Clinical trials
Malignancy clinical trials
Below are recruiting malignancy clinical trials, each written for real people, not researchers. We’re tracking 1,583 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06525740RecruitingPhase 4
Comparing two pain medicines for gynecologic cancer surgery
This trial compares two different pain medicines (methadone given by mouth or IV vs. hydromorphone given through a spinal injection) after surgery for gynecologic cancer. It aims to find which option provides better pain relief with fewer side effects.
Rochester, MinnesotaAges Any age - NCT06565260Recruiting
Exercise and nutrition program for cancer survivors and caregivers
This study offers a community-based program of exercise and nutrition classes for cancer survivors and their caregivers. It aims to help improve health and well-being after cancer treatment.
Buffalo, New YorkAges 18 years+ - NCT06541158Recruiting
Help with transportation for cancer treatment
This study tests a tool to help patients with solid tumors who are getting radiation therapy overcome transportation problems. If you have trouble getting to appointments, this could help you find ways to get there more easily.
Atlanta, GeorgiaAges 18 years+ - NCT06562777Recruiting
How symptoms differ between men and women during immunotherapy
This study looks at how symptoms during immunotherapy (a cancer treatment that boosts your immune system) may differ between men and women. Researchers will follow people with cancer who are starting immunotherapy to see if men and women report different side effects.
Portland, OregonAges 18 years+ - NCT06535867Recruiting
Comparing phone-based vs. in-person mouth cancer screening in rural India
This study compares two ways to find early signs of mouth cancer or conditions that could lead to cancer. One method uses a simple phone-based health check, and the other uses standard in-person screening. People in rural areas of Varanasi who are at risk—such as those who use tobacco or have mouth sores—may be able to join.
New York, New YorkAges 18 years+ - NCT06464055RecruitingPhase 1/Phase 2
A study of GQ1010 for advanced solid tumors
This trial tests a new drug called GQ1010 for people with advanced solid tumors that have stopped responding to standard treatments. The drug targets a protein called Trop-2 on cancer cells to try to shrink tumors or slow their growth.
BeijingAges 18 years+ - NCT06438588Recruiting
Fasting-mimicking diet to reduce immunotherapy side effects
This trial tests whether a special low-calorie 'fasting-mimicking' diet can reduce side effects from common immunotherapy drugs for advanced cancer. If you're on a PD-1, PD-L1, or CTLA-4 inhibitor, this diet might help you feel better during treatment.
Jacksonville, FloridaAges 18 years+ - NCT06470971RecruitingPhase 2
Siltuximab to prevent severe side effects during immunotherapy rechallenge
This trial tests if siltuximab can prevent severe immune-related side effects when patients restart immunotherapy (anti-PD-1/PD-L1) after previous severe side effects. It aims to make rechallenge safer for people with advanced cancer.
Columbus, OhioAges 18 years+ - NCT06201078RecruitingPhase 2
Second radiation for prostate cancer that returns locally
This trial tests a second round of precise, high-dose radiation (stereotactic body radiotherapy) for men whose prostate cancer has come back only in the prostate after their first radiation treatment. It aims to control the recurrence with fewer side effects.
GliwiceAges 18–80 - NCT06053333Recruiting
Social factors in liver, bile duct, and gallbladder cancer
This study looks at how social and economic factors (like income, housing, and support) affect people with liver, bile duct, or gallbladder cancer. The goal is to learn more about these factors to improve care and outcomes.
Rochester, MinnesotaAges 18 years+ - NCT06026605RecruitingEarly Phase 1
Study of WTX212A for advanced solid tumors
This trial tests a new drug called WTX212A for people with advanced solid tumors that are no longer responding to standard treatments. The goal is to find the best dose and see if the drug is safe and effective.
Hangzhou, ZhejiangAges 18–75 - NCT06022965Recruiting
Telemedicine support for older adults with cancer
This study uses telemedicine (video or phone visits) to help older adults with cancer, especially those in underserved communities, get better care. If you're 65 or older and starting a new cancer treatment, you may be able to join from home in English, Spanish, or Chinese.
Duarte, CaliforniaAges 65 years+ - NCT05819684RecruitingPhase 1
First testing of SHR-4602 for HER2-positive solid tumors
This Phase 1 study tests a new medicine called SHR-4602 in people with advanced solid tumors that have HER2 changes. It is for cases where standard treatments have not worked, cannot be tolerated, or are not available.
Guangzhou, GuangdongAges 18–75 - NCT05718726Recruiting
Study of infections after spleen removal surgery
This trial looks at what happens after surgery to remove the spleen in people who also have major cancer surgery through the belly. It may help reduce or better manage serious infections after this kind of operation.
Basingstoke, HampshireAges 18–79 - NCT05411523Recruiting
Spinal cord stimulation study for long-term chemotherapy nerve pain
This trial tests whether spinal cord stimulation can reduce pain and improve quality of life in people with long-lasting nerve pain from chemotherapy (CIPN). You must already have tried at least two nerve-pain medicines and still have significant pain, and you must have had a successful spinal cord stimulator test before joining.
Rochester, MinnesotaAges 18 years+ - NCT05642611RecruitingPhase 3
Cooling and compression for nerve protection during chemotherapy
This study tests whether using cooling and/or compression on the arms or legs can prevent nerve damage that can happen from certain chemotherapy drugs. If you get eligible chemo soon, this may help lower the chance of painful numbness or tingling during treatment.
Birmingham, AlabamaAges 18 years+ - NCT05584449Recruiting
After-cancer group program for young adult survivorship goals
This trial offers a structured group curriculum to help young adults after cancer treatment manage survivorship concerns and improve outcomes. You may be eligible if you finished curative cancer treatment recently and can fully join all six group meetings.
Scottsdale, ArizonaAges 18–39 - NCT05286138Recruiting
Cancer outcomes in people with blood disorders like thalassemia or sickle cell
This study looks at how cancers occur and what they look like in people with certain inherited blood disorders, such as beta-thalassemia, hemoglobin H disease, and sickle cell disease. It may help doctors better understand cancer patterns in these conditions so care can be improved.
CagliariAges 18–100 - NCT05443425RecruitingPhase 1
Leflunomide plus steroids for acute graft-versus-host disease
This early-phase trial tests whether adding leflunomide to standard steroid treatment can better control acute graft-versus-host disease (aGvHD) after a stem cell transplant. It may help reduce the immune reaction that damages the body while keeping treatment safe and manageable.
Duarte, CaliforniaAges 18 years+ - NCT05608148RecruitingPhase 1
GAIA-102 for relapsed or hard-to-treat childhood cancers
This Phase 1 study tests GAIA-102 in children and young adults whose cancer has returned or not responded to standard treatments. It aims to see if the treatment is safe and whether it may shrink tumors in certain pediatric solid cancers.
Fukuoka, FukuokaAges 1–24 - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT05170958RecruitingPhase 1/Phase 2
Study of LBL-024 for advanced cancers
This trial tests LBL-024 in people with advanced cancer to see how it works and how safe it is. You may consider it if you are well enough for study visits and have time to complete at least about 12 weeks of follow-up.
Hefei, AnhuiAges 18–80 - NCT04731610Recruiting
Radiation after thymoma surgery versus watchful waiting
This trial compares two approaches after complete surgical removal of stage IIb or III thymoma: targeted radiation (conformal post-operative radiotherapy) or no further treatment right away (surveillance). It aims to see whether adding radiation lowers the risk of the cancer coming back without causing unacceptable side effects.
CaenAges 18–75 - NCT04797039Recruiting
MRI-guided freezing treatment for localized prostate cancer
This trial studies a treatment where doctors use MRI pictures to guide freezing of a prostate tumor. It may help men with smaller, well-placed prostate cancers who cannot or do not want surgery or radiation right now.
Rochester, MinnesotaAges 30–100
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Common questions
- Are there clinical trials for malignancy?
- Yes. Clin2 currently lists 1,583 recruiting malignancy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malignancy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malignancy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.