Clinical trials
Malocclusion clinical trials
Below are recruiting malocclusion clinical trials, each written for real people, not researchers. We’re tracking 58 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06943443Enrolling by invitation
Vitamin D and expander treatment for teens
This trial looks at whether vitamin D levels affect how well a special expander (MARPE) works to fix a narrow upper jaw in teens. If you are 15–18 and have a narrow upper jaw, you may be able to join.
Konya, MeramAges 16–18 - NCT06944860Recruiting
3D-printed vs. traditional twin block braces for kids
This trial compares a new 3D-printed twin block brace to a traditional one for children with a large overbite (overjet ≥7 mm). It checks how well germs stick, how smooth the brace is, and how well it works—plus how children feel about it.
Kuala Lumpur, Kuala LumpurAges 10–14 - NCT06897787Enrolling by invitation
Jaw surgery study: how jaw position affects joint healing
This study looks at how the way the upper jaw is positioned during corrective jaw surgery affects the joint's healing over time. It may help people with a specific type of underbite who are already planning to have both upper and lower jaw surgery.
Istanbul, FatihAges 18–65 - NCT06873932Enrolling by invitation
Studying tooth movement with special aligner attachments
This trial tests whether a new type of attachment (beveled) on clear aligners works better than standard attachments for moving teeth in adults. If you are getting aligner treatment and need certain tooth movements on both sides of your mouth, this study may help improve your results.
Curitiba, ParanáAges 18 years+ - NCT06536335Recruiting
Clear aligner treatment: Comparing two timing schedules
This study compares two different schedules for clear aligner treatment (invisible braces) to see which one feels better for patients. If you have a mild misalignment (Class I) and all your permanent teeth, you may be able to join.
RomaAges 18–40 - NCT06522607Recruiting
3D Study of Palate Shape After Rapid Palatal Expansion
This trial studies how a rapid palatal expander (a device that widens the upper jaw) affects the shape of the roof of the mouth in growing children. It may help children with a posterior crossbite and a certain stage of dental development.
RomaAges 7–15 - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT06168695Recruiting
Treating front teeth crossbite to help children's speech
This study looks at how fixing a crossbite (where upper front teeth sit behind lower teeth) can improve speech in children. It may help kids who have trouble saying certain sounds because of their teeth alignment.
Tanta, Gharbia GovernorateAges 8–10 - NCT06050655Enrolling by invitation
Lingual aligners for adults: how well do they work?
This trial tests whether lingual aligners (braces placed on the inside of your teeth) are effective for straightening teeth in adults. If you are an adult planning to get orthodontic treatment, this study may be for you.
Geneva, Canton of GenevaAges 18 years+ - NCT05573308Recruiting
Clear aligner study using remote monitoring and AI checks
This trial looks at clear braces (aligner) treatment for straightening teeth, using remote monitoring and computer-guided (AI) check-ins. It may help by making treatment progress easier to track and adjust.
Antioch, IllinoisAges 12–70
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Common questions
- Are there clinical trials for malocclusion?
- Yes. Clin2 currently lists 58 recruiting malocclusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malocclusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malocclusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.