI for staging tumors and nodes
This trial uses advanced lung MRI scans to get more detail on tumors and lymph nodes. It may help people with non-small cell lung cancer to get a clearer picture of their cancer stage without extra radiation.
PaviaAges 18 years+ - NCT07478809Recruiting
Long-term study of RATIONALE-307 trial participants
This study looks back at people who took part in the RATIONALE-307 trial for a type of lung cancer called squamous non-small cell lung cancer. It aims to learn more about their health outcomes over time by only including those who were still alive when the original trial ended.
BeijingAges Any age - NCT07435038RecruitingPhase 1/Phase 2
Trial of BPI-572270 for advanced solid tumors with RAS mutations
This trial tests a new drug, BPI-572270, for people with advanced solid tumors that have specific changes in the RAS gene. It may be an option if you have already tried standard treatments for your cancer type.
Blacktown, New South WalesAges 18 years+ - NCT06458894Recruiting
Home pre-surgery rehab for lung surgery patients
This trial tests a home-based pre-habilitation program using the internet for people who are 60 or older and planning lung surgery. The goal is to see if this approach helps patients prepare for surgery and recover better.
Yiwu, ZhejiangAges 60–99 - NCT07291973Recruiting
Microwave ablation for small lung tumors
This study tests a new microwave device that uses heat to destroy small lung tumors. It may be an option if your nodule is 20 mm or smaller and cannot be removed with surgery.
ParisAges 18 years+ - NCT03978377Recruiting
Checks heart and lung effects after chest radiation
This study looks at how chest radiation treatment affects the heart and lungs in people with certain lung or esophagus cancers. It may help doctors better predict and prevent these side effects during curative (aimed at cure) radiotherapy.
LeuvenAges 18 years+ - NCT07242547RecruitingPhase 2
Tarlatamab maintenance for limited-stage small cell lung cancer
This trial tests a new immunotherapy medicine called tarlatamab given as maintenance therapy after initial treatment for limited-stage small cell lung cancer. It aims to keep the cancer from coming back.
Albacete, AlbaceteAges 18 years+ - NCT06903117RecruitingPhase 1
CAR T-Cell Therapy for CEA-Positive Advanced Lung Cancer
This early-stage trial tests a special immune cell treatment (CAR T cells) designed to target and attack lung cancer cells that have a protein called CEA on their surface. It's for people with advanced lung cancer who have already tried at least two standard treatments without success.
ShanghaiAges 18 years+ - NCT07177937RecruitingPhase 1
Study of DXC014 for advanced solid tumors
This trial tests DXC014, a new drug, in people with advanced solid tumors, including prostate cancer. It aims to see if the drug is safe and effective.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07169994RecruitingPhase 1/Phase 2
Testing YL202 with other cancer treatments for advanced solid tumors
This trial is testing a new drug called YL202 in combination with other anti-cancer treatments for people with advanced solid tumors that have not responded to standard therapy. The goal is to see if this combination can shrink tumors or slow their growth.
Hefei, AnhuiAges 18–75 - NCT07060625Enrolling by invitation
Does a raised position help oxygen after lung surgery?
This study tests whether a slightly raised head-and-shoulders position (semi-recumbent) helps prevent low oxygen levels after lung surgery. If you are having a small-incision lung removal, it may help you breathe better after the operation.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06934499Recruiting
Tunisian lung cancer study for adults
This study looks at treatments and care for people living in Tunisia who have been diagnosed with lung cancer. It may help researchers learn more about options available for lung cancer patients.
AryanahAges 18 years+ - NCT06895031RecruitingPhase 2
JYP0015 for advanced solid tumors with RAS mutations
This trial tests a new drug called JYP0015 for people with advanced solid tumors that have a specific change in the RAS gene. It aims to see if the drug can help when other treatments have stopped working or caused too many side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT06848699RecruitingPhase 1/Phase 2
Testing HLX43 plus Serplulimab for advanced solid tumors
This trial tests a new combination of two cancer drugs (HLX43 and Serplulimab) for people with advanced solid tumors, especially those with a specific type of lung cancer (NSCLC) that has an EGFR mutation. The goal is to see if this combination can shrink tumors or slow their growth.
Hunan, ChangshaAges 18–75 - NCT06419179Enrolling by invitationPhase 2
Maintenance therapy for HRD-positive small-cell lung cancer
This trial tests whether a combination of two medications, durvalumab and olaparib, can help keep your extensive-stage small-cell lung cancer from coming back after standard first-line treatment. It is for people whose tumors have a specific genetic feature called HRD.
Cologne, North Rhine-WestphaliaAges 18–120
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Common questions
- Are there clinical trials for lung cancer?
- Yes. Clin2 currently lists 2,008 recruiting lung cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.