Clinical trials
Manipulation clinical trials
Below are recruiting manipulation clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06495021Recruiting
Osteopathic manipulation for newly diagnosed respiratory illness in older adults
This study tests whether osteopathic manipulation (a gentle hands-on treatment) helps older adults recover from common respiratory illnesses like bronchitis or pneumonia when added to regular care. It may be a good option for you if you're 65 or older and have just been diagnosed with a respiratory infection.
Bloomsburg, PennsylvaniaAges 65–100 - NCT06465979Recruiting
How do people with hearing loss understand speech in different settings?
This study looks at how people with healthy hearing or hearing loss understand speech in different listening environments. You might join if you have normal hearing, mild hearing loss, or use a cochlear implant, and are a competent adult English speaker.
Minneapolis, MinnesotaAges 18–65 - NCT06454344Recruiting
Sleep and childhood experiences study in young adults
This study looks at how sleep is affected by tough childhood experiences. It tests whether changing sleep patterns can help young adults who have had these experiences and currently have poor sleep.
Iowa City, IowaAges 18–29 - NCT06448351Recruiting
Changing nicotine in e-cigarettes to reduce harm
This study tests how changing the amount of nicotine in e-cigarettes affects people's behavior. It looks at two groups: young adults who already vape and older adult smokers who want to try vaping, to see if different nicotine levels can help reduce smoking or make vaping safer.
Columbus, OhioAges 21–65 - NCT06376513Recruiting
Learning to use a penile implant pump
This study checks how well patients and their partners can use the pump part of a penile prosthesis (an implant for erectile dysfunction). It may help improve training for future patients.
Pierre-BéniteAges 18 years+ - NCT06377917Recruiting
Testing timing of assisted hatching in IVF
This study compares two different timings for a lab procedure called assisted hatching (making a small opening in the embryo's outer shell) to see if one helps more embryos implant. You may be eligible if you're doing IVF with a frozen embryo transfer of a single screened embryo.
Marlton, New JerseyAges 18–42 - NCT06349590RecruitingPhase 1/Phase 2
Diet before colon cancer surgery to reduce recurrence
This trial tests whether a specific diet before colon cancer surgery can change the bacteria in your gut to help prevent the cancer from coming back or spreading. Patients who are eligible will follow the diet for a short time before their operation.
Chicago, IllinoisAges 18 years+ - NCT06312696Recruiting
Neck movement study with spinal manipulation therapy
This study tests whether a special hands-on therapy (spinal manipulation) can help people with long-term neck pain. It will measure how the neck moves and whether the treatment improves movement and reduces pain.
Minneapolis, MinnesotaAges 18–39 - NCT06275308Recruiting
Testing carbon dioxide levels on eye structure in children
This study looks at how changing the level of carbon dioxide in the blood affects a layer in the back of the eye (the choroid) in children having an eye exam under anesthesia. It may help doctors understand eye health better.
Pittsburgh, PennsylvaniaAges Up to 8 years - NCT04586959Recruiting
Uterine movement study during minimally invasive cancer surgery
This study looks at how moving the uterus during minimally invasive surgery may affect women with early-stage endometrial cancer. It may help doctors choose the safest, most effective surgical approach.
Cleveland, OhioAges 18–90 - NCT06072378Recruiting
Decision-making and memory study with brain recordings
This study looks at how the brain makes decisions and forms memories. It uses brain recordings from patients already having surgery for epilepsy to understand these processes.
New Brunswick, New JerseyAges 18–65 - NCT06041282Recruiting
Comparing treatments for early frozen shoulder
This study compares two ways to treat early frozen shoulder (also called adhesive capsulitis): manual release by a therapist versus a home exercise program. It is for people who have had symptoms for 3 months or less and have not had shoulder surgery before.
Hangzhou, ZhejiangAges 40–80 - NCT06040957Recruiting
Bone marrow vs fat cells for knee osteoarthritis treatment
This trial compares using cells from your bone marrow or belly fat to treat knee osteoarthritis, aiming to reduce pain and improve function. It's for people who haven't gotten better with standard treatments like physical therapy or medications.
BolognaAges 40–75 - NCT06015607Recruiting
Testing a new tool for colon polyp removal
This trial tests a new device to help doctors remove larger, non-cancerous polyps from the colon during a colonoscopy. It may make the procedure easier and more effective for eligible patients.
Cleveland, OhioAges 21 years+ - NCT05232032RecruitingPhase 2
Brain scan and medication study for avoiding versus approaching
This Phase 2 study looks at how a medication affects brain activity and real-life mood or anxiety behaviors. It includes people with major depression or several anxiety disorders and also healthy volunteers, using questionnaires, a smartphone, and brain imaging.
Belmont, MassachusettsAges 18–45 - NCT04788524Recruiting
Brain and stress study in depressed teens with control feelings
This study uses brain scans and short real-life mood/stress check-ins to understand how stress and perceived control work in teens with depression. It may help researchers better pinpoint brain patterns linked to depression and how teens experience control during stressful moments.
Belmont, MassachusettsAges 14–18 - NCT04369599Enrolling by invitation
Test chest vibration during ventilation for severe lung failure
This study looks at whether a special chest “vest” and related lung measurements can improve breathing in people with sudden severe lung failure who need a breathing machine. You may be eligible if you have ARDS and can safely use the vest during mechanical ventilation.
Atlanta, GeorgiaAges 18 years+ - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Phoenix, ArizonaAges 18 years+ - NCT03270631Enrolling by invitation
Exercises and soft-tissue work for chronic low back pain
This study tests whether a combination of guided movement exercises and “fascial manipulation” (hands-on work on soft tissue) can help people with long-lasting low back pain. It may be an option if your back pain has not improved with non-surgery treatments or if you have post-surgery back pain.
OuluAges Any age
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Common questions
- Are there clinical trials for manipulation?
- Yes. Clin2 currently lists 91 recruiting manipulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a manipulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a manipulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.