Clinical trials
Manipulation clinical trials
Below are recruiting manipulation clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06872918Recruiting
Study of a back manipulation for lumbar disc herniation
This study tests a specific type of back manipulation (Lever Positioning Manipulation) to understand how it affects the discs in the lower spine. It may help people with a herniated disc at L4-L5 find a non-surgical treatment option.
Hangzhou, ZhejiangAges 20–60 - NCT05986370Recruiting
Study on back pain and spinal manipulation
This trial tests whether spinal manipulation therapy (a type of hands-on treatment) can help people with long-term low back pain. It also compares their results to healthy volunteers of the same age and sex.
Trois-Rivières, QuebecAges 18–60 - NCT07641621Recruiting
Chiropractic Ankle Treatment and Jump Performance Study
This study tests whether chiropractic ankle manipulation improves how high and powerfully you can jump. Researchers will work with recreationally active adults to see if this treatment affects athletic performance.
Seneca Falls, New YorkAges 18–35 - NCT06723353Recruiting
Combined therapy for belly separation in new mothers
This trial tests if a gentle hands-on treatment (visceral manipulation) plus special tape (kinesio taping) can help close the gap in your belly muscles, reduce pain, stop bladder leaks, and improve your pelvic floor strength and overall well-being after childbirth.
Karachi, SindhAges 35–45 - NCT06307886Recruiting
Uterine manipulator in endometrial cancer surgery
This trial compares survival rates for patients with early-stage endometrial cancer who have laparoscopic hysterectomy with or without a uterine manipulator (a tool used during surgery).
IstanbulAges 18–75 - NCT07498140Recruiting
Epidural steroid injection for leg and back pain
This study is testing a treatment that involves an injection to reduce nerve-related leg and back pain. It looks at how much information about the procedure affects a patient's outlook and pain relief.
Chicago, IllinoisAges Any age - NCT06883513Recruiting
Osteopathic therapy for long COVID symptoms
This trial tests if gentle hands-on treatment (osteopathic manipulative therapy) can help relieve long-lasting COVID symptoms like fatigue, brain fog, and body pain.
Louisville, KentuckyAges 18 years+ - NCT06849076Recruiting
Ankle joint motion and body awareness after stroke
This study tests if a hands-on ankle treatment can improve your sense of where your ankle is in space (proprioception) after a stroke. It looks at how well you can feel and control your ankle movement.
Bolu, MerkezAges 45–75 - NCT05687084Recruiting
Uterine manipulator vs no manipulator in endometrial cancer surgery
This trial compares using a surgical “uterine manipulator” device versus not using it during endometrial cancer surgery. It may help clarify which approach is safer and works better during planned hysterectomy.
Cuneo, ItalyAges 18–100 - NCT07786415Recruiting
Posture and physical function in college students with upper cross syndrome
This study looks at how posture affects everyday function in people with a common muscle imbalance called upper cross syndrome. It may help you understand your condition better, but you must be a college student in a specific age range and have this posture issue.
CairoAges 20–29 - NCT07876960Recruiting
Virtual reality games versus spinal adjustment for chronic back pain
This study compares two treatments for chronic low back pain: playing interactive virtual reality games and receiving spinal manipulation (a hands-on adjustment by a therapist). It aims to see which approach helps reduce pain and improve daily function.
Giza, Giza GovernorateAges 20–55 - NCT07838610Recruiting
Shoulder therapy with added back and neck moves for frozen shoulder
This study tests whether adding gentle back and neck movements to standard physical therapy helps improve shoulder pain and movement in people with frozen shoulder. The goal is to see if these extra moves make recovery faster or more complete.
Islamabad, Punjab ProvinceAges 40–60 - NCT07812285Recruiting
Osteopathic treatment for pelvic health in female runners
This study tests whether osteopathic manipulative treatment (a hands-on therapy to improve body function) can help female runners with pelvic floor issues, activity, and gait. If you're a healthy woman who runs regularly, this treatment might improve your running comfort and pelvic health.
Lexington, KentuckyAges 18–35 - NCT07786467Recruiting
Improving flu vaccine response with hands-on therapy in at-risk adults
This study tests whether a hands-on therapy called osteopathic manipulative treatment (OMT) can improve the body's response to the flu vaccine. If you are an adult who is willing to get both the flu shot and OMT, this could help make the vaccine more effective for you.
Erie, PennsylvaniaAges 18 years+ - NCT07723014Recruiting
Fascial vs muscle techniques for sacroiliac joint pain
This study compares two hands-on treatments for sacroiliac joint dysfunction, a common cause of lower back and hip pain. It aims to see which approach better reduces pain, improves movement, and helps with daily activities.
Lahore, Punjab ProvinceAges 30–45 - NCT07642713Recruiting
Manual therapy with or without spine manipulation for pelvic pain
This study tests whether manual therapy (hands-on treatment) works better alone or combined with spine manipulation for women with pain near the lower back and pelvis. If you have this type of pain, the trial may help you access treatment while researchers learn what works best.
Lahore, Punjab ProvinceAges 25–40 - NCT07633496Enrolling by invitation
Osteopathic hand therapy for healthy tears
This study tests whether gentle hands-on therapy (osteopathic manipulation) can change the makeup of your tears in a healthy way. It may help people who are interested in natural ways to support eye health.
Erie, PennsylvaniaAges 18 years+ - NCT07555873Recruiting
Osteopathic treatment versus physical therapy for neck and head dysfunction
This study compares two hands-on treatment approaches—osteopathic manipulation and physiotherapy—for chronic neck pain, headaches, and dizziness caused by cervical dysfunction. If you qualify, you'll receive one of these treatments and help researchers understand which works better.
Pristina, PejtonAges 18–65 - NCT07504640Recruiting
Spinal manipulation for heart health in children with cerebral palsy
This study tests whether a gentle spinal adjustment can improve how the heart adapts to stress in children with cerebral palsy. It may help your child's body handle daily challenges better.
LvivAges 4–18 - NCT07431788Recruiting
Uterine manipulator and sexual function after hysterectomy
This study tests whether using a uterine manipulator during abdominal hysterectomy affects sexual function after surgery. It may help women having hysterectomy for non-cancer reasons.
Istanbul, IstanbulAges 18 years+ - NCT07432750Recruiting
Osteopathic manipulation vs. wrist brace for carpal tunnel
This study tests whether osteopathic manipulation (a gentle hands-on treatment) works better than wearing a wrist brace for people with mild to moderate carpal tunnel syndrome. If you have mild or moderate carpal tunnel and haven't had surgery, this trial might help find a non-surgical option.
Old Westbury, New YorkAges 18 years+ - NCT06830148Recruiting
Tongue movement after tongue-tie release for better breastfeeding
This study tests whether gently moving the tongue after a tongue-tie release (frenotomy) helps babies breastfeed better. It's for babies under 3 months old who are having their tongue-tie cut with scissors and are breastfeeding at least some of the time.
Washington D.C., District of ColumbiaAges Up to 3 months - NCT06837025Recruiting
Fascial manipulation for kids with cerebral palsy
This trial tests a hands-on technique called fascial manipulation to see if it improves movement and walking in children with cerebral palsy. It is for families living near Helsinki.
HelsinkiAges 7–14 - NCT06851234Recruiting
Osteopathic treatment for head injuries in MMA fighters
This trial tests if osteopathic manipulative treatment (a gentle hands-on therapy) helps mixed martial artists recover from head injuries. Part 1 studies how head injuries happen during fights; Part 2 offers the treatment to fighters who get a head injury.
Greenvale, New YorkAges 18–50
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Common questions
- Are there clinical trials for manipulation?
- Yes. Clin2 currently lists 91 recruiting manipulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a manipulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a manipulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.