Clinical trials
Manipulation clinical trials
Below are recruiting manipulation clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06590116Recruiting
Spinal manipulation for chronic low back pain
This study looks at how people feel about spinal manipulation therapy for long-term low back pain. It's for adults who have had pain in their lower back for more than three months and want to share their views on this type of treatment.
Gainesville, FloridaAges 18–70 - NCT06605014Recruiting
Body alignment after stroke or mini-stroke
This study looks at how a stroke or mini-stroke affects the body's natural movement and alignment (called somatic dysfunction). Researchers want to see if there are common patterns of tightness or imbalance after a stroke, which could help guide future treatments.
Sacramento, CaliforniaAges 18 years+ - NCT06631222Recruiting
Can cognitive behavioral therapy help smartphone addiction and tension headaches?
This trial tests if cognitive behavioral therapy (a type of talk therapy that changes unhelpful thoughts and behaviors) can reduce both smartphone addiction and tension-type headaches. It is for people aged 19-34 who have frequent tension headaches and are heavy smartphone users.
Cairo, Cairo GovernorateAges 19–34 - NCT06766279Recruiting
OMT for smell loss after COVID-19
This trial tests if osteopathic manipulative treatment (OMT) can help people regain their sense of smell after COVID-19. OMT is a hands-on therapy used by osteopathic doctors to improve body function.
Las Cruces, New MexicoAges 18 years+ - NCT06816329Recruiting
Stress and depression risk study for teenage girls
This study looks at how stress affects teenage girls who may be at higher risk for depression due to a parent's history. It involves MRI scans and daily surveys on a cell phone.
Belmont, MassachusettsAges 13–15 - NCT06818175Recruiting
Study of back muscle tissue and treatment for low back pain
This study looks at the tissue in your lower back using ultrasound and physical exams. It tests a treatment to see if it helps people with new or long-term low back pain, and also compares results to people without pain.
Blacksburg, VirginiaAges 18–50 - NCT06894082Recruiting
Checking scan readings for solid cancer patients
This trial is checking how well radiologists (the doctors who read your scans) can measure tumors in patients with solid cancers. You will have your regular cancer scans, and the researchers will see if the scan-reading process runs smoothly. It's a study to improve how scan results are used in cancer care.
Marseille, Institut Paoli CalmettesAges 18 years+ - NCT06906107Recruiting
Neck pain study: testing a personalized treatment approach
This study is testing a method to see which neck pain patients benefit most from manual therapy and exercise. You may be eligible if you have neck pain (with or without arm symptoms) and have not had recent whiplash, neck surgery, or certain other conditions.
Rochester, MinnesotaAges 18–70 - NCT07080567RecruitingPhase 2
Testing maraviroc for arm recovery after stroke
This study tests whether the drug maraviroc can help people who recently had a stroke recover arm movement faster. You may be eligible if your stroke was within the last 7 days and your arm is weak but you can still wiggle your fingers.
GenevaAges 18 years+ - NCT07105943Recruiting
Exercise intensity study for heart attack recovery
This trial is testing different ways of doing exercise during cardiac rehab to see which helps people feel better and stay active. It's for people who have had a heart attack or similar event in the last year and are considered low risk.
LeiriaAges 18 years+ - NCT07137273Recruiting
Study of rewards for problem behavior
This study looks at how different rewards (reinforcements) work best for people with neurodevelopmental conditions who exhibit problem behaviors. The goal is to find ways to improve behavior support.
Auburn, AlabamaAges 6–17 - NCT07179406Recruiting
Spinal cord stimulators for restless leg syndrome
This study tests whether a spinal cord stimulator can help people with restless leg syndrome (RLS). It compares people with RLS to healthy volunteers to see if the device reduces symptoms.
Birmingham, AlabamaAges 18 years+ - NCT07216534Recruiting
Virtual reality streetscape study for psychosocial response
This study uses virtual reality to show different versions of your neighborhood to see how it affects your feelings and well-being. You will attend a two-hour visit at Ohio State University.
Columbus, OhioAges 18 years+ - NCT02257723Recruiting
Testing combined Korean herbal and therapy for hospitalized spine or joint pain
This trial studies whether a combined complementary treatment approach helps people who are hospitalized for spine or joint problems. It may help reduce the types of pain that come from those areas.
Seoul, Gangnam-GuAges Any age - NCT04369599Enrolling by invitation
Test chest vibration during ventilation for severe lung failure
This study looks at whether a special chest “vest” and related lung measurements can improve breathing in people with sudden severe lung failure who need a breathing machine. You may be eligible if you have ARDS and can safely use the vest during mechanical ventilation.
Atlanta, GeorgiaAges 18 years+ - NCT03270631Enrolling by invitation
Exercises and soft-tissue work for chronic low back pain
This study tests whether a combination of guided movement exercises and “fascial manipulation” (hands-on work on soft tissue) can help people with long-lasting low back pain. It may be an option if your back pain has not improved with non-surgery treatments or if you have post-surgery back pain.
OuluAges Any age - NCT07438912Recruiting
Mind After Midnight: A study on late-night thinking and suicide risk
This study looks at how thinking changes late at night in people who have had suicidal thoughts in the past 6 months. The goal is to understand risk and find better ways to help.
Tucson, ArizonaAges 18–55 - NCT07518732Enrolling by invitation
Thoracic Spine Treatment: Massage and Manipulation Study
This study tests whether hands-on treatments—spinal manipulation and massage—can reduce back pain, improve flexibility, and help with sleep in older adults with long-standing mid-back problems. You would receive these treatments over time and answer questions about your pain and sleep.
IstanbulAges 18–65 - NCT06965920Enrolling by invitation
Spinal pain and balance study using gentle chiropractic care
This study tests a gentle chiropractic technique called flexion distraction to see if it improves how well you move and balance while standing. It may help if you have spinal pain and can stand with mild to moderate pain.
West Palm Beach, FloridaAges 18–100 - NCT06852521Enrolling by invitation
Understanding how we see visual features
This trial tests a theory about how our brains process visual features like color and shape. You'll likely do simple tasks on a computer screen while researchers measure your responses.
Santa Barbara, CaliforniaAges 18–55 - NCT06826300Enrolling by invitation
Elbow treatment study for archers and kart drivers
This study tests a special elbow technique on healthy 18-year-old archers who also race go-karts. It looks at how the elbow treatment might affect performance.
GdanskAges 18 years+ - NCT06571877Enrolling by invitation
Bed rest study: how energy density affects eating
This study looks at how the amount of energy in food affects how much people eat when they are on bed rest. Healthy volunteers will stay in bed for a period of time, and researchers will measure their food intake to understand the relationship between energy density and appetite.
Tübingen, Baden-WurttembergAges 18–99
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Common questions
- Are there clinical trials for manipulation?
- Yes. Clin2 currently lists 94 recruiting manipulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a manipulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a manipulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.