Clinical trials
Lung Transplantation clinical trials
Below are recruiting lung transplantation clinical trials, each written for real people, not researchers. We’re tracking 98 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning
This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.
TorontoAges 18 years+ - NCT04439916Recruiting
Preventing CMV after lung transplant in special donor/recipient pairs
This study looks at how to prevent and monitor a virus called CMV after a lung transplant. It is for adults who are not carrying CMV themselves, but who receive lungs from donors who are CMV-positive, and it may help tailor safer follow-up care after transplant.
Edmonton, AlbertaAges 18 years+ - NCT06370832Recruiting
Breathing muscle training for people waiting for a lung transplant
This study tests if a special breathing exercise (inspiratory muscle training) can strengthen your breathing muscles while you wait for a lung transplant. You'd do the training alongside your regular pulmonary rehab sessions.
Edmonton, AlbertaAges 18 years+ - NCT06490744Recruiting
Lung function after COVID-19 in lung transplant patients
This study looks at how lung function changed over time in lung transplant patients who had a moderate to severe COVID-19 infection. It may help doctors understand how to better care for transplant patients after a serious COVID-19 illness.
StrasbourgAges 18 years+ - NCT06538376Recruiting
New portable chest X-ray for ICU patients
This study tests a new portable chest X-ray that can be used in the ICU to check for problems like fluid in the lungs, trouble breathing, or swallowing issues. It is designed to help doctors see these problems more easily without moving you to the radiology department.
Boston, MassachusettsAges 18 years+ - NCT07281118Recruiting
Nerve freezing for pain after double lung transplant
This trial tests a procedure called intercostal cryoanalgesia, which freezes nerves in the chest to reduce pain after a double lung transplant. It may help you feel less pain and use fewer painkillers after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT06998706RecruitingPhase 1
Testing patient's own lung stem cells for ILD
This study tests whether a patient's own lung stem cells can be used to repair damaged lungs in people with interstitial lung disease. It is an early-stage trial to see if the treatment is safe and may help improve breathing.
Qionghai, HainanAges 40–75 - NCT05025774Recruiting
Exercise program study for young heart, leukemia, and lung survivors
This study looks at how an exercise program affects fitness and lung function in young people who are survivors of certain conditions (heart transplant, leukemia, or lung disease from prematurity). The goal is to see whether exercise can improve breathing and overall physical function safely.
Minneapolis, MinnesotaAges 8–25 - NCT06403111RecruitingPhase 2
FMT with immunotherapy and chemotherapy for advanced lung cancer
This trial tests a combination of fecal microbiota transplantation (FMT), immunotherapy, and chemotherapy as a first treatment for advanced non-small cell lung cancer that does not have a driver gene mutation. The goal is to see if adding FMT can help the immune system fight the cancer better.
ChangzhouAges 18–80 - NCT01852370Enrolling by invitationPhase 1/Phase 2
Lung and bone marrow transplant plan for immune system disorders
This early-phase study tests a step-by-step transplant approach: first replacing the lungs, then doing a bone marrow (stem cell) transplant to treat certain immune deficiency diseases. It may help people whose immune problem has led to severe, end-stage lung disease.
Pittsburgh, PennsylvaniaAges 5–45 - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+ - NCT05215327RecruitingPhase 2
Higher-dose flu vaccine vs standard dose after lung transplant
This trial tests whether a higher dose of flu vaccine works better than the standard dose for people who have had a lung transplant. It may help improve protection against seasonal flu while monitoring safety.
Nashville, TennesseeAges 16 years+ - NCT05851755Enrolling by invitation
Italian lung cancer study observing care and outcomes
This is an observational study of people with lung cancer. The goal is to better understand care patterns and outcomes; joining would involve giving consent and answering study questions.
L’AquilaAges 18 years+ - NCT05669846RecruitingPhase 2
FMT plus pembrolizumab for advanced lung cancer after prior treatment
This Phase 2 trial studies whether adding fecal microbiome transplant (FMT) to pembrolizumab can help people with advanced, PD-L1–positive non-small cell lung cancer that has returned or progressed after anti–PD-1/PD-L1 therapy. You may be asked to give new tumor tissue and undergo gut procedures, because the study aims to change gut bacteria to boost the immune response.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03819296RecruitingPhase 1
Fecal transplant to treat cancer immunotherapy bowel side effects
This early-phase study tests whether changing your gut bacteria with a fecal transplant can improve diarrhea or colitis caused by cancer immunotherapy. It may help people whose symptoms have not fully settled with standard treatments like steroids and other immune-blocking medicines.
Houston, TexasAges 18 years+ - NCT04038619RecruitingPhase 1
Fecal transplant for immune-therapy diarrhea or bowel inflammation
This early-phase study tests whether stool/fecal microbiota transplant (a fecal transplant) can help people who develop significant diarrhea or colitis after immune-checkpoint therapy. It aims to reduce bowel inflammation and improve symptoms, while carefully checking for infections.
Houston, TexasAges 18 years+ - NCT03630211RecruitingPhase 2
Study of stem cell transplant for systemic sclerosis in youth
This Phase 2 study tests whether an “autologous” stem cell transplant—using your own stem cells—can reduce systemic sclerosis disease activity. It is mainly for children, teens, and young adults whose disease did not improve despite standard medicines.
Pittsburgh, PennsylvaniaAges 8–60 - NCT04098445Recruiting
Study of lung injury in children after stem cell transplant
This study follows children and teens who get a stem cell transplant to learn how lung problems develop over time. Your participation could help doctors better predict, prevent, and manage lung injury after transplant.
San Francisco, CaliforniaAges Up to 24 years - NCT00106925Recruiting
Long-term follow-up for people after stem cell transplant
This study follows people who are at least 3 years out from their first stem cell transplant to learn how they are doing long term. It may help improve future transplant care by tracking outcomes over time.
Bethesda, MarylandAges 7–80 - NCT06946953RecruitingPhase 1/Phase 2
Stem cell transplant for COPD: a safety and early efficacy study
This trial tests whether transplanting a patient's own lung stem cells can improve lung function in people with chronic obstructive pulmonary disease (COPD). It aims to see if this treatment is safe and helps repair damaged lung tissue.
Qionghai, HainanAges 40–80 - NCT00001529Recruiting
Bone marrow cell selection method study for transplants
This study tests improved ways to select and collect bone marrow cells from healthy donors for use in transplants. Researchers are looking for healthy volunteers to donate cells that may help people who need bone marrow transplants.
Bethesda, MarylandAges 18–60 - NCT04008368RecruitingPhase 1/Phase 2
Second stem cell transplant for sickle cell with declining donor cells
This Phase 1/2 study tests whether repeating a stem cell transplant can help people with sickle cell disease (SCD) whose donor cells are no longer holding strong. It may help restore healthier blood cell production and reduce symptoms such as pain crises and severe anemia.
Bethesda, MarylandAges 2–80 - NCT03173937RecruitingPhase 1/Phase 2
Cord blood transplant for severe aplastic anemia or MDS
This trial tests a special type of cord blood transplant using lab-grown stem cells to help the new blood-forming cells “take” sooner. It’s for people with severe aplastic anemia or certain MDS cases who have not responded well to standard immune-suppressing treatments.
Bethesda, MarylandAges 4–75 - NCT07599176RecruitingPhase 1/Phase 2
Partial stem cell transplant for sickle cell disease from matched donors
This study tests a partial stem cell transplant from a matched donor to treat sickle cell disease. It may help reduce complications like strokes, organ damage, or pain crises.
Bethesda, MarylandAges 4–65
Hear when a new Lung Transplantation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for lung transplantation?
- Yes. Clin2 currently lists 98 recruiting lung transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.