Clinical trials
Malocclusion clinical trials
Below are recruiting malocclusion clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07676695Recruiting
Jaw Device and Sound Waves for Class II Malocclusion
This trial tests a special jaw repositioning device (Twin-Block) combined with low-intensity sound waves (LIPUS) to help treat a class II malocclusion (when the lower jaw is set back) in children and teens. It aims to improve jaw alignment and joint outcomes.
CairoAges 10 months–1.2 years - NCT07645417Enrolling by invitation
Comparing Wires for Moving Upper Canine Teeth During Braces
This study tests two types of orthodontic wires to see which one more effectively moves your upper canine teeth backward when you're already wearing fixed braces. The goal is to find the best method for straightening your bite with minimal side effects.
DhakaAges 1.3 years–2.9 years - NCT07637227Recruiting
Comparing two types of clear aligners for teeth straightening
This study tests two different ways of making clear aligners (custom plastic trays that move your teeth). Researchers want to see if 3D-printed aligners work as well as traditional heat-formed ones for mild crowding or spacing.
Baghdad, Bab Al-MuadhamAges 15–30 - NCT06517927Recruiting
Long-term dental effects of childhood cancer chemo
This study looks at how chemotherapy given before age 10 affects teeth later in life. Researchers want to know if childhood cancer survivors have more dental problems than others.
BrusselsAges 12–36 - NCT05822271Recruiting
Surgery first plus aligners to improve jaw alignment
This trial studies how well a treatment plan works when you start with jaw surgery and then use clear aligners for orthodontic (teeth/jaw) finishing. It may help people whose jaw growth/position problems are mainly due to the lower jaw being too far forward or the upper jaw being too far back.
Rio de JaneiroAges 17–35 - NCT06662279Recruiting
Hyrax vs. Invisalign palatal expander study
This study compares a traditional metal palatal expander (Hyrax) to a new clear aligner-based expander (Invisalign) for widening the upper jaw in children aged 6-11. It aims to see which device works better and is more comfortable.
Laguna Hills, CaliforniaAges 6–11 - NCT07566676Recruiting
Faster Upper Front Tooth Movement With Micro-holes
This study tests a new way to move upper front teeth into better position using braces combined with tiny holes made in the bone. The goal is to correct an overbite (when upper front teeth stick out too far) more quickly and effectively.
Cairo, Nasr CityAges 15–25 - NCT07521267Recruiting
Nano-coated screws for teeth straightening in teens
This trial tests special small screws coated with nano-material to help move upper front teeth back into place during braces treatment. The screws act as anchors to make tooth movement more effective for patients with protruding upper front teeth.
Cairo, Cairo GovernorateAges 14–20 - NCT06759896Recruiting
Facemask vs braces for underbite in growing children
This trial compares a facemask device with upper braces to correct underbite in children ages 7–10. It aims to find which treatment works better to align the jaw and teeth.
Kuala Lumpur, Kuala LumpurAges 7–10 - NCT07477873Enrolling by invitation
Emotions and jaw surgery recovery study
This study looks at how patients feel emotionally and physically before and after jaw surgery. It uses special software and questionnaires to track emotions, and checks the jaw joint and muscles after surgery. The goal is to see how these relate to recovery in patients having planned jaw surgery.
Kaunas, KaunoAges 18 years+ - NCT07479290RecruitingPhase 1
Vitamin D gel to speed up tooth movement after extraction
This trial tests whether applying vitamin D near the extraction site can speed up how quickly your canine teeth move into the gap after premolars are removed. It might help shorten your orthodontic treatment.
Islamabad, FederalAges 13 years+ - NCT07455656Recruiting
Vitamin D3 or gum massage for faster canine movement with braces
This study tests whether applying vitamin D3 or a special gum massage (corticision) next to the teeth can help move your eye teeth (canines) faster after your upper first premolars are removed for braces. It is for teenagers or young adults who already need that extraction as part of their orthodontic plan.
Cairo, Cairo GovernorateAges 13–20 - NCT07399197Recruiting
Tracking tooth movement after pulling in upper canine
This trial uses 3D imaging to measure bone and root changes when pulling an upper canine that sticks out toward the cheek into its proper position. It may help doctors understand how to treat this condition better.
Sanaa, Sana'aAges 12 years+ - NCT07362160Recruiting
Comparing two types of palate expanders for kids
This trial compares a newer clear palate expander to the traditional Hyrax expander in children aged 10-14 with a crossbite. The goal is to see which device works better and is more comfortable.
Baghdad, Al-Rusafa, Bab Al-moadhamAges 10–14 - NCT07361172Recruiting
Ready-made vs custom-made braces for jaw correction
This trial compares two types of orthodontic appliances to correct a Class II bite (where the upper teeth sit too far forward). It tests whether a custom-made device works better than a ready-made one for teens.
Al Mansurah, AdakhliaAges 12–16 - NCT07350343Enrolling by invitation
Comparing 3D-printed vs thermofit clear aligners
This study compares two ways of making clear plastic aligners to straighten teeth. It looks at whether directly 3D-printed aligners work better than ones made by pressing a plastic sheet over a 3D model. This could be for people with mild to moderate teeth alignment issues.
KarbalaAges 16–40 - NCT07340242Recruiting
3D-Printed Braces vs. MARA for jaw alignment
This trial compares two types of braces (a 3D-printed removable brace and a fixed brace called MARA) to see which works better for correcting a bite problem where the lower jaw is too far back. It is designed for teenagers who are still growing and have a large overbite.
Al Mansurah, Dakahlia GovernorateAges 9–14 - NCT07307209Recruiting
Comparing two ways to move upper teeth backward with tiny screws
This trial compares two methods (sliding jigs vs retraction hooks) to move your upper teeth backward using small screws placed in your jawbone. It may help if you have a mild overbite or crowded upper teeth and want to avoid removing teeth.
SanaaAges 14 years+ - NCT07314034Recruiting
Digital full-mouth dental restoration trial
This trial tests a fully digital, face-guided approach to replace missing teeth and fix bite or cosmetic issues. It may help if you need a complete mouth rebuild and are open to a modern digital treatment process.
Shibīn al Kawm, MenoufiaAges 20–45 - NCT07290790Recruiting
Trimline Aligner Accuracy Study
This trial tests SureSmile clear aligners to see how accurately they fix common bite problems like crowding, spacing, and overbite. You may be able to join if you need mild to moderate orthodontic treatment.
Fresno, CaliforniaAges 18 years+ - NCT07115212Recruiting
Bromelain for facial swelling after jaw surgery
This trial tests whether a natural enzyme called bromelain (found in pineapple) can reduce swelling after jaw surgery. You may be eligible if you're having orthognathic surgery and don't have certain health conditions or allergies.
Lexington, KentuckyAges 18–65 - NCT07094581Recruiting
How adenoid size affects chewing muscle in children
This study uses ultrasound to see if enlarged adenoids affect the masseter muscle (a chewing muscle) in children. It may help doctors understand how breathing problems during sleep or mouth breathing impact jaw muscles.
Aydin, EfelerAges 3–8 - NCT07039071Recruiting
Laceback study for orthodontic treatment outcomes
This trial tests whether a technique called laceback improves treatment results for people getting braces. It looks at tooth movement and patient comfort.
Kuantan, PahangAges 15 years+ - NCT07040176Recruiting
Moving upper back teeth back with aligners or mini-screws
This study compares two ways to move the upper back molars backward to fix an overbite where the upper teeth stick out too far. One method uses clear aligners, the other uses tiny temporary screws in the jawbone.
ThessalonikiAges Up to 30 years
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Common questions
- Are there clinical trials for malocclusion?
- Yes. Clin2 currently lists 59 recruiting malocclusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malocclusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malocclusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.