Clinical trials
Malignancy clinical trials
Below are recruiting malignancy clinical trials, each written for real people, not researchers. We’re tracking 1,543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07708987RecruitingPhase 2
Withaferin-A for steroid-resistant graft-versus-host disease
This trial tests a plant-based medicine, Withaferin-A, in people whose graft-versus-host disease (GVHD) after a stem cell transplant has not responded to steroid treatment. GVHD is a condition where donated immune cells attack the body; this study aims to see if Withaferin-A can help control it.
Navi Mumbai, MaharashtraAges 12–65 - NCT07700758RecruitingPhase 2
Belzutifan for teenagers with solid tumors
This study tests an oral drug called belzutifan in teenagers with certain solid tumors. Belzutifan may shrink tumors by blocking a protein that helps them grow.
Iowa City, IowaAges 12–17 - NCT07700160RecruitingPhase 1/Phase 2
Testing a new drug for advanced solid tumors
This trial tests an experimental drug called VBC108 in people with advanced solid tumors that have not responded to other treatments. The study aims to see if the drug is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT07705035RecruitingPhase 1
DBC-664 for adults with advanced solid tumors
This trial tests a new drug called DBC-664 for people with solid tumors that have come back or spread and cannot be removed by surgery. It may be an option if you have tried other treatments or if standard options are limited.
Denver, ColoradoAges 18 years+ - NCT07697937RecruitingPhase 2
YH02 injection for advanced solid tumors that didn't respond to treatment
This trial tests a new injection, YH02, directly into tumors for people with advanced solid tumors (like head and neck, breast, or melanoma) that are no longer responding to standard treatments. The goal is to see if it can shrink tumors or slow disease progression.
TianjinAges 18 years+ - NCT07695389Recruiting
Study of a new wound dressing after skin cancer surgery
This study tests a special dressing (called CAMP) for healing wounds after skin cancer removal. The dressing is applied along with your usual care, and we compare it to usual care alone to see which helps wounds heal better.
Tulsa, OklahomaAges 18 years+ - NCT07682883Enrolling by invitation
Mouth screening to prevent oral cancer
This study checks how well routine mouth exams can find early signs of oral cancer. It is for adults who do not already have a condition called OPMD (a mouth problem that can lead to cancer) and are not being treated for it.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07682870RecruitingPhase 1/Phase 2
Study of VG2025 for advanced solid tumors
This trial tests a new drug, VG2025, given through a vein for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and if it can help shrink or control the tumors.
ShanghaiAges 18–75 - NCT07680257RecruitingEarly Phase 1
CLDN18.2 CAR T cells for advanced solid tumors
This trial tests a new treatment called CLDN18.2 CAR T cells in people with advanced solid tumors that have a specific marker (CLDN18.2). It aims to see if it is safe and works against cancers that have not responded to standard treatments.
Hefei, AnhuiAges 18–75 - NCT06666790Recruiting
DermaSensor device study for suspicious skin spots
This study is testing a handheld device that scans skin lesions to help detect melanoma. If you have a spot that your doctor thinks could be melanoma, this study will see how well the device works compared to standard checks.
New Smyrna Beach, FloridaAges 40 years+ - NCT07673614Recruiting
Gentle brain stimulation for nerve pain from chemotherapy
This study tests a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) to see if it can reduce nerve pain, numbness, or tingling caused by chemotherapy. If you've finished cancer treatment but still have these symptoms, this may help improve your quality of life.
Ann Arbor, MichiganAges 18–85 - NCT07680205RecruitingPhase 2
Study of Belzutifan for Pheochromocytoma or Paraganglioma
This trial tests a drug called belzutifan to see how it affects hormone levels in people with rare adrenal tumors (pheochromocytoma or paraganglioma). It may help control symptoms caused by excess hormones.
Cambridge, CambridgeshireAges Any age - NCT07671937Recruiting
Sharing patient feedback in cancer care team meetings
This study gathers your feedback (like symptoms and quality of life) and shares it with your cancer care team during their group meetings, so they can better tailor your care. It is for people recently diagnosed with pancreatic, breast, or gynecologic cancer and aims to make sure your voice is heard in treatment decisions.
Birmingham, AlabamaAges 18 years+ - NCT06640582RecruitingPhase 1/Phase 2
TIL therapy with pembrolizumab for advanced brain cancer
This trial tests a new treatment for advanced brain cancers like glioma and meningioma. It combines your own immune cells (tumor-infiltrating lymphocytes or TILs) with an immunotherapy drug (pembrolizumab) to help your body fight the tumor. It's for people who have tried other treatments without success or have no standard options left.
Beijing, Beijing MunicipalityAges 16–90 - NCT07664410Recruiting
Cancer detection with theranostic PET imaging
This trial uses a special PET scan called theranostic PET to find and track tumors in people with cancer. It may help guide treatment decisions by showing where the cancer is and how active it is.
EssenAges 18 years+ - NCT07664397RecruitingPhase 1
Imaging study of a new tracer for cancer detection
This study tests a new imaging tracer called [89Zr]DFO-YS5 that may help detect certain cancers on a PET-CT scan. The goal is to see if this tracer is safe and works well for finding tumors, which could one day help doctors plan better treatments.
San Francisco, CaliforniaAges 18 years+ - NCT07664579Recruiting
Couples coping together against cancer support program
This trial tests a supportive care program for couples facing cancer. It helps you and your partner work together to manage the challenges of a cancer diagnosis.
Duarte, CaliforniaAges 18 years+ - NCT07668453RecruitingPhase 2
Adebrelimab plus chemo for advanced bile duct cancer
This study tests adding the immunotherapy adebrelimab to standard chemotherapy (gemcitabine and nab-paclitaxel) as a first treatment for advanced biliary tract cancer that can't be removed by surgery. The goal is to see if this combination helps shrink tumors and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT05887687Recruiting
Ga-68 PET/CT scan for people with cancer
This trial looks at using a specific PET/CT scan (a whole-body imaging test) to help evaluate cancer that is confirmed or suspected. If you are eligible, you may receive this scan soon after a recent FDG PET/CT to compare or improve how cancers are identified.
Beijing, Beijing MunicipalityAges 18–75 - NCT05853783Recruiting
Testing a mouth test on biopsy samples from abnormal lesions
This trial looks at archived (saved) mouth biopsy samples to see how well the STRATICYTE™ test can identify potentially dangerous “pre-cancer-like” changes. It may help doctors screen or better understand which abnormal areas in the mouth later turn into oral cancer.
Birmingham, AlabamaAges 18 years+ - NCT07660432RecruitingPhase 1
Testing SIM0689 for advanced solid tumors
This study tests a new drug called SIM0689 for people with advanced solid tumors that have not responded to other treatments. The goal is to see if the drug is safe and effective, and researchers will look at tumor samples to understand which patients might benefit most.
Fuzhou, FujianAges 18 years+ - NCT07656116RecruitingPhase 1
Oncolytic virus therapy for advanced solid tumors
This trial tests a virus-based treatment for people with advanced solid tumors that haven't responded to standard treatments. The virus is designed to infect and kill cancer cells while leaving healthy cells alone.
Langfang, HebeiAges 18 years+ - NCT07662369RecruitingPhase 1/Phase 2
A trial of special immune cells for viral infections after transplant
This trial tests whether specially prepared donor immune cells can fight stubborn viral infections that did not get better with standard treatment. It is for people who have had a stem cell transplant and are still struggling with viruses like CMV, EBV, or others.
Shanghai, SHAges Any age - NCT07662681RecruitingPhase 1/Phase 2
Camrelizumab plus famitinib for rare head and neck cancers
This trial tests a combination of two drugs—camrelizumab (an immunotherapy) and famitinib (a targeted therapy)—for people with rare head and neck tumors that cannot be removed by surgery or have spread. It may be an option if you have not had a prior PD-1 inhibitor and have had at most one prior systemic treatment.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for malignancy?
- Yes. Clin2 currently lists 1,543 recruiting malignancy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malignancy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malignancy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.