Clinical trials
Lung clinical trials
Below are recruiting lung clinical trials, each written for real people, not researchers. We’re tracking 2,828 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06580002RecruitingPhase 2
Can Riluzole Help with Chemo Brain? A Pilot Study
This study tests if a medicine called riluzole (currently used for ALS) can help with 'chemo brain' – memory and thinking problems after cancer treatment. It is for people who feel their mental sharpness has declined after breast cancer therapy, certain chemotherapies, or brain radiation.
Orange, CaliforniaAges 18 years+ - NCT06552767Recruiting
Thrombosis and blood vessel inflammation study
This trial aims to learn more about blood clots, inflammation, and blood vessel problems. It may help researchers better understand these conditions and how they affect people.
Bethesda, MarylandAges 5–100 - NCT06561685RecruitingPhase 1
Study of LY4050784 for Advanced Solid Tumors with SMARCA4 Changes
This trial tests a new drug, LY4050784, for people with advanced solid tumors that have a specific change in a gene called SMARCA4 (BRG1). The study aims to see if the drug is safe and effective. It may be an option for those who have tried other treatments or have no standard options left.
Santa Monica, CaliforniaAges 18 years+ - NCT06567015RecruitingPhase 1/Phase 2
Study of a new drug for advanced lung cancer that stopped responding to current treatments
This trial tests a new medicine, STX-241, for people with a specific type of advanced lung cancer (NSCLC) that has stopped responding to current targeted therapies. The goal is to see if this new drug can help shrink or control the cancer.
Nashville, TennesseeAges 18 years+ - NCT06563388RecruitingPhase 3
SABR for limited metastatic cancer (ID-COMET trial)
This study tests a precise radiation technique called SABR to treat cancer that has spread to a few spots. It aims to see if this approach can help control the cancer better than usual treatment, especially for lung, prostate, colorectal, or other solid tumors with limited spread.
Buffalo, New YorkAges 1 year+ - NCT06555757Recruiting
Using AI and sound to predict heart failure worsening
This trial uses a smartphone app to record sounds from your chest and breathing. An AI system will analyze these sound patterns to predict when heart failure symptoms might get worse, so you can get help sooner.
Cambridge, CambridgeshireAges 18 years+ - NCT06554613RecruitingPhase 2
Olanzapine with first-line immunotherapy for advanced lung cancer trial
This trial tests whether adding the drug olanzapine to standard first-line immunotherapy (with or without chemotherapy) can help people with advanced lung cancer that does not have an EGFR mutation. It aims to improve treatment outcomes and quality of life.
Nanchang, JiangxiAges 18–75 - NCT06554353Recruiting
Breathing and exercise tests for shortness of breath
This study looks at how well two breathing tests work for people who have shortness of breath. You will do a breathing test and an exercise test to help doctors better understand your symptoms.
Rochester, New YorkAges 18 years+ - NCT06555588Recruiting
Supportive talk therapy for advanced cancer symptoms
This study tests a supportive talk therapy program (called Engage) delivered via video calls. It aims to help people with advanced cancer manage tough symptoms like pain, fatigue, and distress and improve daily functioning.
Durham, North CarolinaAges 18 years+ - NCT06563999RecruitingPhase 2
Study of new drugs for stage III lung cancer with rare gene changes
This trial tests whether giving treatment before surgery (neoadjuvant therapy) can help people with stage III lung cancer that has certain rare gene changes. The goal is to see if this approach can shrink the tumor enough to allow surgery.
Guangzhou, GuangdongAges 18–75 - NCT05227547Recruiting
Study of lung cell changes in smokers and lung disease
This study looks at specific lung cells (called alveolar cells) to understand how smoking and chronic lung disease may change them. You may be invited if you are having lung surgery and can safely take part.
CréteilAges 18 years+ - NCT06276530Recruiting
Lung surgery: large incision vs. robotic approach and breathing
This study compares how different types of lung surgery (a large incision vs. robotic-assisted small cuts) affect your posture and breathing. It aims to help doctors choose the best approach for recovery.
ParisAges 18 years+ - NCT06545331RecruitingPhase 1
A study of XB010 for advanced solid tumors
This trial tests an investigational drug called XB010 for people with solid tumors that have spread or cannot be removed by surgery. It aims to see if XB010 is safe and effective for several cancer types, including lung, breast, head and neck, and esophageal cancers.
Irvine, CaliforniaAges 18 years+ - NCT06538376Recruiting
New portable chest X-ray for ICU patients
This study tests a new portable chest X-ray that can be used in the ICU to check for problems like fluid in the lungs, trouble breathing, or swallowing issues. It is designed to help doctors see these problems more easily without moving you to the radiology department.
Boston, MassachusettsAges 18 years+ - NCT06533371Recruiting
Ultrasound for emphysema in COPD and lung cancer
This study uses ultrasound (a safe, painless sound wave test) to check for emphysema (damaged air sacs in the lungs) in people with COPD or those being screened for lung cancer. It aims to see if ultrasound can replace the need for CT scans.
Acquaviva delle FontiAges 18 years+ - NCT06536868RecruitingPhase 2
Tislelizumab with chemo and radiation for extensive-stage small cell lung cancer
This trial tests a combination of an immunotherapy drug (tislelizumab) with chemotherapy and chest radiation for people with extensive-stage small cell lung cancer (SCLC) that has spread. The goal is to see if this combination helps shrink or control the cancer longer.
Jincheng, ShanxiAges 18–80 - NCT06545747RecruitingPhase 3
MRI-guided radiation for advanced lung cancer
This trial tests a new way of giving radiation therapy for advanced lung cancer that cannot be surgically removed. It uses MRI scans to guide and adjust the radiation dose, which may help target the tumor more precisely and reduce side effects.
GuangzhouAges 18–75 - NCT06521502Recruiting
Studying inflammation in the heart and lungs in the ICU
This study collects blood samples from people in the ICU with sudden heart or lung problems caused by inflammation. The goal is to learn more about these conditions and improve future treatments.
Fresno, CaliforniaAges 18 years+ - NCT06529822RecruitingPhase 1
Personalized cancer vaccine for solid tumors with residual disease
This trial tests a personalized cancer vaccine designed to help your immune system fight any remaining cancer cells after surgery. It is for people with certain solid tumors—like bladder, stomach, melanoma, or lung cancer—that show signs of disease through a blood test.
Orlando, FloridaAges 18 years+ - NCT06516198Recruiting
Ear acupressure before lung surgery
This study tests whether ear acupressure can help people get stronger before major lung surgery. You'll wear small seeds on your ears and do exercise prehabilitation.
Chicago, IllinoisAges 50 years+ - NCT06526598Recruiting
Breathing support tailored to your effort in the ICU
This trial tests a new way of adjusting breathing machine support based on how hard you are breathing. It may help people with low oxygen levels who need a ventilator.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06515990RecruitingPhase 1/Phase 2
DM005 for Advanced Solid Tumors
This study tests a new drug called DM005 for people with advanced solid tumors (like lung, stomach, colon, liver, pancreas, or head and neck cancer) that have not responded to or can't tolerate standard treatments. The goal is to see if DM005 is safe and how well it works.
Detroit, MichiganAges 18 years+ - NCT06518655Recruiting
Can a breath test tell if a lung nodule is cancer?
This trial is testing a simple breath test to see if it can tell whether a lung nodule is cancer or not. If you have a lung nodule that will be removed by surgery, you may be able to help find out if breathing into a device can replace more invasive tests.
Beijing, Beijing MunicipalityAges 18–80 - NCT05903430Recruiting
MRI-guided focused radiation for limited spread cancer
This feasibility study tests whether MRI-guided, highly focused radiation can be safely delivered to tumors in the abdomen or central lung. It may help patients with a small number of metastases by aiming treatment more precisely and gathering detailed outcomes for future care.
Manchester, United KingdomAges 18 years+
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Common questions
- Are there clinical trials for lung?
- Yes. Clin2 currently lists 2,828 recruiting lung studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.