Clinical trials
Malocclusion, Angle Class I clinical trials
Below are recruiting malocclusion, angle class i clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07773389Recruiting
Early vs late premolar removal for braces
This study compares removing two back teeth early versus later during braces treatment to see which timing leads to better tooth movement. It may help teens and young adults needing braces for crowded teeth or overbite.
IslamabadAges 13–25 - NCT05950581Recruiting
Twin-block braces with clear plates for jaw misalignment
This study tests a removable orthodontic device (twin-block with clear plates) to improve how the upper and lower jaws fit together in children. It may help if you have a specific “Class II” jaw pattern caused mainly by a lower jaw that sits back.
HamaAges 10–13 - NCT07466641Recruiting
Low-level laser or Piezocision to speed up canine tooth movement
This trial compares two treatments to see if they can safely speed up a specific tooth movement during braces. It tests a low-level laser or a minor surgical procedure called Piezocision against standard care.
Cairo, Cairo GovernorateAges 18–25 - NCT06984666Enrolling by invitation
Study of facial profiles at 45 degrees
This study looks at facial features from a 45-degree angle to see what makes a beautiful profile. It includes orthodontists, patients who have had braces for over a year, and adults without braces experience. You will have photos taken and answer some questions.
Fuzhou, FujianAges 18–50 - NCT07710391Recruiting
3D printed brace for children with underbite
This trial tests a special 3D-printed brace to fix underbite in children aged 8-13 who still have growing upper jaws. The brace encourages the upper jaw to grow forward and corrects the bite.
BaghdadAges 8–13 - NCT07703007Enrolling by invitation
Clear aligners for growing kids with mild underbite
This study tests whether clear aligners can fix a mild underbite in growing children aged 8 to 11. It compares how well the aligners move teeth and jaws compared to other treatments.
Al Mansurah, Dakahlia GovernorateAges 8–11 - NCT07752498Enrolling by invitation
Long-term results from twin block treatment
This study checks whether the results from an earlier treatment with the Twin Block appliance, which corrects bite problems, hold up over time. It looks at how stable the teeth and jaw remain years after treatment.
Jönköping, Jönköping CountyAges Any age - NCT05822271Recruiting
Surgery first plus aligners to improve jaw alignment
This trial studies how well a treatment plan works when you start with jaw surgery and then use clear aligners for orthodontic (teeth/jaw) finishing. It may help people whose jaw growth/position problems are mainly due to the lower jaw being too far forward or the upper jaw being too far back.
Rio de JaneiroAges 17–35 - NCT06050655Enrolling by invitation
Lingual aligners for adults: how well do they work?
This trial tests whether lingual aligners (braces placed on the inside of your teeth) are effective for straightening teeth in adults. If you are an adult planning to get orthodontic treatment, this study may be for you.
Geneva, Canton of GenevaAges 18 years+ - NCT06516185Recruiting
Comparing two types of clear aligners for tooth movement
This trial tests two different clear aligner designs to see which works better for straightening teeth. It is for people who need braces and have not had orthodontic treatment before.
MadridAges Any age - NCT07637227Recruiting
Comparing two types of clear aligners for teeth straightening
This study tests two different ways of making clear aligners (custom plastic trays that move your teeth). Researchers want to see if 3D-printed aligners work as well as traditional heat-formed ones for mild crowding or spacing.
Baghdad, Bab Al-MuadhamAges 15–30 - NCT07376954Enrolling by invitationPhase 1
Bite correction for children with underbite
This trial tests a special dental device that is glued to the teeth to correct an underbite in children aged 8-11. It aims to improve the way the upper and lower jaws fit together.
Al MansurahAges 8–11 - NCT07340242Recruiting
3D-Printed Braces vs. MARA for jaw alignment
This trial compares two types of braces (a 3D-printed removable brace and a fixed brace called MARA) to see which works better for correcting a bite problem where the lower jaw is too far back. It is designed for teenagers who are still growing and have a large overbite.
Al Mansurah, Dakahlia GovernorateAges 9–14 - NCT07676695Recruiting
Jaw Device and Sound Waves for Class II Malocclusion
This trial tests a special jaw repositioning device (Twin-Block) combined with low-intensity sound waves (LIPUS) to help treat a class II malocclusion (when the lower jaw is set back) in children and teens. It aims to improve jaw alignment and joint outcomes.
CairoAges 10 months–1.2 years - NCT06759896Recruiting
Facemask vs braces for underbite in growing children
This trial compares a facemask device with upper braces to correct underbite in children ages 7–10. It aims to find which treatment works better to align the jaw and teeth.
Kuala Lumpur, Kuala LumpurAges 7–10
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Common questions
- Are there clinical trials for malocclusion, angle class i?
- Yes. Clin2 currently lists 15 recruiting malocclusion, angle class i studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malocclusion, angle class i trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malocclusion, angle class i trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.