Clinical trials
Lung clinical trials
Below are recruiting lung clinical trials, each written for real people, not researchers. We’re tracking 2,908 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05188092Recruiting
Lung ultrasound to guide fluid removal in ICU patients
This trial tests whether using a quick scan of the lungs (lung ultrasound) helps ICU teams safely remove the right amount of extra body fluid. It aims to improve care for people who have just been put on a breathing machine but are expected to need it longer than a day.
Arnhem, GelderlandAges 18 years+ - NCT04712877Recruiting
Blood and tumor testing to choose the right lung cancer treatment
This trial tests tumor tissue and a blood sample to help doctors pick the most personalized treatment for people with suspected lung cancer. It may help ensure you get therapy matched to your specific tumor characteristics, especially when the cancer might be surgically removed.
Davis, CaliforniaAges Any age - NCT04992780RecruitingPhase 2
Hypo-fractionated radiation versus standard radiation for lung cancer
This study compares two different radiation schedules for stage III non-small cell lung cancer, both combined with chemotherapy and immunotherapy. It aims to see whether giving radiation in a different way can work as well (or better) and be safe while treating the cancer.
Kansas City, KansasAges 18 years+ - NCT05139719RecruitingPhase 2
HEC585 trial for slowing lung scarring decline
This Phase 2 study tests whether HEC585 can slow the decline in lung function in people with progressive fibrosing interstitial lung disease (PF-ILD). It may help preserve breathing capacity and breathing tolerance over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04893785RecruitingPhase 2
Cabozantinib plus temozolomide for advanced neuroendocrine lung tumors
This Phase 2 study tests whether combining cabozantinib with temozolomide can control advanced lung or gastrointestinal neuroendocrine tumors that have grown after prior treatments. It also closely monitors safety, including blood counts, organ function, and other side effects.
Naples, CampaniaAges 18 years+ - NCT05222087RecruitingPhase 1
Radiation for newly diagnosed metastatic lung cancer without driver mutations
This early study tests whether a specific kind of radiation can be safely given to people with newly diagnosed metastatic lung cancer when cure isn’t possible. It’s meant to see how well the treatment can be delivered and how it affects outcomes in a specific genetic group of tumors.
Southport, QueenslandAges 18 years+ - NCT04829708RecruitingPhase 3
Preventing brain spread in limited-stage small cell lung cancer
This trial compares two ways to manage limited-stage small cell lung cancer that has improved after initial chemotherapy and radiation. Participants will either get preventive brain radiation or have regular brain MRI scans instead, to see which approach is safer and works better.
Jinan, ShandongAges 18–75 - NCT04696575RecruitingPhase 2
Lamivudine added to chemoimmunotherapy for extensive-stage lung cancer
This trial tests whether adding lamivudine to standard chemoimmunotherapy can improve outcomes for people with extensive-stage small cell lung cancer. It aims to see if this combination controls the cancer better than standard treatment alone.
Buffalo, New YorkAges 18 years+ - NCT04469842RecruitingEarly Phase 1
Long-acting tacrolimus after lung transplant
This early-stage study tests a long-acting form of tacrolimus (a common anti-rejection medicine) soon after lung transplant. It aims to see if it can be used safely and effectively for people receiving lung transplants at Vanderbilt (VUMC).
Nashville, TennesseeAges 18 years+ - NCT03431064Recruiting
Ultrasound test during surgery to predict fluid needs in children
This study looks at a specific breathing maneuver done while your child is on a ventilator during surgery, and uses ultrasound-related measurements to predict whether they’ll need extra fluids. If it works, it may help doctors give the right amount of fluid and avoid problems from too little or too much.
Boston, MassachusettsAges Up to 17 years - NCT05504278RecruitingPhase 1
Testing IBI351 with chemotherapy for KRAS G12C lung cancer
This Phase 1 study tests whether IBI351, a targeted medicine, can be safely given with standard chemotherapy to treat advanced lung cancer that has a KRAS G12C mutation. It’s mainly looking at safety and early signs of effectiveness, and may offer a new option if your cancer matches these features.
Jilin City, ChangchunAges 18–75 - NCT05193240Recruiting
Swallowing test to predict vocal cord paralysis after lung surgery
This study checks whether a simple swallowing test can forecast vocal cord paralysis after lung surgery, compared with a camera exam of the throat. If predictions are accurate, it may help doctors prevent or plan treatment for swallowing and voice problems.
RouenAges 18 years+ - NCT05458934Recruiting
Breath test study for adults with lung or airway conditions
This study analyzes breath samples from adults with lung or airway problems. It may help researchers understand these conditions better by looking at what’s in your exhaled breath.
Zurich, Canton of ZurichAges 18 years+ - NCT04402788RecruitingPhase 2/Phase 3
Radiation added to immune therapy for extensive small cell lung cancer
This trial tests whether adding radiation therapy to standard immune therapy (atezolizumab) after initial chemo can help people with extensive-stage small cell lung cancer live longer and control the cancer better. You must have a good response (partial response) or stable disease after initial treatment, plus several lab/imaging checks to confirm safety.
Birmingham, AlabamaAges 18 years+ - NCT06945523RecruitingPhase 1
CAR-T cell therapy for CEA-positive advanced lung cancer
This trial tests a treatment using your own immune cells, modified to target a protein called CEA on lung cancer cells. It's for people with advanced lung cancer that has gotten worse after at least one prior treatment.
Wuhan, HubeiAges 18 years+ - NCT03546829RecruitingPhase 1
Testing targeted radiation plus short anti-microbial treatment
This early safety study tests a combination of focused radiation and a targeted anti-microbial (antibiotic/antifungal/antiviral/anti-parasite) plan for certain lung cancer that is starting to progress in a few spots. It aims to see whether this approach is safe and helps control the small areas of progressing cancer after prior treatment.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05341492RecruitingEarly Phase 1
CAR-T therapy for EGFR/B7H3-positive lung and triple-negative breast cancer
This early-phase trial tests CAR-T cells designed to find and attack tumors that show EGFR or B7H3 markers. It may help people with advanced lung cancer or triple-negative breast cancer after standard treatments.
Guangzhou, GuangdongAges 18–75 - NCT07178470Recruiting
Checking fluid status in home dialysis patients
This study looks at better ways to check for fluid overload in people doing dialysis at home. Your doctor will use a simple breathing scale, a physical exam, and a small bedside ultrasound to see which method matches your actual fluid status.
Indianapolis, IndianaAges Any age - NCT06169956Recruiting
Study of nivolumab with chemo before lung cancer surgery
This study looks at how well the immunotherapy drug nivolumab (Opdivo) works when given with standard chemotherapy before surgery for people with a certain type of lung cancer that has not spread. It may help shrink the tumor before surgery.
Kempten (Allgäu), BavariaAges 18 years+ - NCT06498141Recruiting
Gene study for interstitial lung disease
This study looks at a gene and telomere length in people with interstitial lung disease (a group of lung conditions that cause scarring). It aims to understand if certain genetic factors are linked to the disease. It may help if you have ILD and are otherwise healthy.
SohagAges 18 years+ - NCT06156943Recruiting
Fluid monitoring during lung surgery for high-risk patients
This study tests a new way to monitor your body's fluid levels during lung surgery, especially for patients who are at higher risk for complications. The goal is to improve recovery and reduce problems after surgery.
BronAges 18–80 - NCT05416775RecruitingPhase 1/Phase 2
Test drug SHR-8068 for advanced lung cancer
This trial tests SHR-8068 in people with advanced non-small cell lung cancer (NSCLC). It may help by controlling cancer after standard treatments have not worked, and it’s designed to find the right way to give the drug.
Hefei, AnhuiAges 18–75 - NCT06378892RecruitingPhase 2
Study of chemo plus lorlatinib for ALK+ lung cancer
This trial tests combining chemotherapy with lorlatinib for people with ALK-positive lung cancer that has spread outside the brain while on lorlatinib. The goal is to see if adding chemo can help control the cancer when it starts growing again.
AvianoAges 18 years+ - NCT07631624Recruiting
Blood test for lung cancer screening in smokers and former smokers
This study tests whether a simple blood test that detects smoking-related changes in DNA can help identify who should get lung cancer screening. Researchers want to see if this test is better at finding people at risk than current methods.
Antwerp, AntwerpenAges 50 years+
Hear when a new Lung trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for lung?
- Yes. Clin2 currently lists 2,908 recruiting lung studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lung trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lung trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.