Clinical trials
Lung Transplantation clinical trials
Below are recruiting lung transplantation clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06960421Recruiting
Exercise program for people waiting for a lung transplant
This study tests a home-based exercise program to improve frailty in people waiting for a lung transplant. The program aims to help you become stronger and better prepared for surgery and recovery.
San Francisco, CaliforniaAges 18–75 - NCT04118660Recruiting
Thoracic specimen registry for adults with chest conditions
This study is a “specimen registry,” meaning it collects and stores samples from adults with chest (thoracic) diseases. It may help researchers better understand lung and chest conditions and improve future testing or treatments.
Rochester, MinnesotaAges 18 years+ - NCT06615492Recruiting
Lung transplant study: comparing two ECMO methods
This study compares two ways of using a heart-lung machine (ECMO) during lung transplant surgery. The goal is to see if using ECMO only when needed works as well as using it for everyone. This could help reduce risks and improve recovery.
Edmonton, AlbertaAges 18 years+ - NCT06082037RecruitingPhase 3
Testing belumosudil for chronic lung allograft dysfunction after transplant
This trial tests an oral medication called belumosudil for people with chronic lung allograft dysfunction (CLAD) after a double lung transplant. It may help slow the decline in lung function.
Birmingham, AlabamaAges 18 years+ - NCT03500731RecruitingPhase 1/Phase 2
Lung and bone marrow transplant for lung and blood failure
This Phase 1/2 study tests a special lung-and-bone-marrow transplant approach for people with severe lung disease and bone marrow failure (low blood counts). The goal is to see if the treatment is safe and whether it can improve outcomes when standard long-term immune-suppressing medicines are a poor fit.
Pittsburgh, PennsylvaniaAges 18–60 - NCT07192458RecruitingPhase 2
High vs. Standard Dose Flu Vaccine in Lung Transplant
This study compares a high-dose flu vaccine to the standard dose in lung transplant recipients. It aims to see if a higher dose gives better protection against the flu.
Nashville, TennesseeAges 18 years+ - NCT07017608Recruiting
Breathing effort before and after tube removal
This study measures how hard your breathing muscles work while you are on a ventilator and right after the breathing tube is removed. It may help doctors understand how to make the transition easier.
Toronto, OntarioAges 18 years+ - NCT07046910RecruitingPhase 2
MRI to detect lung rejection after transplant
This study uses a special MRI scan (called hyperpolarized gas MRI) to check for signs of lung rejection after a transplant. The goal is to see if the MRI can help detect rejection earlier and more safely than standard bronchoscopy alone.
Charlottesville, VirginiaAges 18–80 - NCT05837663Recruiting
Study using blood tests to better assess lung cancer
This study looks at whether a specialized blood test can help doctors better assess lung cancer. It may be helpful if you are an adult who can safely participate and provide a sample for testing.
Phoenix, ArizonaAges 18 years+ - NCT04782752Recruiting
Radiation before lung transplant to help stop lung cancer spread
This study tests a focused, low-dose type of radiation given before a lung transplant. The goal is to help your immune system recognize and attack cancer cells (called “radiovaccination”) and improve outcomes for people who cannot get curative treatment with surgery or SBRT alone.
Toronto, OntarioAges 18 years+ - NCT05689476Recruiting
Measuring diaphragm breathing signals during ICU ventilation
This study measures electrical activity of the diaphragm and how your breathing system works while you are on a breathing machine in the ICU. It may help doctors better understand breathing during recovery after major lung events.
Padova, ItalyAges 18 years+ - NCT06093867Recruiting
Tracking lung health after stem cell transplant
This study follows people getting a stem cell transplant to watch for lung problems, like infections or other lung diseases, that can happen after the transplant. The goal is to catch these issues early.
Bethesda, MarylandAges 5–70 - NCT07189377RecruitingPhase 4
Light, ex-vivo treatment and antivirals for lungs from hepatitis B donors
This trial tests a new way to safely use donor lungs that carry the hepatitis B virus (HBV). It combines a special light treatment, ex-vivo lung perfusion (cleaning the lungs outside the body), and antiviral medicines to prevent infection in the recipient. If you are on the lung transplant list and have been vaccinated against hepatitis B, this study may help expand your donor options.
Toronto, OntarioAges 18 years+ - NCT05502913RecruitingPhase 2
Fecal transplant plus cancer immunotherapy for lung cancer
This trial studies whether giving a fecal microbiota transplant (a stool-based sample from a carefully screened donor) alongside immune checkpoint inhibitors can improve outcomes in people with lung cancer. It aims to change the gut bacteria to help the immune system work better against the cancer.
BeershebaAges 18 years+ - NCT05724745Recruiting
3D lung breathing test during MRI versus standard spirometry
This study compares a new 3D MRI-based breathing test with the usual breathing test called spirometry. It may help doctors measure lung function more precisely in healthy people and in people with asthma, COPD, or after a double lung transplant.
Orsay, FranceAges 18–90 - NCT02423070Recruiting
Study how donor genetic material behaves after lung or heart transplant
This study looks at how transplanted genetic material (DNA) changes and settles in the body after lung or heart transplant. It may help doctors understand transplant healing and improve future care for transplant recipients and candidates.
Phoenix, ArizonaAges 14–80 - NCT05664204Recruiting
ECMO before or after lung transplant to improve outcomes
This study looks at using a heart–lung machine (ECMO) to reduce complications and deaths after a lung transplant. It focuses on people getting a lung transplant who have certain types of lung-vessel (pulmonary) pressure problems.
ParisAges 18 years+ - NCT07823010Enrolling by invitationPhase 1/Phase 2
Xenon gas MRI scan study for children
This study is developing a new type of MRI scan that uses xenon gas to take pictures of the lungs. It may help doctors see how well your lungs are working without any radiation.
Cincinnati, OhioAges Any age - NCT06112951Recruiting
ECP treatment for early signs of lung transplant rejection
This trial tests whether a therapy called extracorporeal photopheresis (ECP) can stop early, silent rejection in lung transplant patients. It is for people who have developed donor-specific antibodies but still have normal lung function.
ViennaAges 18 years+ - NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning
This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.
TorontoAges 18 years+ - NCT07281118Recruiting
Nerve freezing for pain after double lung transplant
This trial tests a procedure called intercostal cryoanalgesia, which freezes nerves in the chest to reduce pain after a double lung transplant. It may help you feel less pain and use fewer painkillers after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07280611Recruiting
Breathing reflex study in double lung transplant patients
This study looks at a natural breathing reflex (the Hering-Breuer reflex) in people who have had a double lung transplant and are on a ventilator in the ICU. It compares them with other ICU patients who are on a ventilator after non-chest surgery, to see how the reflex works after a lung transplant.
Milan, MichiganAges 18 years+ - NCT06538376Recruiting
New portable chest X-ray for ICU patients
This study tests a new portable chest X-ray that can be used in the ICU to check for problems like fluid in the lungs, trouble breathing, or swallowing issues. It is designed to help doctors see these problems more easily without moving you to the radiology department.
Boston, MassachusettsAges 18 years+ - NCT06422273Enrolling by invitationPhase 3
TXA vs Saline to Prevent Bleeding After Lung Transplant Biopsy
This trial tests whether a medication called tranexamic acid (TXA) can help prevent bleeding after a lung transplant biopsy. It compares TXA to a saltwater solution (saline) to see if it reduces the need for procedures to stop bleeding.
Grand Rapids, MichiganAges 18 years+
Hear when a new Lung Transplantation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for lung transplantation?
- Yes. Clin2 currently lists 95 recruiting lung transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.