Clinical trials
Mastectomy clinical trials
Below are recruiting mastectomy clinical trials, each written for real people, not researchers. We’re tracking 117 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03730922Recruiting
Delayed vs immediate breast reconstruction after mastectomy and radiation
This study compares two timing options for rebuilding the breast after mastectomy followed by radiation: a reconstruction done later (delayed) versus one done sooner (delayed-immediate). The goal is to see which approach works better and is safer for recovery after treatment.
AabenraaAges 18 years+ - NCT06024187Recruiting
Cold vs. heat cutting in nipple-sparing mastectomy
This study compares two ways of cutting tissue during nipple-sparing mastectomy (breast removal with nipple preservation) followed by immediate implant reconstruction. One method uses a cold instrument, the other uses heat (electrocautery). The goal is to see which leads to better nipple survival and healing.
Guangzhou, GuangdongAges 18–75 - NCT07390448Recruiting
Comparing two pain block methods for mastectomy
This trial compares two nerve block techniques to control pain after breast cancer surgery. If you are having a mastectomy or breast-conserving surgery with lymph node removal, this study may help reduce your pain and improve recovery.
CairoAges 18–60 - NCT05899387Recruiting
Study fluid after breast surgery
This study looks at a problem called seroma, which is fluid buildup, after certain breast surgeries. It compares different situations where implants or tissue expanders are used, to better understand what to expect and how to manage it.
Augsburg, BavariaAges 18 years+ - NCT07331753Recruiting
Fat grafting with back muscle flap for breast reconstruction
This study tests if combining fat grafting with a muscle flap from the back improves breast reconstruction results after a mastectomy. It may help women who had a mastectomy and are now looking for delayed reconstruction.
Sohag, Sohag GovernorateAges 18 years+ - NCT06873893Recruiting
Nerve blocks for pain relief after mastectomy surgery
This study compares two types of ultrasound-guided nerve blocks to see which one provides better pain relief after a mastectomy. The blocks are injected near the chest wall to numb the area during and after surgery.
Cairo , AbbassyaAges 35–65 - NCT05460780Recruiting
Tissue device study for breast reconstruction after mastectomy
This first-time-in-humans study tests a tissue-engineering chamber called MATTISSE® to help the healing of breast reconstruction using specific tissue flaps after mastectomy for cancer. If you qualify, you would be assessed for safety and how well the reconstructed tissue heals.
Strasbourg, FranceAges 18 years+ - NCT06890221Recruiting
Nutrition therapy before and after breast cancer surgery
This trial tests if a special nutrition drink before and after mastectomy can help breast cancer patients recover better. It uses a body measurement called bioimpedance phase angle to see how nutrition affects your cells and healing.
Petaling Jaya, Kuala LumpurAges 18 years+ - NCT07261904Recruiting
Study of a medical tattoo for nipple reconstruction
This trial tests a medical tattoo called BIOCHROMADERM® for women or men who need a nipple-areola tattoo after breast reconstruction surgery. It checks if the tattoo is safe and works well.
LilleAges 18 years+ - NCT07257679RecruitingPhase 4
Gentle touch for arm swelling after breast cancer surgery
This study tests a gentle hand-on technique (called Gentle Touch) to see if it helps reduce arm swelling in women who developed lymphedema after breast cancer surgery. It may offer a new way to manage this side effect.
Roma, RMAges 30–75 - NCT06505577Recruiting
Comparing Tumor Size Before and After Breast Cancer Surgery
This study compares the size of a breast tumor measured before surgery (using imaging tests like mammogram or ultrasound) with the actual size found after the tumor is removed. It helps understand how accurate preoperative measurements are for patients having breast cancer surgery.
IncheonAges 19 years+ - NCT07095569Recruiting
Shoulder nerve block for pain after breast cancer radiation
This trial tests a procedure to block shoulder nerves to relieve pain caused by radiation therapy after mastectomy. It may help if you have ongoing shoulder pain after breast cancer treatment.
Cairo, Cairo GovernorateAges 18–65 - NCT07071896Recruiting
Video exercise program for breast cancer survivors
This study tests a video-based exercise program for people who recently had breast cancer surgery. It aims to help with recovery by providing guided exercises you can do at home.
San Diego, CaliforniaAges 18 years+ - NCT07059104Recruiting
Breast reconstruction after weight loss surgery study
This study looks at how breast reconstruction with implants works for women who have had major weight loss surgery. It uses national health registries to track outcomes and help doctors and patients make better choices.
GothenburgAges Any age - NCT07062458Recruiting
Comparing ways to keep nipple feeling after mastectomy
This trial compares different surgical methods to preserve nipple sensation in women having a nipple-sparing mastectomy. It aims to see which technique best helps maintain feeling in the nipple after surgery.
TorinoAges 18 years+ - NCT07053085RecruitingPhase 2
Surgery or radiation for stable HER2+ breast cancer spread
This study tests whether combining surgery or strong focused radiation with standard treatment can help people whose HER2-positive breast cancer has spread to a few spots (5 or fewer) in the body, but not the brain. It's for patients whose cancer is stable after at least 3 months of first-line therapy.
Basking Ridge, New JerseyAges 18 years+ - NCT07047872Recruiting
3D-printed breast form study for women after mastectomy
This study tests a custom 3D-printed external breast form for people who had a mastectomy without reconstruction. It aims to see if it improves comfort and satisfaction.
Rochester, MinnesotaAges 18 years+ - NCT07037537Recruiting
Nipple-sparing mastectomy with immediate reconstruction (fat and implant)
This trial tests a breast cancer surgery that removes the breast but saves the nipple, followed by immediate reconstruction with an implant and some of your own fat. It's for women with early-stage cancer that hasn't spread to lymph nodes.
Zhengzhou, HenanAges 18–70 - NCT07008339Recruiting
Nipple reconstruction using hyaluronic acid injections
This study tests if injecting a gel-like substance (hyaluronic acid) can improve nipple reconstruction in women who have had mastectomies. It aims to see if this method works better than or alongside tattoos for rebuilding the nipple-areola area.
Badalona, BarcelonaAges 18 years+ - NCT06995118Recruiting
New technique for nipple-sparing mastectomy with immediate implant reconstruction
This trial tests a special tool (HUAXI Hole 1) for a type of breast cancer surgery that removes breast tissue while saving the nipple, followed by placing an implant right away. It may be an option for women with early-stage breast cancer or those who choose preventive mastectomy.
Fuzhou, FujianAges 18–70 - NCT06982391Enrolling by invitation
Support program for breast cancer survivors
This study tests a program designed to help women who have had a mastectomy feel more supported and resilient. It may be a good fit if you are a breast cancer survivor interested in emotional and social support.
IstanbulAges 18–65 - NCT06921148Recruiting
Silk bandage for gender-affirming mastectomy recovery
This trial tests a silk protein bandage for people having double-incision mastectomy as part of female-to-male gender affirmation surgery. The goal is to see if this special bandage helps wounds heal better.
Indianapolis, IndianaAges 18 years+ - NCT06839001RecruitingPhase 3
Freezing small breast tumors instead of surgery trial
This study tests if freezing a very small early-stage breast tumor (cryoablation) can be as effective as surgery. It may be an option for people whose tumor is small enough and hasn't spread to lymph nodes or elsewhere.
São Paulo, São PauloAges 18 years+ - NCT06783179Recruiting
Recovery after mastectomy and tissue expander at Mayo Clinic Florida
This study looks at how women recover after mastectomy and tissue expander placement, comparing those who stay at the Mayo Clinic Florida Care Hotel with those who go home or stay in the hospital. It aims to see which option leads to better satisfaction and outcomes.
Jacksonville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for mastectomy?
- Yes. Clin2 currently lists 117 recruiting mastectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mastectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mastectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.